← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：O43189 New Search
9PDB entries
36Biological assembly
51chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2E5P Solution structure of the TUDOR domain of PHD finger protein 1 (PHF1 protein) Deposited 2006-12-22 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 29–83（55 aa） Fragment：TUDOR domain, residues 8-62
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 20mM d-Tris-HCl(pH 7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O, 90% H2O | 90% H2O/10% D2O
Resolution not provided
2M0O The solution structure of human PHF1 in complex with H3K36me3 Deposited 2012-10-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 6–83（78 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 50；Pressure ambient
NMR sample composition 0.3-0.5 mM [U-100% 13C; U-100% 15N] PHF1 tudor, 0.6-1.0 mM H3K36me3 peptide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
4HCZ PHF1 Tudor in complex with H3K36me3 Deposited 2012-10-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 28–85（58 aa） Fragment：Tudor domain
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.15 K；0.1 M HEPES pH 7.5, 20% PEG 10000, VAPOR DIFFUSION, SITTING DROP, temperature 277.15K
Resolution 1.85 Å R-free 0.244
4HCZ PHF1 Tudor in complex with H3K36me3 Deposited 2012-10-01 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 28–85（58 aa） Fragment：Tudor domain
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.15 K；0.1 M HEPES pH 7.5, 20% PEG 10000, VAPOR DIFFUSION, SITTING DROP, temperature 277.15K
Resolution 1.85 Å R-free 0.244
5XFN Structure of the N-terminal domains of PHF1 Deposited 2017-04-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 25–340（316 aa） Fragment：UNP residues 25-340
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1 M Tris-pH 8.0, 10% PEG 3350, 22% ethylene glycerol
Resolution 1.90 Å R-free 0.218
5XFO Structure of the N-terminal domains of PHF1 Deposited 2017-04-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 25–340（316 aa） Fragment：UNP residues 25-340
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1M Tris-pH 8.0, 10% PEG 3350, 22% ethylene glycerol
Resolution 1.90 Å R-free 0.227
5XFP Binary complex of PHF1 and a double stranded DNA Deposited 2017-04-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 25–360（336 aa） Fragment：UNP residues 25-360
Not recorded ZN ZINC ION × 4 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1M Tris-pH 8.5, 25% PEG 3350, 0.2M Li2SO4, 10mM MgCl2
Resolution 2.30 Å R-free 0.244
5XFP Binary complex of PHF1 and a double stranded DNA Deposited 2017-04-11 Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain B 25–360（336 aa） Fragment：UNP residues 25-360
Not recorded ZN ZINC ION × 4 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1M Tris-pH 8.5, 25% PEG 3350, 0.2M Li2SO4, 10mM MgCl2
Resolution 2.30 Å R-free 0.244
5XFP Binary complex of PHF1 and a double stranded DNA Deposited 2017-04-11 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 25–360（336 aa） Fragment：UNP residues 25-360
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1M Tris-pH 8.5, 25% PEG 3350, 0.2M Li2SO4, 10mM MgCl2
Resolution 2.30 Å R-free 0.244
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain AA 28–87（60 aa）
Chain AC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 10 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain JA 28–87（60 aa）
Chain JC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 10 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 11 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain KA 28–87（60 aa）
Chain KC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 12 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain LA 28–87（60 aa）
Chain LC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 13 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain MA 28–87（60 aa）
Chain MC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 14 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain NA 28–87（60 aa）
Chain NC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 15 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain OA 28–87（60 aa）
Chain OC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain BA 28–87（60 aa）
Chain BC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 3 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain CA 28–87（60 aa）
Chain CC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 15 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 4 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain DA 28–87（60 aa）
Chain DC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 5 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain EA 28–87（60 aa）
Chain EC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 18 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 6 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain FA 28–87（60 aa）
Chain FC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 7 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain GA 28–87（60 aa）
Chain GC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 8 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain HA 28–87（60 aa）
Chain HC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 15 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAT complex structure of PHF1 Deposited 2020-03-26 Assembly 9 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain IA 28–87（60 aa）
Chain IC 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；2.4M ammonium phosphate dibasic and 0.1M HEPES pH7.0
Resolution 1.80 Å R-free 0.268
6WAV Crystal structure of PHF1 in complex with H3K36me3 substitution Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 28–87（60 aa）
Not recorded SO4 SULFATE ION × 1 UNX UNKNOWN LIGAND × 17 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；291 K；1.2 M ammonium sulfate and 0.1 M sodium acetate 4.6
Resolution 1.70 Å R-free 0.241
6WAV Crystal structure of PHF1 in complex with H3K36me3 substitution Deposited 2020-03-26 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；291 K；1.2 M ammonium sulfate and 0.1 M sodium acetate 4.6
Resolution 1.70 Å R-free 0.241
6WAV Crystal structure of PHF1 in complex with H3K36me3 substitution Deposited 2020-03-26 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；291 K；1.2 M ammonium sulfate and 0.1 M sodium acetate 4.6
Resolution 1.70 Å R-free 0.241
6WAV Crystal structure of PHF1 in complex with H3K36me3 substitution Deposited 2020-03-26 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 28–87（60 aa）
Not recorded UNX UNKNOWN LIGAND × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；291 K；1.2 M ammonium sulfate and 0.1 M sodium acetate 4.6
Resolution 1.70 Å R-free 0.241
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 28–87（60 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 28–87（60 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 28–87（60 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 28–87（60 aa）
Not recorded ZN ZINC ION × 1 DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 28–87（60 aa）
Not recorded ZN ZINC ION × 1 DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 28–87（60 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 7 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 28–87（60 aa）
Not recorded DMS DIMETHYL SULFOXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281
7LKY Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Deposited 2021-02-03 Assembly 8 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain H 28–87（60 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277.15 K；0.01 M ZnCl2, 0.1 M MES pH 6.0 and 20% PEG 6000
Resolution 1.85 Å R-free 0.281

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.