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9wji

Alkylsulfone-bound human VAChT

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPins

synthetic construct

UniProt P0AEX9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Monomer Protein 1 2-(3-ethylsulfonylpyridin-2-yl)-3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridine × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2d21 2h25 2klf 2mv0 2n44 2n45 3csb 3csg 3kjt 5aq9 5aq9 5gxt

18 assemblies; showing the first 12

Homodimer
2obg

1 assemblies

Homotetramer

None

Other homooligomers
9wy8

1 assemblies

Heteromeric or nucleic-acid complex
21dh 21dh 21dh 21dh 21dh 21dh 2ok2 2r6g 2zxt 3a3c 3c4m 3c4m

472 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name MALE_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–364； UniProt 29–391

Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPins

synthetic construct

UniProt Q16572

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Monomer Protein 1 2-(3-ethylsulfonylpyridin-2-yl)-3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridine × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
8xtw 8xtx 8xty 8zmr 8zms 9kkn 9kko 9kq5 9kqm 9wjh 9wji

11 assemblies

View Construct and Data Evidence
UniProt name VACHT_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 379–869； UniProt 34–524

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9wji
Deposition date deposition_date2025-08-31
Structure title titleAlkylsulfone-bound human VAChT
Keywords keywordsVAChT, SLC18A3, Acetylcholine, Alkylsulfone, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9wji__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9wji__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9wji__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）21.34 Å
Rg (electron density)20.40 Å
Total Rg21.43 Å
Atom count3003
Residues394
Excluded volume55015 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9wji__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)