Current Protein Identity：P04839
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3A1F The crystal structure of NADPH binding domain of gp91(phox) Deposited 2009-04-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
385–570（186 aa）
Fragment：UNP residues 385-570
|
Not recorded | NI NICKEL (II) ION × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.6；293 K；12% PEG 3350, 0.1M sodium acetate pH 5.6, 0.4M NiCl2, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.277 |
| 7U8G Cryo-EM structure of the core human NADPH oxidase NOX2 Deposited 2022-03-08 | Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–570（569 aa）
Fragment：N-terminal 2x streptag followed by EGFP and TEV + thrombin cleavage sites.
|
Not recorded | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8；0.03% DDM, 150 mM NaCl, 20 mM Tris
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8GZ3 Structure of human phagocyte NADPH oxidase in the resting state Deposited 2022-09-24 | Assembly 1 Other combination Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain B
1–570（570 aa）
|
Not recorded | FAD FLAVIN-ADENINE DINUCLEOTIDE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 LBN 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 8KEI Cryo-EM structure of NADPH oxidase 2 in complex with p22phox and EROS Deposited 2023-08-11 | Assembly 1 Other combination Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain B
6–570（565 aa）
|
Not recorded | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 LBN 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.56 Å |
| 8WEJ Structure of human phagocyte NADPH oxidase in the activated state Deposited 2023-09-18 | Assembly 1 Other combination Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain B
1–570（570 aa）
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 2 NDP NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 FDA DIHYDROFLAVINE-ADENINE DINUCLEOTIDE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.79 Å |
| 8X2L Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH Deposited 2023-11-09 | Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
1–570（570 aa）
|
Not recorded | FAD FLAVIN-ADENINE DINUCLEOTIDE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.99 Å |