9e8l

Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase

Method: ELECTRON MICROSCOPY Dmax: 258.8 Å Quality: EXCELLENT

1. 蛋白身份与相关结构 Protein Identity & Related Structures

26S proteasome regulatory subunit 7

物种未注明

UniProt P35998

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 A; UniProt 1–433 未记录 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 130 个其他 PDB 条目、130 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS7_HUMAN
Isoform
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–433; UniProt 1–433

26S proteasome regulatory subunit 4

物种未注明

UniProt P62191

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 B; UniProt 1–440 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 130 个其他 PDB 条目、130 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS4_HUMAN
Isoform
PDB实体 2
链与序列区间 作者链 B; PDB构建体 1–440; UniProt 1–440

26S protease regulatory subunit 8

物种未注明

UniProt P62195

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 C; UniProt 1–406 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 127 个其他 PDB 条目、127 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS8_HUMAN
Isoform
PDB实体 3
链与序列区间 作者链 C; PDB构建体 1–406; UniProt 1–406

26S proteasome regulatory subunit 6B

物种未注明

UniProt P43686

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 D; UniProt 1–418 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 130 个其他 PDB 条目、130 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS6B_HUMAN
Isoform
PDB实体 4
链与序列区间 作者链 D; PDB构建体 1–418; UniProt 1–418

26S protease regulatory subunit 10B

物种未注明

UniProt P62333

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 E; UniProt 1–389 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 54 个其他 PDB 条目、54 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS10_HUMAN
Isoform
PDB实体 5
链与序列区间 作者链 E; PDB构建体 1–389; UniProt 1–389

26S proteasome regulatory subunit 6A

物种未注明

UniProt P17980

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 F; UniProt 1–439 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 129 个其他 PDB 条目、129 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PRS6A_HUMAN
Isoform
PDB实体 6
链与序列区间 作者链 F; PDB构建体 1–439; UniProt 1–439

Proteasome subunit alpha type-6

物种未注明

UniProt P60900

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 G; UniProt 1–246 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA6_HUMAN
Isoform
PDB实体 7
链与序列区间 作者链 G; PDB构建体 1–246; UniProt 1–246

Proteasome subunit alpha type-2

物种未注明

UniProt P25787

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 H; UniProt 1–234 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA2_HUMAN
Isoform
PDB实体 8
链与序列区间 作者链 H; PDB构建体 1–234; UniProt 1–234

Proteasome subunit alpha type-4

物种未注明

UniProt P25789

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 I; UniProt 1–261 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA4_HUMAN
Isoform
PDB实体 9
链与序列区间 作者链 I; PDB构建体 1–261; UniProt 1–261

Proteasome subunit alpha type-7

物种未注明

UniProt O14818

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 J; UniProt 1–248 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA7_HUMAN
Isoform
PDB实体 10
链与序列区间 作者链 J; PDB构建体 1–248; UniProt 1–248

Proteasome subunit alpha type-5

物种未注明

UniProt P28066

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 K; UniProt 1–241 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA5_HUMAN
Isoform
PDB实体 11
链与序列区间 作者链 K; PDB构建体 1–241; UniProt 1–241

Proteasome subunit alpha type-1

物种未注明

UniProt P25786

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 L; UniProt 1–263 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 170 个其他 PDB 条目、171 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA1_HUMAN
Isoform
PDB实体 12
链与序列区间 作者链 L; PDB构建体 1–263; UniProt 1–263

Proteasome subunit alpha type-3

物种未注明

UniProt P25788

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 M; UniProt 1–255 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 172 个其他 PDB 条目、175 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSA3_HUMAN
Isoform
PDB实体 13
链与序列区间 作者链 M; PDB构建体 1–255; UniProt 1–255

26S proteasome non-ATPase regulatory subunit 1

物种未注明

UniProt Q99460

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 U; UniProt 1–953 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 122 个其他 PDB 条目、125 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD1_HUMAN
Isoform
PDB实体 14
链与序列区间 作者链 U; PDB构建体 1–953; UniProt 1–953

26S proteasome non-ATPase regulatory subunit 3

物种未注明

UniProt O43242

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 V; UniProt 1–534 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 115 个其他 PDB 条目、115 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD3_HUMAN
Isoform
PDB实体 15
链与序列区间 作者链 V; PDB构建体 1–534; UniProt 1–534

26S proteasome non-ATPase regulatory subunit 12

物种未注明

UniProt O00232

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 W; UniProt 1–456 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 115 个其他 PDB 条目、115 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSD12_HUMAN
Isoform
PDB实体 16
链与序列区间 作者链 W; PDB构建体 1–456; UniProt 1–456

26S proteasome non-ATPase regulatory subunit 11

物种未注明

UniProt O00231

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 X; UniProt 1–422 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 115 个其他 PDB 条目、115 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSD11_HUMAN
Isoform
PDB实体 17
链与序列区间 作者链 X; PDB构建体 1–422; UniProt 1–422

26S proteasome non-ATPase regulatory subunit 6

物种未注明

UniProt Q15008

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 Y; UniProt 1–389 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 115 个其他 PDB 条目、115 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD6_HUMAN
Isoform
PDB实体 18
链与序列区间 作者链 Y; PDB构建体 1–389; UniProt 1–389

26S proteasome non-ATPase regulatory subunit 7

物种未注明

UniProt P51665

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 Z; UniProt 1–324 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 117 个其他 PDB 条目、120 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD7_HUMAN
Isoform
PDB实体 19
链与序列区间 作者链 Z; PDB构建体 1–324; UniProt 1–324

26S proteasome non-ATPase regulatory subunit 13

物种未注明

UniProt Q9UNM6

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 a; UniProt 1–376 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 114 个其他 PDB 条目、114 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSD13_HUMAN
Isoform
PDB实体 20
链与序列区间 作者链 a; PDB构建体 1–376; UniProt 1–376

26S proteasome non-ATPase regulatory subunit 4

物种未注明

UniProt P55036

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 b; UniProt 1–377 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 124 个其他 PDB 条目、124 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD4_HUMAN
Isoform
PDB实体 21
链与序列区间 作者链 b; PDB构建体 1–377; UniProt 1–377

26S proteasome non-ATPase regulatory subunit 14

Homo sapiens

UniProt O00487

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 c; UniProt 1–310 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 121 个其他 PDB 条目、121 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSDE_HUMAN
Isoform
PDB实体 22
链与序列区间 作者链 c; PDB构建体 1–310; UniProt 1–310

26S proteasome non-ATPase regulatory subunit 8

物种未注明

UniProt P48556

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 d; UniProt 1–350 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 115 个其他 PDB 条目、115 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD8_HUMAN
Isoform
PDB实体 23
链与序列区间 作者链 d; PDB构建体 1–350; UniProt 1–350

26S proteasome complex subunit SEM1

物种未注明

UniProt P60896

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 e; UniProt 1–70 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 124 个其他 PDB 条目、126 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 SEM1_HUMAN
Isoform
PDB实体 24
链与序列区间 作者链 e; PDB构建体 1–70; UniProt 1–70

26S proteasome non-ATPase regulatory subunit 2

物种未注明

UniProt Q13200

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 f; UniProt 1–908 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 121 个其他 PDB 条目、121 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 PSMD2_HUMAN
Isoform
PDB实体 25
链与序列区间 作者链 f; PDB构建体 1–908; UniProt 1–908

Isoform 2 of NEDD8 ultimate buster 1

Homo sapiens

UniProt Q9Y5A7

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 g; UniProt 1–601 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Thioredoxin-like protein 1 × 1 (O43396) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 8 个其他 PDB 条目、8 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 NUB1_HUMAN
Isoform Q9Y5A7-2
PDB实体 26
链与序列区间 作者链 g; PDB构建体 1–601; UniProt 1–601

Thioredoxin-like protein 1

Homo sapiens

UniProt O43396

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 28 PDB 声明:28-meric(28) 与蛋白拷贝数一致 链 u; UniProt 1–289 未记录 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S protease regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S protease regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) Proteasome subunit alpha type-6 × 1 (P60900) Proteasome subunit alpha type-2 × 1 (P25787) Proteasome subunit alpha type-4 × 1 (P25789) Proteasome subunit alpha type-7 × 1 (O14818) Proteasome subunit alpha type-5 × 1 (P28066) Proteasome subunit alpha type-1 × 1 (P25786) Proteasome subunit alpha type-3 × 1 (P25788) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) Isoform 2 of NEDD8 ultimate buster 1 × 1 (Q9Y5A7) substrate peptide × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 4 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ZN ZINC ION × 1 ELECTRON MICROSCOPY cryo-EM缓冲液:pH 7.4;30 mM HEPES pH7.4, 25 mM NaCl, 25 mM KCl, 3% (v/v) glycerol, 5 mM MgCl2 2 mM ATP and 0.5 mM TCEP. cryo-EM玻璃化条件:冷冻剂 ETHANE 分辨率 3.59 Å

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 8 个其他 PDB 条目、8 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 TXNL1_HUMAN
Isoform
PDB实体 27
链与序列区间 作者链 u; PDB构建体 1–289; UniProt 1–289

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

SAXS profile for 9e8l

P(r) 距离分布 P(r) Distribution

P(r) distribution for 9e8l
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2. 结构基本信息 2. Structure Basics

条目编号 entry_id9e8l
沉积日期 deposition_date2024-11-05
结构标题 titleNub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase
关键词 keywords26S Proteasome, Nub1, Fat10, MOTOR PROTEIN, HYDROLASE-PROTEIN BINDING complex; MOTOR PROTEIN, HYDROLASE/PROTEIN BINDING
实验方法 methodELECTRON MICROSCOPY

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier71.36
回转半径 Rg (电子) rg_electron71.07
零角强度 I(0) i013795300000.00
分子量 molecular_weight1004300.0 kDa
排除体积 excluded_volume1260200 ų
包络体积 envelope_volume1929000 ų
水化壳体积 shell_volume216220 ų
包络直径 envelope_diameter230.9
壳层 Rg shell_rg78.98
包络 Rg envelope_rg68.46
形状 Rg shape_rg71.09
总 Rg total_rg71.08
总原子数 total_atoms70522
残基数 n_residues8952
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax258.8
Rg (实空间) rg_real74.22
Rg 误差 (实空间) rg_real_error1.51
I(0) (实空间) i0_real1.3800e+10
I(0) 误差 (实空间) i0_real_error3.0250e+08
Rg (倒空间) rg_reciprocal72.23
I(0) (倒空间) i0_reciprocal13820000000.0000
解质量估计 total_estimate0.9007
解质量评级 solution_quality EXCELLENT a EXCELLENT solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary94.1
偏度 Skewness skewness0.449
峰度 Kurtosis kurtosis0.303
角度范围 angular_range— – 0.1100 −1
当前正则化参数 α current_alpha0.9780
最高正则化参数 α highest_alpha1279000000.0000
实空间数据点数 n_real_points23
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.730; Stabil: 0.893; Sysdev: 1.000; Positv: 1.000; Valcen: 0.934; Smooth: 0.942

5. 晶体学与实验 5. Crystallography & Experiment

6. 实体与聚合物信息 Entities & Polymers (32)

8. 引用文献 (2)

9. 文件与曲线 (10)