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8pje

Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

HLA class II histocompatibility antigen, DR alpha chain

Homo sapiens

UniProt P01903

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DRB1 beta chain × 1 （P01911） Hemagglutinin × 1 （P03435） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 13 GLYCEROL × 8 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DRB1 beta chain × 1 （P01911） Hemagglutinin × 1 （P03435） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 14 GLYCEROL × 3 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1a6a 1a6a 1aqd 1aqd 1aqd 1aqd 1bx2 1bx2 1bx2 1d5m 1d5x 1d5z

220 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name DRA_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–186； UniProt 26–207 Author chain D； PDBConstruct 5–186； UniProt 26–207

HLA class II histocompatibility antigen, DRB1 beta chain

Homo sapiens

UniProt P01911

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DR alpha chain × 1 （P01903） Hemagglutinin × 1 （P03435） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 13 GLYCEROL × 8 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DR alpha chain × 1 （P01903） Hemagglutinin × 1 （P03435） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 14 GLYCEROL × 3 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2wbj 2wbj 5v4m 5v4m 5v4m 5v4m 8pje 8pje 8pjf 8pjg 8tbp 8tbp

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name DRB1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 5–194； UniProt 30–219 Author chain E； PDBConstruct 5–194； UniProt 30–219

Hemagglutinin

OrganismNot specified

UniProt P03435

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DR alpha chain × 1 （P01903） HLA class II histocompatibility antigen, DRB1 beta chain × 1 （P01911） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 13 GLYCEROL × 8 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 HLA class II histocompatibility antigen, DR alpha chain × 1 （P01903） HLA class II histocompatibility antigen, DRB1 beta chain × 1 （P01911） 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 1,2-ETHANEDIOL × 14 GLYCEROL × 3 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4gms 4o58 6r0e 8inr 8ioc 8iod 8jru 8jrv 8pje 8pje 8pjf 8pjg

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HEMA_I75A3
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–13； UniProt 323–335 Author chain F； PDBConstruct 1–13； UniProt 323–335

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8pje
Deposition date deposition_date2023-06-23
Structure title titleHuman Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT
Keywords keywords;HLA-II, HLA-DR, HLA-DR1, human leukocyte antigen, major histocompatibility complex, major histocompatibility complex class 2, influenza A virus, flu, haemagglutinin, HA, infection, vaccine, IMMUNE SYSTEM ;; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8pje__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8pje__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8pje__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）25.01 Å
Rg (electron density)24.06 Å
Total Rg24.95 Å
Atom count3269
Residues385
Excluded volume58040 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8pje__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8pje__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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7. Citations (1)