8jrt

Cryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub.

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

26S protease regulatory subunit 7

Homo sapiens

UniProt P35998

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS7_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–433; UniProt 1–433

26S protease regulatory subunit 4

Homo sapiens

UniProt P62191

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS4_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–440; UniProt 1–440

26S protease regulatory subunit 8

Homo sapiens

UniProt P62195

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS8_HUMAN
Isoform —
PDB实体 3
链与序列区间 作者链 C; PDB构建体 1–406; UniProt 1–406

26S protease regulatory subunit 6B

Homo sapiens

UniProt P43686

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS6B_HUMAN
Isoform —
PDB实体 4
链与序列区间 作者链 D; PDB构建体 1–418; UniProt 1–418

Proteasome subunit alpha type-6

Homo sapiens

UniProt P60900

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA6_HUMAN
Isoform —
PDB实体 5
链与序列区间 作者链 G; PDB构建体 1–246; UniProt 1–246

Proteasome subunit alpha type-2

Homo sapiens

UniProt P25787

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA2_HUMAN
Isoform —
PDB实体 6
链与序列区间 作者链 H; PDB构建体 1–234; UniProt 1–234

Proteasome subunit alpha type-4

Homo sapiens

UniProt P25789

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA4_HUMAN
Isoform —
PDB实体 7
链与序列区间 作者链 I; PDB构建体 1–261; UniProt 1–261

Proteasome subunit alpha type-7

Homo sapiens

UniProt O14818

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA7_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 J; PDB构建体 1–248; UniProt 1–248

Proteasome subunit alpha type-5

Homo sapiens

UniProt P28066

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA5_HUMAN
Isoform —
PDB实体 9
链与序列区间 作者链 K; PDB构建体 1–241; UniProt 1–241

Proteasome subunit alpha type-1

Homo sapiens

UniProt P25786

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA1_HUMAN
Isoform —
PDB实体 10
链与序列区间 作者链 L; PDB构建体 1–263; UniProt 1–263

Proteasome subunit alpha type-3

Homo sapiens

UniProt P25788

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSA3_HUMAN
Isoform —
PDB实体 11
链与序列区间 作者链 M; PDB构建体 1–255; UniProt 1–255

26S proteasome non-ATPase regulatory subunit 3

Homo sapiens

UniProt O43242

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD3_HUMAN
Isoform —
PDB实体 12
链与序列区间 作者链 V; PDB构建体 1–534; UniProt 1–534

26S proteasome non-ATPase regulatory subunit 12

Homo sapiens

UniProt O00232

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSD12_HUMAN
Isoform —
PDB实体 13
链与序列区间 作者链 W; PDB构建体 1–456; UniProt 1–456

26S proteasome non-ATPase regulatory subunit 11

Homo sapiens

UniProt O00231

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSD11_HUMAN
Isoform —
PDB实体 14
链与序列区间 作者链 X; PDB构建体 1–422; UniProt 1–422

26S proteasome non-ATPase regulatory subunit 6

Homo sapiens

UniProt Q15008

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD6_HUMAN
Isoform —
PDB实体 15
链与序列区间 作者链 Y; PDB构建体 1–389; UniProt 1–389

26S proteasome non-ATPase regulatory subunit 8

Homo sapiens

UniProt P48556

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD8_HUMAN
Isoform —
PDB实体 16
链与序列区间 作者链 d; PDB构建体 1–350; UniProt 1–350

26S proteasome complex subunit DSS1

Homo sapiens

UniProt P60896

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 DSS1_HUMAN
Isoform —
PDB实体 17
链与序列区间 作者链 e; PDB构建体 1–70; UniProt 1–70

26S proteasome non-ATPase regulatory subunit 2

Homo sapiens

UniProt Q13200

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD2_HUMAN
Isoform —
PDB实体 18
链与序列区间 作者链 f; PDB构建体 1–908; UniProt 1–908

26S protease regulatory subunit 10B

Homo sapiens

UniProt P62333

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PRS10_HUMAN
Isoform —
PDB实体 19
链与序列区间 作者链 E; PDB构建体 1–389; UniProt 1–389

26S protease regulatory subunit 6A

Homo sapiens

UniProt P17980

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PRS6A_HUMAN
Isoform —
PDB实体 20
链与序列区间 作者链 F; PDB构建体 1–439; UniProt 1–439

26S proteasome non-ATPase regulatory subunit 1

Homo sapiens

UniProt Q99460

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD1_HUMAN
Isoform —
PDB实体 21
链与序列区间 作者链 U; PDB构建体 1–953; UniProt 1–953

26S proteasome non-ATPase regulatory subunit 7

Homo sapiens

UniProt P51665

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD7_HUMAN
Isoform —
PDB实体 22
链与序列区间 作者链 Z; PDB构建体 1–324; UniProt 1–324

26S proteasome non-ATPase regulatory subunit 13

Homo sapiens

UniProt Q9UNM6

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSD13_HUMAN
Isoform —
PDB实体 23
链与序列区间 作者链 a; PDB构建体 1–376; UniProt 1–376

26S proteasome non-ATPase regulatory subunit 4

Homo sapiens

UniProt P55036

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSMD4_HUMAN
Isoform —
PDB实体 24
链与序列区间 作者链 b; PDB构建体 1–377; UniProt 1–377

26S proteasome non-ATPase regulatory subunit 14

Homo sapiens

UniProt O00487

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) Polyubiquitin-B × 3 (P0CG47) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 PSDE_HUMAN
Isoform —
PDB实体 25
链与序列区间 作者链 c; PDB构建体 1–310; UniProt 1–310

Polyubiquitin-B

Homo sapiens

UniProt P0CG47

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 26S protease regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 6B × 1 (P43686) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S protease regulatory subunit 10B × 1 (P62333) 26S protease regulatory subunit 6A × 1 (P17980) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) ADENOSINE-5'-TRIPHOSPHATE × 4 MAGNESIUM ION × 5 ADENOSINE-5'-DIPHOSPHATE × 2 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 UBB_HUMAN
Isoform —
PDB实体 26
链与序列区间 作者链 u; PDB构建体 6–81; UniProt 77–152 作者链 v; PDB构建体 6–81; UniProt 77–152 作者链 w; PDB构建体 6–81; UniProt 77–152

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id8jrt
沉积日期 deposition_date2023-06-17
结构标题 titleCryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub.
关键词 keywordsprotein degradation, macromolecular complex, ubiquitin-proteasome system, CYTOSOLIC PROTEIN; CYTOSOLIC PROTEIN
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

8jrt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

8jrt__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

8jrt__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)75.20 Å
Rg(电子密度)74.59 Å
总 Rg74.38 Å
原子数66765
残基数9029
排除体积1179700 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 8jrt__assembly_1__model_1 28-meric (28) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (29)

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7. 引用文献 (1)