SAXSdb — 9rgn

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1. Protein Identity and Related Structures Protein Identity & Related Structures

pH gated chloride channel

Sarcoptes scabiei

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 5	;(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside ; × 5	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A8SDP7_SARSC
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–303； UniProt 28–330 Author chain B； PDBConstruct 1–303； UniProt 28–330 Author chain C； PDBConstruct 1–303； UniProt 28–330 Author chain D； PDBConstruct 1–303； UniProt 28–330 Author chain E； PDBConstruct 1–303； UniProt 28–330

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9rgn
Deposition date deposition_date	2025-06-06
Structure title title	SsCl at pH 6.5 + IVM - Partially opened
Keywords keywords	Ion channel, pLGIC, pH-sensitive channel, Ivermectin, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9rgn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9rgn__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9rgn__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	39.40 Å
Rg (electron density)	38.77 Å
Total Rg	39.25 Å
Atom count	14220
Residues	1655
Excluded volume	256980 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9rgn__assembly_1__model_1`	pentameric （5）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Description description	pH gated chloride channel
Molecular weight formula_weight	39763.9 kDa
Source method src_method	man
Copy count entity_count	5

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E
Atom count atom_count	14256

NNVIIDETFIKTFNKTDRLIRPSFNDKADVIDVSMLIDRFAYYHDIESILEIQAQFEYHWFDQRVKFDCDRSSRIEGNHYHEQIWVPDLRVSRTEDIDVFESENLTRLISIQIDCDGHVRMRFRSNLDLICVMNYQNYPFDEQTCEIELIPSYMEINRLQLRWKDQNIMIRDDFYMSGHLLKGYSVHQKDVELMPYNEIYSALFVHLHLKRQFIYHILVLFLPSIFIVLTSWISFWIEITCIPARVTLCVTTLLAMVTVSKESKQNIPKVPYVKAVDLWFAGCIVSIFITLIEYIFVCYVYRESQPARAASIDRKCRYLIPLAFILFNLIHWS

Source Source

Source organism organism	Sarcoptes scabiei
NCBI taxonomy ID ncbi_taxonomy_id	52283
Host organism host_organism	Spodoptera frugiperda

Entity 2 Entity 2 non-polymer

Description description	;(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside ;
Molecular weight formula_weight	875.1 kDa
Source method src_method	syn
Copy count entity_count	5

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.100 Å
Low-resolution limit resolution_low	134.300 Å
R factor r_factor	0.2830
R_work r_work	0.2830
R_free r_free	—

Resolution resolution	3.10 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	344703

SsCl at pH 6.5 + IVM - Partially opened

1. Protein Identity and Related Structures Protein Identity & Related Structures

pH gated chloride channel

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9rgn__assembly_1__model_1

9rgn__assembly_1__model_1 | I(q)

9rgn__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

7. Citations (1)

SsCl at pH 6.5 + IVM - Partially opened

1. Protein Identity and Related Structures Protein Identity & Related Structures

pH gated chloride channel

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9rgn__assembly_1__model_1

9rgn__assembly_1__model_1 | I(q)

9rgn__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

7. Citations (1)