Current Protein Identity:A4IJK8
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5EUL Structure of the SecA-SecY complex with a translocating polypeptide substrate Deposited 2015-11-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Not recorded | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 TBR HEXATANTALUM DODECABROMIDE × 18 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;21-24% polyethylene glycol 1500, 100mM Tris-HCl pH8.5, 50-100 mM MgAc2, 2% 2-methyl-2,4-pentandiol
|
Resolution 3.70 Å R-free 0.315 |
| 6ITC Structure of a substrate engaged SecA-SecY protein translocation machine Deposited 2018-11-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C,Q202T,L210G,F211G,R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.45 Å |
| 7XHA Structure of the SecA/SecYE/proOmpA(4Y)-sfGFP complex with ADP.BeF3-. Deposited 2022-04-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.35 Å |
| 7XHB Structure of the SecA/SecYE/proOmpA(4Y)-sfGFP complex with ADP Deposited 2022-04-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.33 Å |
| 8Y9Y Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+1C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C, Q202T, F211T, R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.29 Å |
| 8Y9Z Structure of the SecA-SecY complex with the substrate HmBRI-3TM Deposited 2024-02-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C, Q202T, F211T, R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.41 Å |
| 8YA0 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain Y
2–430(429 aa)
|
Mutation:G60C, Q202T, F211T, R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.97 Å |
| 8YA2 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+20C) Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C, Q202T, F211T, R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.84 Å |
| 8YA3 Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) treated with DTT Deposited 2024-02-07 | Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C, Q202T, F211T, R213N | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.27 Å |
| 8YAS Structure of the SecA-SecY complex with the substrate HmBRI-7TM Deposited 2024-02-10 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain Y
1–430(430 aa)
|
Mutation:G60C, Q202T, F211T, R213N | MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.97 Å |