Current Protein Identity：P03120
New Search
Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1BY9 CRYSTAL STRUCTURE OF THE E2 DNA-BINDING DOMAIN FROM HUMAN PAPILLOMAVIRUS TYPE-16: IMPLICATIONS FOR ITS DNA BINDING-SITE SELECTION MECHANISM Deposited 1998-10-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
285–365（81 aa）
Fragment：DNA-BINDING DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.2；pH 6.2
|
Resolution 2.20 Å R-free 0.220 |
| 1DTO CRYSTAL STRUCTURE OF THE COMPLETE TRANSACTIVATION DOMAIN OF E2 PROTEIN FROM THE HUMAN PAPILLOMAVIRUS TYPE 16 Deposited 2000-01-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–201（201 aa）
Fragment：TRANSACTIVATION DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.3；291 K；monomethylether PEG 5000, NaCl, isopropanol, triethanolamine,Tris-HCl, DTT, EDTA, pH 8.3, VAPOR DIFFUSION, HANGING DROP, temperature 291.0K
|
Resolution 1.90 Å R-free 0.305 |
| 1R8P HPV-16 E2C solution structure Deposited 2003-10-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
286–365（80 aa）
Fragment：DNA binding domain
Chain B
286–365（80 aa）
Fragment：DNA binding domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5；303 K；Ionic strength (raw mmCIF value) 50mM Phosphate；Pressure ambient
NMR sample composition
1.8mM 15N-labeled HPV-16 E2C, 50mM Sodium Phosphate, 5mM DTT | 95% H2O/5% D2O
NMR sample composition
0.9mM 13C,15N-labeled HPV-16 E2C, 50mM Sodium Phosphate, 5mM DTT | 95% H2O/5% D2O
NMR sample composition
0.2mM 15N-labeled HPV-16 E2C, 50mM Sodium Phosphate, 5mM DTT | 6% polyacrylamide gel
|
Resolution not provided |
| 1ZZF The DNA-bound solution structure of HPV-16 E2 DNA-binding domain Deposited 2005-06-14 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
286–365（80 aa）
Fragment：DNA-binding domain
Chain B
286–365（80 aa）
Fragment：DNA-binding domain
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5.6；318 K；Ionic strength (raw mmCIF value) 250 mM NaCl；Pressure ambient
NMR sample composition
DNA-E2C complex (15N) 0.6mM, 25mM Acetate+ 10mM Phosphate, pH 5.6, NaCl 250mM, DTT 5mM | 95% H20, 5% D2O
NMR sample composition
DNA-E2C complex (15N, 13C) 0.6mM, 25mM Acetate+ 10mM Phosphate, pH 5.6, NaCl 250mM, DTT 5mM | 95% H20, 5% D2O
NMR sample composition
DNA-E2C complex (15N) 0.2mM, 25mM Acetate+ 10mM Phosphate, pH 5.6, NaCl 250mM, DTT 5mM, Philamentosus phage 17mg/ml | 95% H20, 5% D2O
|
Resolution not provided |
| 2NNU Crystal Structure of the Papillomavirus DNA Tethering Complex E2:Brd4 Deposited 2006-10-24 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–201（201 aa）
Fragment：Activation Domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；100mM citrate, 1.8-2.0M Na-acetate, 10mM DTT, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.59 Å R-free 0.233 |
| 2NNU Crystal Structure of the Papillomavirus DNA Tethering Complex E2:Brd4 Deposited 2006-10-24 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
1–201（201 aa）
Fragment：Activation Domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；100mM citrate, 1.8-2.0M Na-acetate, 10mM DTT, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.59 Å R-free 0.233 |
| 2Q79 Crystal Structure of single chain E2C from HPV16 with a 12aa linker for monomerization. Deposited 2007-06-06 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
285–365（81 aa）
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.21；298 K；80 mM sodium citrate, 1.53 M (NH4)2SO4, 150 mM sodium and potassium tartrate, pH 5.21, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.80 Å R-free 0.241 |
| 3MI7 An Enhanced Repressor of Human Papillomavirus E2 Protein Deposited 2010-04-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain X
283–365（83 aa）
Fragment：UNP residues 283-365
|
Mutation：H290E, C309S | EDO 1,2-ETHANEDIOL × 12 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.8；277 K；100 mM sodium citrate, 100 mM ammonium acetate, 10% PEG 4000, pH 6.8, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.281 |