Current Protein Identity：O43521
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1F95 SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX Deposited 2000-07-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
108–116（9 aa）
Fragment：DLC8 BINDING REGION
Chain D
108–116（9 aa）
Fragment：DLC8 BINDING REGION
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 100mM；Pressure ambient
NMR sample composition
1.5mM DLC8/Bim peptide complex 15N; 100mM phosphate buffer; 10mM DTT; 90% H2O and 10% D2O | 90% H2O and 10% D2O
NMR sample composition
1.5mM DLC8/Bim peptide complex 15N,13C; 100mM phosphate buffer; 10mM DTT; 90% H2O and 10% D2O | 90% H2O and 10% D2O
NMR sample composition
1.5mM DLC8/Bim peptide complex ; 100mM phosphate buffer; 10mM DTT; 99.9% D2O | 99.9% D2O
|
Resolution not provided |
| 2K7W BAX Activation is Initiated at a Novel Interaction Site Deposited 2008-08-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
145–164（20 aa）
Fragment：BIM BH3 domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6；305 K；Ionic strength (raw mmCIF value) 50；Pressure ambient
NMR sample composition
0.1-0.2 mM [U-99% 15N] protein, 0.1-0.2 mM peptide, 90% H2O/10%D20 | 90% H2O/10%D20
|
Resolution not provided |
| 2NL9 Crystal structure of the Mcl-1:Bim BH3 complex Deposited 2006-10-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | ZN ZINC ION × 7 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；298 K；0.2M zinc acetate, 0.2M imidazole, 2mM TCEP, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.55 Å R-free 0.203 |
| 2NL9 Crystal structure of the Mcl-1:Bim BH3 complex Deposited 2006-10-19 | Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | ZN ZINC ION × 28 CL CHLORIDE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；298 K；0.2M zinc acetate, 0.2M imidazole, 2mM TCEP, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.55 Å R-free 0.203 |
| 2NL9 Crystal structure of the Mcl-1:Bim BH3 complex Deposited 2006-10-19 | Assembly 3 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | ZN ZINC ION × 28 CL CHLORIDE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；298 K；0.2M zinc acetate, 0.2M imidazole, 2mM TCEP, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.55 Å R-free 0.203 |
| 2V6Q Crystal Structure of a BHRF-1 : Bim BH3 complex Deposited 2007-07-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：RESIDUES 141-166
|
Not recorded | BR BROMIDE ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 4；0.1 M MALIC ACID PH 4.0, 1.7 M NABR, 0.1 M GUANIDINE HCL
|
Resolution 2.70 Å R-free 0.249 |
| 2VM6 Human Bcl2-A1 in complex with Bim-BH3 peptide Deposited 2008-01-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–165（25 aa）
Fragment：RESIDUES 141-165
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.8；293 K；0.1M BIS, TRIS PH 5.8, 2M AMSO4
|
Resolution 2.20 Å R-free 0.250 |
| 2WH6 Crystal structure of anti-apoptotic BHRF1 in complex with the Bim BH3 domain Deposited 2009-05-01 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
51–76（26 aa）
Fragment：BH3, RESIDUES 51-72
|
Not recorded | BR BROMIDE ION × 9 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 4；0.1 M MALIC ACID PH 4 1.25 M NABR
|
Resolution 1.50 Å R-free 0.205 |
| 2YQ6 Structure of Bcl-xL bound to BimSAHB Deposited 2012-11-06 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
147–164（18 aa）
Fragment：BH3 DOMAIN, RESIDUES 14-31
|
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) | GOL GLYCEROL × 14 | X-RAY DIFFRACTION |
X-ray crystallization conditions
15 % (W/V) PEG 400, 5 % PEG 3000, 10 % GLYCEROL AND 0.1 M MES PH 6.5.
|
Resolution 1.80 Å R-free 0.201 |
| 2YQ7 Structure of Bcl-xL bound to BimLOCK Deposited 2012-11-06 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
147–164（18 aa）
Fragment：BH3 DOMAIN, RESIDUES 147-164
|
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) | GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
15 % (W/V) PEG 400, 5 % PEG 3000, 10 % GLYCEROL AND 0.1 M MES PH 6.5.
|
Resolution 1.90 Å R-free 0.208 |
| 3D7V Crystal structure of Mcl-1 in complex with an Mcl-1 selective BH3 ligand Deposited 2008-05-22 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：Bim BH3
|
Mutation：L62A, F69A | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；298 K；0.2M Zinc Acetate, 0.2M Imidazole, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.03 Å R-free 0.241 |
| 3FDL Bim BH3 peptide in complex with Bcl-xL Deposited 2008-11-26 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3 domain, UNP residues 141-166
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；1M Sodium citrate, 0.1M Sodium cacodylate, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.78 Å R-free 0.208 |
| 3FDL Bim BH3 peptide in complex with Bcl-xL Deposited 2008-11-26 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3 domain, UNP residues 141-166
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；1M Sodium citrate, 0.1M Sodium cacodylate, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.78 Å R-free 0.208 |
| 3IO8 BimL12F in complex with Bcl-xL Deposited 2009-08-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3 peptide, residues 141-166
|
Mutation：L152P | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.02M Zinc Acetate
2.5M Sodium Chloride
0.1M Imidazole, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.30 Å R-free 0.231 |
| 3IO8 BimL12F in complex with Bcl-xL Deposited 2009-08-14 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
141–166（26 aa）
Fragment：BH3 peptide, residues 141-166
|
Mutation：L152P | ZN ZINC ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.02M Zinc Acetate
2.5M Sodium Chloride
0.1M Imidazole, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.30 Å R-free 0.231 |
| 3IO9 BimL12Y in complex with Mcl-1 Deposited 2009-08-14 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3 peptide, residues 141-166
|
Mutation：L152P | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；298 K；0.15M zinc acetate, 0.15 M imidizole, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.40 Å R-free 0.251 |
| 3KJ0 Mcl-1 in complex with Bim BH3 mutant I2dY Deposited 2009-11-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
143–165（23 aa）
Fragment：BH3 region of BIM (UNP 1-23)
|
Mutation：I6Y | TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；0.1 M Tris, 45% MPD, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.70 Å R-free 0.224 |
| 3KJ1 Mcl-1 in complex with Bim BH3 mutant I2dA Deposited 2009-11-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
143–163（21 aa）
Fragment：BH3 region of BIM (UNP 1-21)
|
Mutation：I6A | ZN ZINC ION × 5 ACT ACETATE ION × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Imidazole, 0.2 M Zinc Acetate, 16% PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.95 Å R-free 0.213 |
| 3KJ1 Mcl-1 in complex with Bim BH3 mutant I2dA Deposited 2009-11-02 | Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain B
143–163（21 aa）
Fragment：BH3 region of BIM (UNP 1-21)
|
Mutation：I6A | ZN ZINC ION × 20 ACT ACETATE ION × 4 CL CHLORIDE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Imidazole, 0.2 M Zinc Acetate, 16% PEG 400, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.95 Å R-free 0.213 |
| 3KJ2 Mcl-1 in complex with Bim BH3 mutant F4aE Deposited 2009-11-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
143–163（21 aa）
Fragment：BH3 region of Bim (UNP 1-21)
|
Mutation：F17E | ZN ZINC ION × 4 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Imidazole, 0.2 M Zinc Acetate, 2% PEG 3350, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.35 Å R-free 0.247 |
| 3KJ2 Mcl-1 in complex with Bim BH3 mutant F4aE Deposited 2009-11-02 | Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain B
143–163（21 aa）
Fragment：BH3 region of Bim (UNP 1-21)
|
Mutation：F17E | ZN ZINC ION × 16 ACT ACETATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；0.1 M Imidazole, 0.2 M Zinc Acetate, 2% PEG 3350, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.35 Å R-free 0.247 |
| 4B4S Crystal Structure of a pro-survival Bcl-2:Bim BH3 complex Deposited 2012-08-01 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
51–76（26 aa）
Fragment：RESIDUES 51-76
|
Not recorded | PG4 TETRAETHYLENE GLYCOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8；0.1 M MGCL2, 20 % PEG 400, 20 % PEG 3350, 0.1 M TRIS PH 8.0
|
Resolution 1.90 Å R-free 0.220 |
| 4D2M Vaccinia Virus F1L bound to Bim BH3 Deposited 2014-05-12 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：RESIDUES 141-166
Chain D
141–166（26 aa）
Fragment：RESIDUES 141-166
|
Not recorded | MRD (4R)-2-METHYLPENTANE-2,4-DIOL × 2 CL CHLORIDE ION × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.2；0.2M KCL, 15 % PEG400, 1.44 % MPD AND 0.1M AMMONIUM CITRATE PH 6.2.
|
Resolution 2.10 Å R-free 0.255 |
| 4QVF Crystal structure of Bcl-xL in complex with BIM BH3 domain Deposited 2014-07-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；291 K；17.5% PEG 8000, 0.2M NaCl, 0.1M phosphate citrate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.53 Å R-free 0.230 |
| 4UF3 Deerpox virus DPV022 in complex with Bim BH3 Deposited 2014-12-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3, UNP RESIDUES 141-166
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.5；17% PEG 8000, 0.2M MES PH 5.5, 0.2M AMMONIUM SULPHATE
|
Resolution 2.70 Å R-free 0.221 |
| 4ZIE Crystal Structure of core/latch dimer of Bax in complex with BimBH3 Deposited 2015-04-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
141–166（26 aa）
Fragment：BH3 motif, UNP RESIDUES 141-166
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 9；277 K；PEG6000, bicine
|
Resolution 1.80 Å R-free 0.229 |
| 4ZIF Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini Deposited 2015-04-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–160（20 aa）
Fragment：BH3 motif, unp residues 141-160
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；Tri-sodium citrate, Sodium cacodylate
|
Resolution 2.40 Å R-free 0.255 |
| 4ZIH Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini Deposited 2015-04-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–160（20 aa）
Fragment：BH3 motif, unp residues 141-160
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；Tri-sodium citrate, Sodium cacodylate
|
Resolution 2.50 Å R-free 0.233 |
| 5AGW Bcl-2 alpha beta-1 complex Deposited 2015-02-04 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
146–166（21 aa）
Fragment：RESIDUES 148-166
|
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；0.02M CACL2, 0.1M MOPS PH7.0, 10% 2-PROPANOL
|
Resolution 2.69 Å R-free 0.272 |
| 5AGW Bcl-2 alpha beta-1 complex Deposited 2015-02-04 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
146–166（21 aa）
Fragment：RESIDUES 148-166
|
Mutation：YES Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；0.02M CACL2, 0.1M MOPS PH7.0, 10% 2-PROPANOL
|
Resolution 2.69 Å R-free 0.272 |
| 5AGX Bcl-2 alpha beta-1 LINEAR complex Deposited 2015-02-04 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
146–166（21 aa）
Fragment：BIM BH3, RESIDUES 146-166
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；PH 7.0
|
Resolution 2.24 Å R-free 0.245 |
| 5AGX Bcl-2 alpha beta-1 LINEAR complex Deposited 2015-02-04 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
146–166（21 aa）
Fragment：BIM BH3, RESIDUES 146-166
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7；PH 7.0
|
Resolution 2.24 Å R-free 0.245 |
| 5C3G Crystal structure of Bcl-xl bound to BIM-MM Deposited 2015-06-17 | Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
56–76（21 aa）
Fragment：UNP residues 56-76
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；12% Peg 1500, 0.1M Sodium Acetate pH 5.5, 2.5M NaCl, 1.5% MPD
|
Resolution 2.45 Å R-free 0.274 |
| 5VWV Bak core latch dimer in complex with Bim-BH3 - Cubic Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–165（25 aa）
Fragment：UNP residues 141-165
|
Mutation：W147R, Y163T | TFA trifluoroacetic acid × 1 EDO 1,2-ETHANEDIOL × 6 CL CHLORIDE ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；281 K；18 % glycerol, 21.6 % PEG (poly-ethylene glycol) 1500 and 0.5 % ethyl acetate
|
Resolution 1.90 Å R-free 0.177 |
| 5VWV Bak core latch dimer in complex with Bim-BH3 - Cubic Deposited 2017-05-23 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–165（25 aa）
Fragment：UNP residues 141-165
|
Mutation：W147R, Y163T | TFA trifluoroacetic acid × 2 EDO 1,2-ETHANEDIOL × 12 CL CHLORIDE ION × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；281 K；18 % glycerol, 21.6 % PEG (poly-ethylene glycol) 1500 and 0.5 % ethyl acetate
|
Resolution 1.90 Å R-free 0.177 |
| 5VWW Bak core latch dimer in complex with Bim-RT - Tetragonal Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
141–166（26 aa）
Fragment：UNP residues 141-166
Chain D
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Mutation：W147R, Y163T | MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 BR BROMIDE ION × 2 IMD IMIDAZOLE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；281 K；12.5 % MPD (2-methyl-2,4-pentanediol), 38 mM imidazole pH 6.5, 12.5 % PEG 1000, 12.5 % PEG 3350, 30 mM sodium fluoride, 30 mM sodium iodide, 62 mM sodium MES pH 6.5 and 30 mM sodium bromide
|
Resolution 2.80 Å R-free 0.281 |
| 5VWX Bak core latch dimer in complex with Bim-h0-h3Glt Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
142–164（23 aa）
Fragment：UNP residues 142-164
Chain D
142–164（23 aa）
Fragment：UNP residues 142-164
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5；281 K；200 mM calcium acetate, 30 % PEG 400 and 100 mM sodium acetate-acetic acid pH 5.0
|
Resolution 2.49 Å R-free 0.305 |
| 5VWY Bak core latch dimer in complex with Bim-h3Pc-RT Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；277 K；15.8 % PEG 8000, 50 mM potassium dihydrogen phosphate, and 22.7 % glycerol
|
Resolution 1.55 Å R-free 0.216 |
| 5VWZ Bak in complex with Bim-h3Pc Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
Chain D
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | 1PG 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL × 2 NH4 AMMONIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；281 K；10 % PEG 20000, 20 % PEG MME 550, 38 mM Imidazole pH 6.5, 20 mM ammonium acetate, 20 mM potassium sodium tartrate, 20 mM sodium formate, 62 mM sodium MES pH 6.5, 20 mM trisodium citrate, and 20 mM sodium oxamate
|
Resolution 1.62 Å R-free 0.191 |
| 5VX0 Bak in complex with Bim-h3Glg Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
Chain D
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 6 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；281 K；200 mM magnesium chloride, 25 % PEG 3350, and 100 mM bis-tris chloride (pH 6.5)
|
Resolution 1.60 Å R-free 0.200 |
| 5VX2 Mcl-1 in complex with Bim-h3Pc-RT Deposited 2017-05-23 | Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
Chain D
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；281 K；20 % PEG 3000, 100 mM trisodium citrate buffered with citric acid pH 5.5
|
Resolution 1.85 Å R-free 0.210 |
| 5VX3 Bcl-xL in complex with Bim-h3Pc-RT Deposited 2017-05-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：UNP residues 141-166
Chain F
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；273 K；200 mM magnesium chloride, 20 % PEG 6000, and 100 mM sodium MES pH 6
|
Resolution 1.95 Å R-free 0.243 |
| 5VX3 Bcl-xL in complex with Bim-h3Pc-RT Deposited 2017-05-23 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain D
141–166（26 aa）
Fragment：UNP residues 141-166
Chain H
141–166（26 aa）
Fragment：UNP residues 141-166
|
Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：W147R, Y163T Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；273 K；200 mM magnesium chloride, 20 % PEG 6000, and 100 mM sodium MES pH 6
|
Resolution 1.95 Å R-free 0.243 |
| 5WOS Structural and functional insights into Canarypox Virus CNP058 regulation of apoptosis Deposited 2017-08-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
Fragment：BH3 domain (UNP residues 141-166)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6；293 K；0.2 M calcium chloride dihydrate, 0.1 M MES pH 6.0, 20% w/v PEG6000
|
Resolution 2.45 Å R-free 0.245 |
| 6QFI Structure of human Mcl-1 in complex with BIM BH3 peptide Deposited 2019-01-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.75；293 K；0.2M zinc acetate, 0.2M Imidazole pH 5.75
|
Resolution 2.40 Å R-free 0.236 |
| 6RJP Bfl-1 in complex with alpha helical peptide Deposited 2019-04-29 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
147–163（17 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；293 K；0.1 M sodium acetate pH 4.6
16% (w/v) PEG smear high
|
Resolution 2.57 Å R-free 0.266 |
| 6RJP Bfl-1 in complex with alpha helical peptide Deposited 2019-04-29 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
147–163（17 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；293 K；0.1 M sodium acetate pH 4.6
16% (w/v) PEG smear high
|
Resolution 2.57 Å R-free 0.266 |
| 6TQQ Structural insight into tanapoxvirus mediated inhibition of apoptosis Deposited 2019-12-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | NA SODIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M MIB pH 8.0, 25% PEG 1500
|
Resolution 3.00 Å R-free 0.276 |
| 6X8O BimBH3 peptide tetramer Deposited 2020-06-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
141–166（26 aa）
Chain B
141–166（26 aa）
Chain C
141–166（26 aa）
Chain D
141–166（26 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | SCN THIOCYANATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；20% PEG600, 0.05 M Tris-HCl, 0.15 M potassium thiocyanate, 0.5% CHAPS
|
Resolution 1.31 Å R-free 0.168 |
| 8T5E De novo design of high-affinity protein binders to bioactive helical peptides Deposited 2023-06-13 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
141–166（26 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4；293 K；0.1 M Citric acid pH 2.5, 20% (w/v) PEG 6000
|
Resolution 3.00 Å R-free 0.264 |