SAXSdb — 9u5c

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1. Structure Basics

entry_id	9u5c
deposition_date	2025-03-21
title	Structure of hTRPC3 in complex with Nb1-94 at 2.25 angstrom
keywords	TRPC3, DAG, Nb1-94, nanobody, METAL TRANSPORT; METAL TRANSPORT
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	50.50 Å
rg_electron	50.40 Å
i0	4122930000.00
molecular_weight	364070.0 kDa
excluded_volume	356580 Å³
envelope_volume	663370 Å³
shell_volume	108620 Å³
envelope_diameter	177.9 Å
shell_rg	55.21 Å
envelope_rg	49.45 Å
shape_rg	50.42 Å
total_rg	50.48 Å
total_atoms	27584
n_residues	3468
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	168.0 Å
rg_real	50.50 Å
rg_real_error	1.29 Å
i0_real	4.1230e+09
i0_real_error	7.6030e+07
rg_reciprocal	50.50 Å
i0_reciprocal	4123000000.0000
total_estimate	0.6227
solution_quality	REASONABLE a REASONABLE solution
n_peaks	1
r_peak_primary	59.6 Å
skewness	0.420
kurtosis	-0.127
angular_range	— – 0.1550 Å⁻¹
current_alpha	0.0000
highest_alpha	212000000.0000
n_real_points	32
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.799; Stabil: 1.000; Sysdev: 0.003; Positv: 1.000; Valcen: 0.997; Smooth: 0.687

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4. Crystallography & Experiment

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5. Entities & Polymer Info (6)

Entity 1 polymer

description	Short transient receptor potential channel 3
formula_weight	96118.2 kDa
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	A,C,E,G
atom_count	27616

MREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	Nb1-94
formula_weight	14058.5 kDa
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	B,D,F,H

QVQLQESGGGSVQSGGSLRLSCAASGYTYSYSGYCMGWFRQAPGKEREGVATIDGAGNTKYADSVKGRFTISRDNAKKTLYLQMNSLKPEDTAMYYCAARVYSYSSDVDCRPSFTTRFPYSGQGTQVTV

Source

organism	Camelus
ncbi_taxonomy_id	9836
host_organism	Escherichia coli

Entity 3 non-polymer

description	CALCIUM ION
formula_weight	40.1 kDa
src_method	syn
entity_count	8

Entity 4 non-polymer

description	ZINC ION
formula_weight	65.4 kDa
src_method	syn
entity_count	4

Entity 5 non-polymer

description	[(2~{S})-2-[(~{E})-octadec-9-enoyl]oxy-3-oxidanyl-propyl] octadec-9-enoate
formula_weight	621.0 kDa
src_method	syn
entity_count	4

Entity 6 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	32

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6. Citations (1)

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resolution	2.25 Å
resolution_method	—
num_particles	254083

fit	/app/data/saxs_computation/u5/9u5c/9u5c.fit
pddf	/app/data/pr_computation/u5/9u5c/9u5c.pr.out
profile	/app/data/saxs_computation/u5/9u5c/9u5c.dat

Structure of hTRPC3 in complex with Nb1-94 at 2.25 angstrom

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

EM 3D

5. Entities & Polymer Info (6)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 non-polymer

Entity 5 non-polymer

Entity 6 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)