← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P04228 New Search
15PDB entries
23Biological assembly
26chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1ES0 CRYSTAL STRUCTURE OF THE MURINE CLASS II ALLELE I-A(G7) COMPLEXED WITH THE GLUTAMIC ACID DECARBOXYLASE (GAD65) PEPTIDE 207-220 Deposited 2000-04-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–205（182 aa） Fragment：ALPHA CHAIN
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；16-18% PEG 4000, 0.2 M LICL (PH 6.6), 1% MPD, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.60 Å R-free 0.258
1F3J HISTOCOMPATIBILITY ANTIGEN I-AG7 Deposited 2000-06-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 27–208（182 aa） Fragment：A-D ALPHA CHAIN
Chain D 27–208（182 aa） Fragment：A-D ALPHA CHAIN
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.4；pH 4.4
Resolution 3.10 Å R-free 0.299
1IAO CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339 Deposited 1998-03-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 24–209（186 aa）
Chain B 28–216（189 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；32% PEG 600, 0.1 IMIDAZOLE MALATE, PH 5.5
Resolution 2.60 Å R-free 0.320
1IAO CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339 Deposited 1998-03-13 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–209（186 aa）
Chain B 28–216（189 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；32% PEG 600, 0.1 IMIDAZOLE MALATE, PH 5.5
Resolution 2.60 Å R-free 0.320
2IAD CLASS II MHC I-AD IN COMPLEX WITH AN INFLUENZA HEMAGGLUTININ PEPTIDE 126-138 Deposited 1998-03-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 24–209（186 aa） Fragment：RESIDUES 126P - 138P OF CHAIN B ARE COVALENTLY LINKED INFLUENZA HEMAGGLUTININ PEPTIDE
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；19% PEG 8000 0.2 M TRIS, PH 7.4
Resolution 2.40 Å R-free 0.308
2IAD CLASS II MHC I-AD IN COMPLEX WITH AN INFLUENZA HEMAGGLUTININ PEPTIDE 126-138 Deposited 1998-03-13 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–209（186 aa） Fragment：RESIDUES 126P - 138P OF CHAIN B ARE COVALENTLY LINKED INFLUENZA HEMAGGLUTININ PEPTIDE
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；19% PEG 8000 0.2 M TRIS, PH 7.4
Resolution 2.40 Å R-free 0.308
3CUP Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235 Deposited 2008-04-16 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–205（182 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；295 K；0.1M Hepes pH 7.5, 28% PEG 8000, 2% Jeffamine 900, VAPOR DIFFUSION, SITTING DROP, temperature 295K, pH 7.50
Resolution 3.09 Å R-free 0.286
3MBE TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27) Deposited 2010-03-25 Assembly 1 Other combination Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 24–205（182 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；20% PEG4000, 0.2M K formate, 0.1M Na Cacodylate., pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 2.89 Å R-free 0.281
3MBE TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27) Deposited 2010-03-25 Assembly 2 Other combination Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain E 24–205（182 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；20% PEG4000, 0.2M K formate, 0.1M Na Cacodylate., pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 2.89 Å R-free 0.281
5DMK Crystal Structure of IAg7 in complex with RLGL-WE14 Deposited 2015-09-08 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 26–198（173 aa）
Not recorded FLC CITRATE ANION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；1M Ammonium Citrate
Resolution 2.45 Å R-free 0.260
5DMK Crystal Structure of IAg7 in complex with RLGL-WE14 Deposited 2015-09-08 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 26–198（173 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；1M Ammonium Citrate
Resolution 2.45 Å R-free 0.260
5DMK Crystal Structure of IAg7 in complex with RLGL-WE14 Deposited 2015-09-08 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 26–198（173 aa）
Not recorded FLC CITRATE ANION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；1M Ammonium Citrate
Resolution 2.45 Å R-free 0.260
5DMK Crystal Structure of IAg7 in complex with RLGL-WE14 Deposited 2015-09-08 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 26–198（173 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；1M Ammonium Citrate
Resolution 2.45 Å R-free 0.260
6BLQ Crystal Structure of IAg7 in complex with insulin mimotope p8E9E Deposited 2017-11-11 Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 24–208（185 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 IPA ISOPROPYL ALCOHOL × 4 EDO 1,2-ETHANEDIOL × 7 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；20% PEG3350, 100mM sodium citrate at pH5.0, 5% isopropanol
Resolution 1.80 Å R-free 0.203
6BLR Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS Deposited 2017-11-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 26–208（183 aa）
Mutation：N64C EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；278 K；15% PEG4000, 10mM sodium citrate at pH5.0, 100 mM MgCl2
Resolution 1.96 Å R-free 0.228
6BLX Crystal structure of IAg7 in complex with insulin mimotope p8G9E Deposited 2017-11-11 Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 26–208（183 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 EDO 1,2-ETHANEDIOL × 4 FMT FORMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；278 K；18% PEG20000, 100mM sodium citrate at pH5.0
Resolution 2.32 Å R-free 0.220
6DFS mouse TCR I.29 in complex with IAg7-p8E9E6ss Deposited 2018-05-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 26–208（183 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；12% PEG 20000, 100mM bicine pH9.0, 20% ethylene glycol
Resolution 3.10 Å R-free 0.285
6DFW TCR 8F10 in complex with IAg7-p8G9E Deposited 2018-05-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 26–208（183 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；11% PEG 3350, 100mM formate pH7.0
Resolution 3.20 Å R-free 0.297
6DFW TCR 8F10 in complex with IAg7-p8G9E Deposited 2018-05-15 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 26–208（183 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；11% PEG 3350, 100mM formate pH7.0
Resolution 3.20 Å R-free 0.297
7QHP Structure of I-Ag7 with a bound hybrid insulin peptide Deposited 2021-12-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 24–218（195 aa）
Mutation：I91C GOL GLYCEROL × 2 SO4 SULFATE ION × 1 NA SODIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.17 M ammonium sulfate, 25% w/v PEG 4000, 15% glycerol
Resolution 1.82 Å R-free 0.219
7RDV TFH TCR bound to MHC Class II IAd presenting aggrecan epitope Deposited 2021-07-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 28–205（178 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293.15 K；0.1M Sodium Cacodylate pH6.0 15% w/v PEG4000
Resolution 2.90 Å R-free 0.265
7Z50 Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7. Deposited 2022-03-06 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 24–218（195 aa）
Mutation：I91C NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 EDO 1,2-ETHANEDIOL × 3 NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；0.1 M MgCl2, 0.1 M Na HEPES pH 7.0, 15% w/v PEG 4000
Resolution 2.65 Å R-free 0.261
7Z50 Structure of the highly diabetogenic 4.1-T cell receptor targeting a hybrid insulin peptide bound to I-Ag7. Deposited 2022-03-06 Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain C 24–218（195 aa）
Mutation：I91C NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 EDO 1,2-ETHANEDIOL × 3 NA SODIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；0.1 M MgCl2, 0.1 M Na HEPES pH 7.0, 15% w/v PEG 4000
Resolution 2.65 Å R-free 0.261

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.