7wlp

Epstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Histone H2B type 1-O,Histone H2A type 1-D

Homo sapiens

UniProt P20671

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 4 Tegument protein BKRF4 × 3 (Q3KSS1) water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H2A1D_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 95–193; UniProt 14–112

Histone H2B type 1-O,Histone H2A type 1-D

Homo sapiens

UniProt P23527

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 4 Tegument protein BKRF4 × 3 (Q3KSS1) water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H2B1O_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 2–94; UniProt 34–126

Tegument protein BKRF4

Human gammaherpesvirus 4

UniProt Q3KSS1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 4 Histone H2B type 1-O,Histone H2A type 1-D × 1 (P20671,P23527) water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BKRF4_EBVG
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 2–88; UniProt 16–102 Author chain C; PDBConstruct 2–88; UniProt 16–102 Author chain D; PDBConstruct 2–88; UniProt 16–102

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id7wlp
Deposition date deposition_date2022-01-13
Structure title titleEpstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses
Keywords keywordsEpstein-Barr virus, BKRF4, histones, nucleosomes, DNA double-strand break repair, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7wlp__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7wlp__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7wlp__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)18.30 Å
Rg (electron density)16.99 Å
Total Rg18.05 Å
Atom count1505
Residues194
Excluded volume26895 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7wlp__assembly_1__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▶

7. Citations (1)