← Back to search
7xfg

NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1

Method: SOLUTION NMR
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Histone acetyltransferase p300

Homo sapiens

UniProt Q09472

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 NUT family member 1 × 1 （Q86Y26） ZINC ION × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3biy 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j 3i3j

69 assemblies; showing the first 12

Homodimer
4bhw 6ds6 6gyr 6gyr

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1l3e 1p4q 2k8f 2mh0 2mzd 3p57 3t92 6fgn 6fgs 6gyt 7w9v 7xez

20 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name EP300_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–94； UniProt 1723–1812

NUT family member 1

OrganismNot specified

UniProt Q86Y26

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Histone acetyltransferase p300 × 1 （Q09472） ZINC ION × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7xez 7xfg

2 assemblies

View Construct and Data Evidence
UniProt name NUTM1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–16； UniProt 403–418

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id7xfg
Deposition date deposition_date2022-04-01
Structure title titleNMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
Keywords keywordsBRD4-NUT fusion protein, CBP/p300, TAZ2 domain, F1c domain, NUT carcinoma, PEPTIDE BINDING PROTEIN, TRANSFERASE; TRANSFERASE
Experimental Method methodSOLUTION NMR
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7xfg__assembly_1__model_7

Assembly 1 · Model 7 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7xfg__assembly_1__model_7 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7xfg__assembly_1__model_7 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）16.15 Å
Rg (electron density)14.72 Å
Total Rg15.83 Å
Atom count1796
Residues118
Excluded volume15897 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7xfg__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 7xfg__assembly_1__model_2 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 7xfg__assembly_1__model_3 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 7xfg__assembly_1__model_4 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 7xfg__assembly_1__model_5 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 7xfg__assembly_1__model_6 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 7xfg__assembly_1__model_7 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 7xfg__assembly_1__model_8 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 7xfg__assembly_1__model_9 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 7xfg__assembly_1__model_10 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 7xfg__assembly_1__model_11 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 7xfg__assembly_1__model_12 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 7xfg__assembly_1__model_13 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 7xfg__assembly_1__model_14 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 7xfg__assembly_1__model_15 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 7xfg__assembly_1__model_16 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 7xfg__assembly_1__model_17 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 7xfg__assembly_1__model_18 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 7xfg__assembly_1__model_19 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 7xfg__assembly_1__model_20 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▼

6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id7xfgA01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1020 — CREB-binding Protein; Chain A
Homologous superfamily homologous superfamily10 — TAZ domain
▶

7. Citations (1)