9vuk

Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein

Measles virus genotype A-vaccine

UniProt P0AEX9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MALE_ECOLI
Isoform —
PDB entities 1, 2
Chains and sequence ranges Author chain A; PDBConstruct 15–378; UniProt 29–392 Author chain B; PDBConstruct 15–378; UniProt 29–392 Author chain C; PDBConstruct 15–378; UniProt 29–392 Author chain D; PDBConstruct 15–378; UniProt 29–392 Author chain L; PDBConstruct 15–378; UniProt 29–392

Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein

Measles virus genotype A-vaccine

UniProt P35974

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Maltose/maltodextrin-binding periplasmic protein,RNA-directed RNA polymerase L,Strep II and FLAG tag × 1 (P0AEX9,P35975) ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PHOSP_MEASA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 399–602; UniProt 304–507 Author chain B; PDBConstruct 399–602; UniProt 304–507 Author chain C; PDBConstruct 399–602; UniProt 304–507 Author chain D; PDBConstruct 399–602; UniProt 304–507

Maltose/maltodextrin-binding periplasmic protein,RNA-directed RNA polymerase L,Strep II and FLAG tag

synthetic construct

UniProt P35975

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein × 4 (P0AEX9,P35974) ZINC ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name L_MEASA
Isoform —
PDB entities 2
Chains and sequence ranges Author chain L; PDBConstruct 399–2581; UniProt 1–2183

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9vuk
Deposition date deposition_date2025-07-13
Structure title titleCryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex
Keywords keywordsMeasles virus RNA-dependent RNA polymerase complex, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9vuk__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9vuk__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9vuk__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)37.62 Å
Rg (electron density)36.94 Å
Total Rg37.56 Å
Atom count12103
Residues1519
Excluded volume217340 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9vuk__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)