Entity 1
polymer
| description | Tyrosine-protein kinase BTK |
| formula_weight | 19966.9 kDa |
| ec_number | 2.7.10.2 |
| src_method | man |
| entity_count | 4 |
Polymer
| type | polypeptide(L) |
| strand_id | A,C,G,J |
| atom_count | 5733 |
AAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPSFWIDGQYLCCSQTAKNAMGCQILEN
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli BL21(DE3) |
Entity 2
non-polymer
| description | (6~{R})-6-(2-bromanyl-6-chloranyl-phenyl)-4-oxidanylidene-6,7-dihydro-5~{H}-1-benzofuran-3-carboxylic acid |
| formula_weight | 369.6 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 3
non-polymer
| description | (6~{R})-6-(2-bromanyl-6-chloranyl-phenyl)-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid |
| formula_weight | 355.6 kDa |
| src_method | syn |
| entity_count | 5 |
Entity 4
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 4 |
Entity 5
non-polymer
| description | ZINC ION |
| formula_weight | 65.4 kDa |
| src_method | syn |
| entity_count | 4 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 265 |