Current Protein Identity:G1TS40
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4KZX Rabbit 40S ribosomal subunit in complex with eIF1. Deposited 2013-05-30 | Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 35-meric(35) Consistent with all polymers |
Chain Y
1–133(133 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
|
Resolution 7.81 Å R-free 0.347 |
| 4KZY Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. Deposited 2013-05-30 | Assembly 1 Protein–RNA Heteromer;Protein × 35 PDB declaration: 36-meric(36) Consistent with all polymers |
Chain Y
1–133(133 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
|
Resolution 7.01 Å R-free 0.348 |
| 4KZZ Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A Deposited 2013-05-30 | Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 37-meric(37) Consistent with all polymers |
Chain Y
1–133(133 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 8.5;292 K;0.1M Ammonium acetate, 0.05M Tris-HCl pH 8.5, 2.5% PEG-20K, 4-6% MPD, 5.0mM Mg acetate, 2.0mM TCEP, vapor diffusion, temperature 292K
|
Resolution 7.03 Å R-free 0.359 |
| 5K0Y m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face Deposited 2016-05-17 | Assembly 1 Protein–RNA Heteromer;Protein × 39 PDB declaration: 42-meric(42) Consistent with all polymers |
Chain s
3–133(131 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.80 Å |
| 6YAL Mammalian 48S late-stage initiation complex with beta-globin mRNA Deposited 2020-03-12 | Assembly 1 Protein–RNA Heteromer;Protein × 38 PDB declaration: 41-meric(41) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 2 MG MAGNESIUM ION × 1 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å |
| 6YAM Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA Deposited 2020-03-12 | Assembly 1 Protein–RNA Heteromer;Protein × 47 PDB declaration: 50-meric(50) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 2 MG MAGNESIUM ION × 1 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 6YAN Mammalian 48S late-stage translation initiation complex with histone 4 mRNA Deposited 2020-03-12 | Assembly 1 Protein–RNA Heteromer;Protein × 36 PDB declaration: 39-meric(39) Consistent with all polymers |
Chain a
3–128(126 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.48 Å |
| 8P03 48S late-stage initiation complex with m6A mRNA Deposited 2023-05-09 | Assembly 1 Protein–RNA Heteromer;Protein × 37 PDB declaration: 40-meric(40) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | MG MAGNESIUM ION × 178 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.04 Å |
| 8P09 48S late-stage initiation complex with non methylated mRNA Deposited 2023-05-09 | Assembly 1 Protein–RNA Heteromer;Protein × 37 PDB declaration: 40-meric(40) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | MG MAGNESIUM ION × 230 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 9CPA Structure of a Mammalian DHX29-bound 43S Pre-initiation Complex Deposited 2024-07-18 | Assembly 1 Protein–RNA Heteromer;Protein × 49 PDB declaration: 51-meric(51) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 6.00 Å |
| 9H6Y Late-stage 48S Initiation Complex (LS48S IC) guided by the trans-RNA Deposited 2024-10-25 | Assembly 1 Protein–RNA Heteromer;Protein × 39 PDB declaration: 42-meric(42) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;10 mM HEPES-KOH pH 7.4, 5 mM Mg(OAc)2, 50 mM KOAc, 10 mM NH4Cl, 2 mM DTT and Roche cOmplete protease inhibitor cocktail
cryo-EM vitrification conditions
Cryogen ETHANE;The sample was incubated on the grid for 30 s and then blotted with filter paper from both sides for 1.5 s with the blot force 5
|
Resolution 2.90 Å |
| 9H74 Late-stage 48S Initiation Complex with eIF3 (LS48S-eIF3 IC) guided by the trans-RNA Deposited 2024-10-25 | Assembly 1 Protein–RNA Heteromer;Protein × 48 PDB declaration: 51-meric(51) Consistent with all polymers |
Chain a
1–133(133 aa)
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;10 mM HEPES-KOH pH 7.4, 5 mM Mg(OAc)2, 50 mM KOAc, 10 mM NH4Cl, 2 mM DTT and Roche cOmplete protease inhibitor cocktail
cryo-EM vitrification conditions
Cryogen ETHANE;The sample was incubated on the grid for 30 s and then blotted with filter paper from both sides for 1.5 s with the blot force 5
|
Resolution 2.90 Å |
| 9UZK EMCV IRES captured on mammalian 40S with initiator tRNA Deposited 2025-05-16 | Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 37-meric(37) Consistent with all polymers |
Chain a
3–128(126 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;20mM HEPES, 150mM KOAc, 2mM MgCl2, 1mM DTT, 0.5mM Spermidine, 6mM GMP-PnP
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 4.60 Å |
| 9UZL EMCV IRES captured on mammalian 40S ribosome with initiator tRNA and eIF2 Deposited 2025-05-16 | Assembly 1 Protein–RNA Heteromer;Protein × 36 PDB declaration: 39-meric(39) Consistent with all polymers |
Chain a
3–128(126 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;20mM HEPES, 150mM KOAc, 2mM MgCl2, 1mM DTT, 0.5mM Spermidine, 6mM GMP-PnP
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 5.01 Å |
| 9UZM 40S ribosome without initiation factors Deposited 2025-05-16 | Assembly 1 Protein–RNA Heteromer;Protein × 34 PDB declaration: 35-meric(35) Consistent with all polymers |
Chain a
3–128(126 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;20mM HEPES, 150mM KOAc, 2mM MgCl2, 1mM DTT, 0.5mM Spermidine, 6mM GMP-PnP
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 4.50 Å |