crystal structure of the complex of interleukin-31 and its antibody

entry_id	9uk5
deposition_date	2025-04-17
title	crystal structure of the complex of interleukin-31 and its antibody
keywords	cytokine; signaling pathway; interleukin, CYTOKINE/IMMUNE SYSTEM, CYTOKINE-IMMUNE SYSTEM complex; CYTOKINE/IMMUNE SYSTEM
method	X-RAY DIFFRACTION

rg_guinier	29.87 Å
rg_electron	29.74 Å
i0	55941400.00
molecular_weight	59505.0 kDa
excluded_volume	74719 ų
envelope_volume	95212 ų
shell_volume	28773 ų
envelope_diameter	107.4 Å
shell_rg	34.50 Å
envelope_rg	29.76 Å
shape_rg	29.72 Å
total_rg	30.27 Å
total_atoms	4190
n_residues	539
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	103.0 Å
rg_real	30.14 Å
rg_real_error	1.19 Å
i0_real	5.5940e+07
i0_real_error	9.7610e+05
rg_reciprocal	30.03 Å
i0_reciprocal	55940000.0000
total_estimate	0.8446
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	29.1 Å
skewness	0.583
kurtosis	-0.102
angular_range	— – 0.2650 Å−1
current_alpha	0.0000
highest_alpha	9868000.0000
n_real_points	54
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.762; Stabil: 0.996; Sysdev: 1.000; Positv: 1.000; Valcen: 0.808; Smooth: 0.894

Unit Cell

length_a	42.185 Å
length_b	100.801 Å
length_c	128.615 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

Symmetry

space_group	P 21 21 21
int_tables_number	19
crystal_system	orthorhombic

Refinement

resolution	1.900 Å
resolution_low	35.270 Å
r_factor	0.2031
r_work	0.2011
r_free	0.2391

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/uk/9uk5/pr_distribution.json
• pr_output /app/data/pr_computation/uk/9uk5/9uk5.pr.out
• pr_plot /app/data/visualization/pr_computation/uk/9uk5/9uk5_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/uk/9uk5/9uk5.dat
• saxs_fit /app/data/saxs_computation/uk/9uk5/9uk5.fit
• saxs_log /app/data/saxs_computation/uk/9uk5/9uk5.log
• saxs_plot /app/data/visualization/saxs_computation/uk/9uk5/9uk5_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/uk/9uk5/9uk5.fit
pddf	/app/data/pr_computation/uk/9uk5/9uk5.pr.out
profile	/app/data/saxs_computation/uk/9uk5/9uk5.dat