← Back to search
← Back to search
9uwl

Cryo-EM structure of human V1aR bound with SRX246 at a resolution of 2.6 angstrom

Method: ELECTRON MICROSCOPY Dmax: 89.0 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9uwl

P(r) Distribution

P(r) distribution for 9uwl
▼

1. Structure Basics

entry_id9uwl
deposition_date2025-05-12
titleCryo-EM structure of human V1aR bound with SRX246 at a resolution of 2.6 angstrom
keywordsGPCR, small molecule, antagonist, nanobody, SIGNALING PROTEIN; SIGNALING PROTEIN
methodELECTRON MICROSCOPY
▼

Download Data

▼

2. SAXS Parameters (CRYSOL)

rg_guinier28.69 Å
rg_electron27.67 Å
i052402300.00
molecular_weight63607.0 kDa
excluded_volume82471 ų
envelope_volume96885 ų
shell_volume29017 ų
envelope_diameter90.5 Å
shell_rg34.57 Å
envelope_rg28.04 Å
shape_rg27.65 Å
total_rg28.50 Å
total_atoms9066
n_residues530
n_harmonics20
q_range— – 0.5000 Å−1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3
▼

3. P(r) Analysis (GNOM)

dmax89.0 Å
rg_real28.66 Å
rg_real_error0.56 Å
i0_real5.2400e+07
i0_real_error7.6270e+05
rg_reciprocal28.67 Å
i0_reciprocal52400000.0000
total_estimate0.9043
solution_quality EXCELLENT a EXCELLENT solution
n_peaks3
r_peak_primary27.5 Å
skewness0.199
kurtosis-0.639
angular_range— – 0.2750 Å−1
current_alpha0.0000
highest_alpha9919000.0000
n_real_points56
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.961; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.975; Smooth: 0.894
▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (4)

▶

6. Citations (1)

▶

7. Files & Curves (10)