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9rib

Crystal structure of C278S mutant of mouse CDC14A

Method: X-RAY DIFFRACTION D_max: 106.4 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9rib
deposition_date	2025-06-11
title	Crystal structure of C278S mutant of mouse CDC14A
keywords	CDC14A, DUAL SPECIFICITY PHOSPHATASE, HEARING LOSS, STRUCTURAL-FUNCTIONAL RELATIONSHIP, CELL CYCLE; CELL CYCLE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	30.86 Å
rg_electron	30.50 Å
i0	94895800.00
molecular_weight	78938.0 kDa
excluded_volume	99480 Å³
envelope_volume	121870 Å³
shell_volume	34035 Å³
envelope_diameter	111.1 Å
shell_rg	36.40 Å
envelope_rg	30.68 Å
shape_rg	30.48 Å
total_rg	31.11 Å
total_atoms	11043
n_residues	675
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	106.4 Å
rg_real	30.93 Å
rg_real_error	0.77 Å
i0_real	9.4900e+07
i0_real_error	1.4960e+06
rg_reciprocal	30.90 Å
i0_reciprocal	94890000.0000
total_estimate	0.8720
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	31.3 Å
skewness	0.373
kurtosis	-0.408
angular_range	— – 0.2550 Å⁻¹
current_alpha	0.0000
highest_alpha	28900000.0000
n_real_points	52
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.830; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.865; Smooth: 0.976

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	Dual specificity protein phosphatase CDC14A
formula_weight	39795.5 kDa
ec_number	3.1.3.16,3.1.3.48
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	11769

AAESGELIGACEFMKDRLYFATLRNRPKSTINIHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTSFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTVLDCLQGIRKGLQHGFFDFETFDAEEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKNNVTTIVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHSKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLKEKQASLWVQGDIFRSKLKNR

Source

organism	Mus musculus
common_name	house mouse
ncbi_taxonomy_id	10090
host_organism	Baculovirus expression vector pFastBac1-HM

Entity 2 non-polymer

description	GLYCEROL
formula_weight	92.1 kDa
src_method	syn
entity_count	4

Entity 3 non-polymer

description	SULFATE ION
formula_weight	96.1 kDa
src_method	syn
entity_count	5

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	610

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6. Citations (1)

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length_a	102.507 Å
length_b	158.086 Å
length_c	69.156 Å
angle_alpha	90.00 °
angle_beta	124.56 °
angle_gamma	90.00 °
z_pdb	8

space_group	C 1 2 1
int_tables_number	5
crystal_system	monoclinic

resolution	1.620 Å
resolution_low	28.590 Å
r_factor	0.1670
r_work	0.1647
r_free	0.2097

fit	/app/data/saxs_computation/ri/9rib/9rib.fit
pddf	/app/data/pr_computation/ri/9rib/9rib.pr.out
profile	/app/data/saxs_computation/ri/9rib/9rib.dat

Crystal structure of C278S mutant of mouse CDC14A

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction