9bp7

Cryo-EM structure of human heteromeric Glycine Receptor alpha3S346E-beta in presence of glycine and 2,6-DTBP

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Glycine receptor subunit alpha-3

Homo sapiens

UniProt O75311

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Glycine receptor subunit beta,Green fluorescent protein × 1 (A0A9X4KGN5,P48167) 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 GLYCINE × 3 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name GLRA3_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–422; UniProt 34–464 Author chain B; PDBConstruct 1–422; UniProt 34–464 Author chain C; PDBConstruct 1–422; UniProt 34–464 Author chain D; PDBConstruct 1–422; UniProt 34–464

Glycine receptor subunit beta,Green fluorescent protein

Homo sapiens

UniProt A0A9X4KGN5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Glycine receptor subunit alpha-3 × 4 (O75311) 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 GLYCINE × 3 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A9X4KGN5_9BACI
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E; PDBConstruct 339–578; UniProt 9–248

Glycine receptor subunit beta,Green fluorescent protein

Homo sapiens

UniProt P48167

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Glycine receptor subunit alpha-3 × 4 (O75311) 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 GLYCINE × 3 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name GLRB_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E; PDBConstruct 1–331; UniProt 25–355 Author chain E; PDBConstruct 583–680; UniProt 400–497

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9bp7
Deposition date deposition_date2024-05-07
Structure title titleCryo-EM structure of human heteromeric Glycine Receptor alpha3S346E-beta in presence of glycine and 2,6-DTBP
Keywords keywordsglycine receptor subunit alpha-3, glycine receptor subunit beta, Green fluorescent protein, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9bp7__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9bp7__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9bp7__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)39.44 Å
Rg (electron density)39.01 Å
Total Rg39.31 Å
Atom count13722
Residues1703
Excluded volume247780 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9bp7__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)