8y37

Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Large ribosomal subunit protein bL33B

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL332_STAAW
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 1； PDBConstruct 1–47； UniProt 2–48

Large ribosomal subunit protein bL34

OrganismNot specified

UniProt P66254

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL34_STAAW
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 2； PDBConstruct 1–43； UniProt 2–44

Large ribosomal subunit protein bL35

OrganismNot specified

UniProt P66277

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL35_STAAW
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain 3； PDBConstruct 1–64； UniProt 2–65

Large ribosomal subunit protein bL36

OrganismNot specified

UniProt P66300

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL36_STAAW
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 4； PDBConstruct 1–37； UniProt 1–37

Large ribosomal subunit protein uL2

OrganismNot specified

UniProt P60433

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL2_STAAW
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain C； PDBConstruct 1–274； UniProt 2–275

Large ribosomal subunit protein uL3

OrganismNot specified

UniProt P60450

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL3_STAAW
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain D； PDBConstruct 1–215； UniProt 2–216

Large ribosomal subunit protein uL4

OrganismNot specified

UniProt P61060

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL4_STAAW
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain E； PDBConstruct 1–206； UniProt 2–207

Large ribosomal subunit protein uL5

OrganismNot specified

UniProt Q7A083

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL5_STAAW
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain F； PDBConstruct 1–175； UniProt 2–176

Large ribosomal subunit protein uL6

OrganismNot specified

UniProt Q7A084

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL6_STAAW
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain G； PDBConstruct 1–175； UniProt 2–176

Large ribosomal subunit protein uL13

OrganismNot specified

UniProt Q7A089

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL13_STAAW
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain H； PDBConstruct 1–145； UniProt 1–145

Large ribosomal subunit protein uL14

OrganismNot specified

UniProt Q7A081

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL14_STAAW
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain I； PDBConstruct 1–122； UniProt 1–122

Large ribosomal subunit protein uL15

OrganismNot specified

UniProt P0A0F7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL15_STAAW
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain J； PDBConstruct 1–146； UniProt 1–146

Large ribosomal subunit protein uL16

OrganismNot specified

UniProt Q7A080

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL16_STAAW
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain K； PDBConstruct 1–137； UniProt 1–137

Large ribosomal subunit protein bL17

OrganismNot specified

UniProt Q7A087

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL17_STAAW
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain L； PDBConstruct 1–120； UniProt 3–122

Large ribosomal subunit protein uL18

OrganismNot specified

UniProt Q7A085

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL18_STAAW
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain M； PDBConstruct 1–119； UniProt 1–119

Large ribosomal subunit protein bL19

OrganismNot specified

UniProt Q8NX05

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL19_STAAW
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain N； PDBConstruct 1–114； UniProt 2–115

Large ribosomal subunit protein bL20

OrganismNot specified

UniProt P66109

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL20_STAAW
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain O； PDBConstruct 1–116； UniProt 2–117

Large ribosomal subunit protein bL21

OrganismNot specified

UniProt Q7A0Q2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL21_STAAW
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain P； PDBConstruct 1–102； UniProt 1–102

Large ribosomal subunit protein uL22

OrganismNot specified

UniProt Q7A079

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL22_STAAW
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain Q； PDBConstruct 1–117； UniProt 1–117

Large ribosomal subunit protein uL23

OrganismNot specified

UniProt Q7A078

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL23_STAAW
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain R； PDBConstruct 1–89； UniProt 2–90

Large ribosomal subunit protein uL24

OrganismNot specified

UniProt P60736

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL24_STAAW
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain S； PDBConstruct 1–103； UniProt 2–104

Large ribosomal subunit protein bL25

OrganismNot specified

UniProt Q7A1S4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL25_STAAW
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain T； PDBConstruct 1–94； UniProt 2–95

Large ribosomal subunit protein bL27

OrganismNot specified

UniProt P66134

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL27_STAAW
Isoform	—
PDB entities	25
Chains and sequence ranges	Author chain U； PDBConstruct 1–82； UniProt 12–93

Large ribosomal subunit protein bL28

OrganismNot specified

UniProt P66154

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL28_STAAW
Isoform	—
PDB entities	26
Chains and sequence ranges	Author chain V； PDBConstruct 1–58； UniProt 3–60

Large ribosomal subunit protein uL29

OrganismNot specified

UniProt P66174

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL29_STAAW
Isoform	—
PDB entities	27
Chains and sequence ranges	Author chain W； PDBConstruct 1–67； UniProt 2–68

Large ribosomal subunit protein uL30

OrganismNot specified

UniProt P0A0G1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein bL31B × 1 （P66197） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL30_STAAW
Isoform	—
PDB entities	28
Chains and sequence ranges	Author chain X； PDBConstruct 1–58； UniProt 2–59

Large ribosomal subunit protein bL31B

OrganismNot specified

UniProt P66197

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL32 × 1 （P66211） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL31B_STAAW
Isoform	—
PDB entities	29
Chains and sequence ranges	Author chain Y； PDBConstruct 1–59； UniProt 1–59

Large ribosomal subunit protein bL32

OrganismNot specified

UniProt P66211

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 28 RNA 2	Large ribosomal subunit protein bL33B × 1 （P66232） Large ribosomal subunit protein bL34 × 1 （P66254） Large ribosomal subunit protein bL35 × 1 （P66277） Large ribosomal subunit protein bL36 × 1 （P66300） 23S ribosomal RNA × 1 5S ribosomal RNA × 1 Large ribosomal subunit protein uL2 × 1 （P60433） Large ribosomal subunit protein uL3 × 1 （P60450） Large ribosomal subunit protein uL4 × 1 （P61060） Large ribosomal subunit protein uL5 × 1 （Q7A083） Large ribosomal subunit protein uL6 × 1 （Q7A084） Large ribosomal subunit protein uL13 × 1 （Q7A089） Large ribosomal subunit protein uL14 × 1 （Q7A081） Large ribosomal subunit protein uL15 × 1 （P0A0F7） Large ribosomal subunit protein uL16 × 1 （Q7A080） Large ribosomal subunit protein bL17 × 1 （Q7A087） Large ribosomal subunit protein uL18 × 1 （Q7A085） Large ribosomal subunit protein bL19 × 1 （Q8NX05） Large ribosomal subunit protein bL20 × 1 （P66109） Large ribosomal subunit protein bL21 × 1 （Q7A0Q2） Large ribosomal subunit protein uL22 × 1 （Q7A079） Large ribosomal subunit protein uL23 × 1 （Q7A078） Large ribosomal subunit protein uL24 × 1 （P60736） Large ribosomal subunit protein bL25 × 1 （Q7A1S4） Large ribosomal subunit protein bL27 × 1 （P66134） Large ribosomal subunit protein bL28 × 1 （P66154） Large ribosomal subunit protein uL29 × 1 （P66174） Large ribosomal subunit protein uL30 × 1 （P0A0G1） Large ribosomal subunit protein bL31B × 1 （P66197） ;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ; × 1 MAGNESIUM ION × 12 water × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL32_STAAW
Isoform	—
PDB entities	30
Chains and sequence ranges	Author chain Z； PDBConstruct 1–48； UniProt 2–49

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8y37
Deposition date deposition_date	2024-01-28
Structure title title	Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.
Keywords keywords	antibiotic, ribosome; RIBOSOME
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8y37__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8y37__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8y37__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	69.84 Å
Rg (electron density)	70.42 Å
Total Rg	70.43 Å
Atom count	88295
Residues	6120
Excluded volume	1336300 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8y37__assembly_1__model_1`	30-meric （30）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (33)

Entity 1 Entity 1 polymer

Description description	Large ribosomal subunit protein bL33B
Molecular weight formula_weight	5684.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	1
Atom count atom_count	88301

RVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRET

Entity 2 Entity 2 polymer

Description description	Large ribosomal subunit protein bL34
Molecular weight formula_weight	5252.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2

VKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLS

Entity 3 Entity 3 polymer

Description description	Large ribosomal subunit protein bL35
Molecular weight formula_weight	7462.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3

PKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYK

Entity 4 Entity 4 polymer

Description description	Large ribosomal subunit protein bL36
Molecular weight formula_weight	4318.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4

MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG

Entity 5 Entity 5 polymer

Description description	23S ribosomal RNA
Molecular weight formula_weight	946121.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	A

UUAAGUUAUUAAGGGCGCACGGUGGAUGCCUUGGCACUAGAAGCCGAUGAAGGACGUUACUAACGACGAUAUGCUUUGGGGAGCUGUAAGUAAGCUUUGAUCCAGAGAUUUCCGAAUGGGGAAACCCAGCAUGAGUUAUGUCAUGUUAUCGAUAUGUGAAUACAUAGCAUAUCAGAAGGCACACCCGGAGAACUGAAACAUCUUAGUACCCGGAGGAAGAGAAAGAAAAUUCGAUUCCCUUAGUAGCGGCGAGCGAAAUGGGAAGAGCCCAAACCAACAAGCUUGCUUGUUGGGGUUGUAGGACACUCUAUACGGAGUUACAAAGGACGACAUUAGACGAAUCAUCUGGAAAGAUGAAUCAAAGAAGGUAAUAAUCCUGUAGUCGAAAAUGUUGUCUCUCUUGAGUGGAUCCUGAGUACGACGGAGCACGUGAAAUUCCGUCGGAAUCUGGGAGGACCAUCUCCUAAGGCUAAAUACUCUCUAGUGACCGAUAGUGAACCAGUACCGUGAGGGAAAGGUGAAAAGCACCCCGGAAGGGGAGUGAAAUAGAACCUGAAACCGUGUGCUUACAAGUAGUCAGAGCCCGUUAAUGGGUGAUGGCGUGCCUUUUGUAGAAUGAACCGGCGAGUUACGAUUUGAUGCAAGGUUAAGCAGUAAAUGUGGAGCCGUAGCGAAAGCGAGUCUGAAUAGGGCGUUUAGUAUUUGGUCGUAGACCCGAAACCAGGUGAUCUACCCUUGGUCAGGUUGAAGUUCAGGUAACACUGAAUGGAGGACCGAACCGACUUACGUUGAAAAGUGAGCGGAUGAACUGAGGGUAGCGGAGAAAUUCCAAUCGAACCUGGAGAUAGCUGGUUCUCUCCGAAAUAGCUUUAGGGCUAGCCUCAAGUGAUGAUUAUUGGAGGUAGAGCACUGUUUGGACGAGGGGCCCCUCUCGGGUUACCGAAUUCAGACAAACUCCGAAUGCCAAUUAAUUUAACUUGGGAGUCAGAACAUGGGUGAUAAGGUCCGUGUUCGAAAGGGAAACAGCCCAGACCACCAGCUAAGGUCCCAAAAUAUAUGUUAAGUGGAAAAGGAUGUGGCGUUGCCCAGACAACUAGGAUGUUGGCUUAGAAGCAGCCAUCAUUUAAAGAGUGCGUAAUAGCUCACUAGUCGAGUGACACUGCGCCGAAAAUGUACCGGGGCUAAACAUAUUACCGAAGCUGUGGAUUGUCCUUUGGACAAUGGUAGGAGAGCGUUCUAAGGGCGUUGAAGCAUGAUCGUAAGGACAUGUGGAGCGCUUAGAAGUGAGAAUGCCGGUGUGAGUAGCGAAAGACGGGUGAGAAUCCCGUCCACCGAUUGACUAAGGUUUCCAGAGGAAGGCUCGUCCGCUCUGGGUUAGUCGGGUCCUAAGCUGAGGCCGACAGGCGUAGGCGAUGGAUAACAGGUUGAUAUUCCUGUACCACCUAUAAUCGUUUUAAUCGAUGGGGGGACGCAGUAGGAUAGGCGAAGCGUGCGAUUGGAUUGCACGUCUAAGCAGUAAGGCUGAGUAUUAGGCAAAUCCGGUACUCGUUAAGGCUGAGCUGUGAUGGGGAGAAGACAUUGUGUCUUCGAGUCGUUGAUUUCACACUGCCGAGAAAAGCCUCUAGAUAGAAAAUAGGUGCCCGUACCGCAAACCGACACAGGUAGUCAAGAUGAGAAUUCUAAGGUGAGCGAGCGAACUCUCGUUAAGGAACUCGGCAAAAUGACCCCGUAACUUCGGGAGAAGGGGUGCUCUUUAGGGUUAACGCCCAGAAGAGCCGCAGUGAAUAGGCCCAAGCGACUGUUUAUCAAAAACACAGGUCUCUGCUAAACCGUAAGGUGAUGUAUAGGGGCUGACGCCUGCCCGGUGCUGGAAGGUUAAGAGGAGUGGUUAGCUUCUGCGAAGCUACGAAUCGAAGCCCCAGUAAACGGCGGCCGUAACUAUAACGGUCCUAAGGUAGCGAAAUUCCUUGUCGGGUAAGUUCCGACCCGCACGAAAGGCGUAACGAUUUGGGCACUGUCUCAACGAGAGACUCGGUGAAAUCAUAGUACCUGUGAAGAUGCAGGUUACCCGCGACAGGACGGAAAGACCCCGUGGAGCUUUACUGUAGCCUGAUAUUGAAAUUCGGCACAGCUUGUACAGGAUAGGUAGGAGCCUUUGAAACGUGAGCGCUAGCUUACGUGGAGGCGCUGGUGGGAUACUACCCUAGCUGUGUUGGCUUUCUAACCCGCACCACUUAUCGUGGUGGGAGACAGUGUCAGGCGGGCAGUUUGACUGGGGCGGUCGCCUCCUAAAAGGUAACGGAGGCGCUCAAAGGUUCCCUCAGAAUGGUUGGAAAUCAUUCAUAGAGUGUAAAGGCAUAAGGGAGCUUGACUGCGAGACCUACAAGUCGAGCAGGGUCGAAAGACGGACUUAGUGAUCCGGUGGUUCCGCAUGGAAGGGCCAUCGCUCAACGGAUAAAAGCUACCCCGGGGAUAACAGGCUUAUCUCCCCCAAGAGUUCACAUCGACGGGGAGGUUUGGCACCUCGAUGUCGGCUCAUCGCAUCCUGGGGCUGUAGUCGGUCCCAAGGGUUGGGCUGUUCGCCCAUUAAAGCGGUACGCGAGCUGGGUUCAGAACGUCGUGAGACAGUUCGGUCCCUAUCCGUCGUGGGCGUAGGAAAUUUGAGAGGAGCUGUCCUUAGUACGAGAGGACCGGGAUGGACAUACCUCUGGUGUACCAGUUGUCGUGCCAACGGCAUAGCUGGGUAGCUAUGUGUGGACGGGAUAAGUGCUGAAAGCAUCUAAGCAUGAAGCCCCCCUCAAGAUGAGAUUUCCCAACUUCGGUUAUAAGAUCCCUCAAAGAUGAUGAGGUUAAUAGGUUCGAGGUGGAAGCAUGGUGACAUGUGGAGCUGACGAAUACUAAUCGAUCGAAGACUUAAUCAA

Entity 6 Entity 6 polymer

Description description	5S ribosomal RNA
Molecular weight formula_weight	36974.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	B

UCUGGUGACUAUAGCAAGGAGGUCACACCUGUUCCCAUGCCGAACACAGAAGUUAAGCUCCUUAGCGUCGAUGGUAGUCGAACUUACGUUCCGCUAGAGUAGAACGUUGCCAGGC

Entity 7 Entity 7 polymer

Description description	Large ribosomal subunit protein uL2
Molecular weight formula_weight	29827.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

AIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRK

Entity 8 Entity 8 polymer

Description description	Large ribosomal subunit protein uL3
Molecular weight formula_weight	23199.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

TKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIK

Entity 9 Entity 9 polymer

Description description	Large ribosomal subunit protein uL4
Molecular weight formula_weight	22364.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

ANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG

Entity 10 Entity 10 polymer

Description description	Large ribosomal subunit protein uL5
Molecular weight formula_weight	19731.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

NRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMP

Entity 11 Entity 11 polymer

Description description	Large ribosomal subunit protein uL6
Molecular weight formula_weight	19501.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

SRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKT

Entity 12 Entity 12 polymer

Description description	Large ribosomal subunit protein uL13
Molecular weight formula_weight	16359.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG

Entity 13 Entity 13 polymer

Description description	Large ribosomal subunit protein uL14
Molecular weight formula_weight	13157.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL

Entity 14 Entity 14 polymer

Description description	Large ribosomal subunit protein uL15
Molecular weight formula_weight	15628.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI

Entity 15 Entity 15 polymer

Description description	Large ribosomal subunit protein uL16
Molecular weight formula_weight	15599.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREEL

Entity 16 Entity 16 polymer

Description description	Large ribosomal subunit protein bL17
Molecular weight formula_weight	13583.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

YRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

Entity 17 Entity 17 polymer

Description description	Large ribosomal subunit protein uL18
Molecular weight formula_weight	13124.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF

Entity 18 Entity 18 polymer

Description description	Large ribosomal subunit protein bL19
Molecular weight formula_weight	13104.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

TNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEI

Entity 19 Entity 19 polymer

Description description	Large ribosomal subunit protein bL20
Molecular weight formula_weight	13459.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

PRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDAL

Entity 20 Entity 20 polymer

Description description	Large ribosomal subunit protein bL21
Molecular weight formula_weight	11354.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA

Entity 21 Entity 21 polymer

Description description	Large ribosomal subunit protein uL22
Molecular weight formula_weight	12857.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA

Entity 22 Entity 22 polymer

Description description	Large ribosomal subunit protein uL23
Molecular weight formula_weight	10380.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

EARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLF

Entity 23 Entity 23 polymer

Description description	Large ribosomal subunit protein uL24
Molecular weight formula_weight	11316.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

HIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSN

Entity 24 Entity 24 polymer

Description description	Large ribosomal subunit protein bL25
Molecular weight formula_weight	10462.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

ASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAIN

Entity 25 Entity 25 polymer

Description description	Large ribosomal subunit protein bL27
Molecular weight formula_weight	8911.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	U

KKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVA

Entity 26 Entity 26 polymer

Description description	Large ribosomal subunit protein bL28
Molecular weight formula_weight	6550.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	V

KQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVT

Entity 27 Entity 27 polymer

Description description	Large ribosomal subunit protein uL29
Molecular weight formula_weight	7845.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

KAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKAN

Entity 28 Entity 28 polymer

Description description	Large ribosomal subunit protein uL30
Molecular weight formula_weight	6434.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	X

AKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLVTVEEK

Entity 29 Entity 29 polymer

Description description	Large ribosomal subunit protein bL31B
Molecular weight formula_weight	6909.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Y

MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDGKEYPVIRLDISSDSHPFYT

Entity 30 Entity 30 polymer

Description description	Large ribosomal subunit protein bL32
Molecular weight formula_weight	5569.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

AVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSY

Entity 31 Entity 31 non-polymer

Description description	;7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid ;
Molecular weight formula_weight	969.1 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 32 Entity 32 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	12

Entity 33 Entity 33 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	6

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	2.53 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	68392

Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.

1. Protein Identity and Related Structures Protein Identity & Related Structures

Large ribosomal subunit protein bL33B

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL34

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL35

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL36

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL13

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer