← Back to search
8r3x

Crystal structure of aPKC Iota kinase domain with LLGL2 peptide

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein kinase C iota type

Homo sapiens

UniProt P41743

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 LLGL scribble cell polarity complex component 2 × 1 （Q6P1M3） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 LLGL scribble cell polarity complex component 2 × 1 （Q6P1M3） water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1vd2 1zrz 3a8w 3a8w 3a8x 3a8x 3zh8 3zh8 3zh8 5li9 6ilz 6ilz

14 assemblies; showing the first 12

Homodimer
3a8w 3a8x

2 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1wmh 5li1 5lih 5lih 8r3x 8r3x 8r3y 9ejk 9ejl 9ejm

10 assemblies

View Construct and Data Evidence
UniProt name KPCI_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–356； UniProt 241–596 Author chain B； PDBConstruct 1–356； UniProt 241–596

LLGL scribble cell polarity complex component 2

OrganismNot specified

UniProt Q6P1M3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Protein kinase C iota type × 1 （P41743） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Protein kinase C iota type × 1 （P41743） water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
6n8p 6n8q 6n8r 6n8s 6n8s

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3wp0 3wp1 8r3x 8r3x 9ejk 9ejl 9ejm

7 assemblies

View Construct and Data Evidence
UniProt name L2GL2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–20； UniProt 641–660 Author chain D； PDBConstruct 1–20； UniProt 641–660

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8r3x
Deposition date deposition_date2023-11-10
Structure title titleCrystal structure of aPKC Iota kinase domain with LLGL2 peptide
Keywords keywordsKinase, Polarity, Kinase substrate complex., CYTOSOLIC PROTEIN; CYTOSOLIC PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8r3x__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8r3x__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8r3x__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）21.88 Å
Rg (electron density)20.57 Å
Total Rg21.53 Å
Atom count2861
Residues348
Excluded volume50741 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8r3x__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8r3x__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▶

7. Citations (1)