Current Protein Identity：P07355
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1W7B Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein. Deposited 2004-09-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
0–338（339 aa）
|
Mutation：YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；2.5 M NACL 0.1 M ACETATE PH 4.5 0.2 M LI2SO4
|
Resolution 1.52 Å R-free 0.240 |
| 1XJL Structure of human annexin A2 in the presence of calcium ions Deposited 2004-09-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
20–338（319 aa）
Chain B
20–338（319 aa）
|
Mutation：A66E Mutation：A66E | CA CALCIUM ION × 14 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；PEG8000, calcium acetate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.59 Å R-free 0.264 |
| 2HYU Human Annexin A2 with heparin tetrasaccharide bound Deposited 2006-08-07 | Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
31–338（308 aa）
|
Not recorded | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
hanging drop；pH 5；290 K；1,6 hexanediol, pH 5.0, hanging drop, temperature 290K
|
Resolution 1.86 Å R-free 0.233 |
| 2HYV Human Annexin A2 with heparin hexasaccharide bound Deposited 2006-08-07 | Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
31–338（308 aa）
|
Not recorded | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
hanging drop；pH 5；290 K；1,6 hexanediol, pH 5.0, hanging drop, temperature 290K
|
Resolution 1.42 Å R-free 0.223 |
| 2HYW Human Annexin A2 with Calcium bound Deposited 2006-08-07 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
31–338（308 aa）
|
Not recorded | CA CALCIUM ION × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
hanging drop；pH 8.5；290 K；PEG 8000, pH 8.5, hanging drop, temperature 290K
|
Resolution 2.10 Å R-free 0.257 |
| 2HYW Human Annexin A2 with Calcium bound Deposited 2006-08-07 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
31–338（308 aa）
|
Not recorded | CA CALCIUM ION × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
hanging drop；pH 8.5；290 K；PEG 8000, pH 8.5, hanging drop, temperature 290K
|
Resolution 2.10 Å R-free 0.257 |
| 4DRW Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide Deposited 2012-02-17 | Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain A
2–16（15 aa）
Fragment：UNP P60903 residues 1-93 and UNP P07355 residues 2-16
Chain B
2–16（15 aa）
Fragment：UNP P60903 residues 1-93 and UNP P07355 residues 2-16
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；100mM sodium chloride, 200mM magnesium chloride, 50mM sodium cacodylate, 20% PEG 1000, 0.15mM CYMAL-7, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.50 Å R-free 0.327 |
| 4DRW Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide Deposited 2012-02-17 | Assembly 2 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
2–16（15 aa）
Fragment：UNP P60903 residues 1-93 and UNP P07355 residues 2-16
Chain D
2–16（15 aa）
Fragment：UNP P60903 residues 1-93 and UNP P07355 residues 2-16
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；100mM sodium chloride, 200mM magnesium chloride, 50mM sodium cacodylate, 20% PEG 1000, 0.15mM CYMAL-7, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.50 Å R-free 0.327 |
| 4FTG The crystal structure of an AHNAK peptide in complex with the S100A10/AnxA2 heterotetramer Deposited 2012-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain C
2–16（15 aa）
Fragment：Annexin A2 N-terminal peptide (UNP residues 2-16)
Chain D
2–16（15 aa）
Fragment：Annexin A2 N-terminal peptide (UNP residues 2-16)
|
Mutation：C9S Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：C9S Non-standard monomer：Yes (specific site not provided by mmCIF) | IPA ISOPROPYL ALCOHOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；290 K；20% PEG 8000 (w/v), 0.1 M Tris pH 8.5, 10% 2-propanol, VAPOR DIFFUSION, HANGING DROP, temperature 290K
|
Resolution 2.51 Å R-free 0.251 |
| 4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 | Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–16（15 aa）
Chain B
2–16（15 aa）
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 3.00 Å R-free 0.263 |
| 4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–16（15 aa）
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 3.00 Å R-free 0.263 |
| 4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 | Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
2–16（15 aa）
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 3.00 Å R-free 0.263 |
| 4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 | Assembly 4 Insufficient information Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count |
Chain A
2–16（15 aa）
Chain B
2–16（15 aa）
|
Not recorded | SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 3.00 Å R-free 0.263 |
| 5LPU Crystal structure of Annexin A2 complexed with S100A4 Deposited 2016-08-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–339（338 aa）
Chain B
2–339（338 aa）
|
Mutation：A66E Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：A66E Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 14 GOL GLYCEROL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1M Bis Tris pH 6.5, 0.2M ammonium acetate 4% PEG4000 and 1,5% glycerol
|
Resolution 2.10 Å R-free 0.207 |
| 5LPX Crystal structure of PKC phosphorylation-mimicking mutant (S26E) Annexin A2 Deposited 2016-08-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–339（338 aa）
|
Mutation：S26E, A66E Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 5 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1 M Bis-Tris pH 6, 0.2 M ammonium acetate, 5% PEG 3350
|
Resolution 1.90 Å R-free 0.182 |
| 5LQ0 Crystal structure of Tyr24 phosphorylated Annexin A2 at 2.9 A resolution Deposited 2016-08-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–339（338 aa）
|
Mutation：A66E Y24(PTR) Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1 M MES pH 6, 0.1 M magnesium chloride, 4% PEG6000
|
Resolution 2.90 Å R-free 0.260 |
| 5LQ0 Crystal structure of Tyr24 phosphorylated Annexin A2 at 2.9 A resolution Deposited 2016-08-15 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–339（338 aa）
|
Mutation：A66E Y24(PTR) Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1 M MES pH 6, 0.1 M magnesium chloride, 4% PEG6000
|
Resolution 2.90 Å R-free 0.260 |
| 5LQ2 Crystal structure of Tyr24 phosphorylated Annexin A2 at 3.4 A resolution Deposited 2016-08-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–339（338 aa）
|
Mutation：A66E Y24(PTR) Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1 M Tris pH 8.5, 10% ethanol
|
Resolution 3.40 Å R-free 0.234 |
| 5LQ2 Crystal structure of Tyr24 phosphorylated Annexin A2 at 3.4 A resolution Deposited 2016-08-15 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–339（338 aa）
|
Mutation：A66E Y24(PTR) Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；0.1 M Tris pH 8.5, 10% ethanol
|
Resolution 3.40 Å R-free 0.234 |
| 5N7D MAGI-1 complexed with a RSK1 peptide Deposited 2017-02-20 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 3 CA CALCIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5；296 K；8% PEG 400, 100 mM acetate buffer
|
Resolution 2.30 Å R-free 0.227 |
| 5N7D MAGI-1 complexed with a RSK1 peptide Deposited 2017-02-20 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 2 CA CALCIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5；296 K；8% PEG 400, 100 mM acetate buffer
|
Resolution 2.30 Å R-free 0.227 |
| 5N7F MAGI-1 complexed with a pRSK1 peptide Deposited 2017-02-20 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 3 CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；296 K；14% PEG 8000, 200 mM MgCl2, 100 mM TRIS
|
Resolution 2.30 Å R-free 0.240 |
| 5N7F MAGI-1 complexed with a pRSK1 peptide Deposited 2017-02-20 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 3 CA CALCIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；296 K；14% PEG 8000, 200 mM MgCl2, 100 mM TRIS
|
Resolution 2.30 Å R-free 0.240 |
| 5N7G MAGI-1 complexed with a synthetic pRSK1 peptide Deposited 2017-02-20 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | GOL GLYCEROL × 3 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；296 K；14% PEG 8000, 200 mM MgCl2, 100 mM TRIS
|
Resolution 2.95 Å R-free 0.264 |
| 5N7G MAGI-1 complexed with a synthetic pRSK1 peptide Deposited 2017-02-20 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | GOL GLYCEROL × 2 CA CALCIUM ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；296 K；14% PEG 8000, 200 mM MgCl2, 100 mM TRIS
|
Resolution 2.95 Å R-free 0.264 |
| 6T58 Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone Deposited 2019-10-15 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
29–339（311 aa）
|
Mutation：A280E,A280E,A280E,A280E | GOL GLYCEROL × 2 CA CALCIUM ION × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.12 M Alcohols
0.1 M Sodium HEPES; MOPS (acid) pH7.5
20% v/v Ethylene glycol; 10 % w/v PEG 8000
Morpheus D6
|
Resolution 3.10 Å R-free 0.272 |
| 6T58 Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone Deposited 2019-10-15 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
29–339（311 aa）
|
Mutation：A280E,A280E,A280E,A280E | GOL GLYCEROL × 2 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.12 M Alcohols
0.1 M Sodium HEPES; MOPS (acid) pH7.5
20% v/v Ethylene glycol; 10 % w/v PEG 8000
Morpheus D6
|
Resolution 3.10 Å R-free 0.272 |
| 6TWQ MAGI1_2 complexed with a 16E6 peptide Deposited 2020-01-13 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | CIT CITRIC ACID × 2 GOL GLYCEROL × 1 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100 mM Na-citrate (pH 5.5), 100 mM Na-citrate
|
Resolution 2.65 Å R-free 0.262 |
| 6TWQ MAGI1_2 complexed with a 16E6 peptide Deposited 2020-01-13 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CIT CITRIC ACID × 1 GOL GLYCEROL × 1 CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100 mM Na-citrate (pH 5.5), 100 mM Na-citrate
|
Resolution 2.65 Å R-free 0.262 |
| 6TWU MAGI1_2 complexed with a phosphomimetic 16E6 peptide Deposited 2020-01-13 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 2 CIT CITRIC ACID × 1 CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (pH5.5), 100mM Na-citrate
|
Resolution 2.40 Å R-free 0.255 |
| 6TWU MAGI1_2 complexed with a phosphomimetic 16E6 peptide Deposited 2020-01-13 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 1 CIT CITRIC ACID × 2 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (pH5.5), 100mM Na-citrate
|
Resolution 2.40 Å R-free 0.255 |
| 6TWX MAGI1_2 complexed with a phosphorylated 16E6 peptide Deposited 2020-01-13 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | GOL GLYCEROL × 1 CIT CITRIC ACID × 1 CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (5.5), 100mM Na-citrate
|
Resolution 2.30 Å R-free 0.259 |
| 6TWX MAGI1_2 complexed with a phosphorylated 16E6 peptide Deposited 2020-01-13 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | GOL GLYCEROL × 1 CIT CITRIC ACID × 2 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (5.5), 100mM Na-citrate
|
Resolution 2.30 Å R-free 0.259 |
| 6TWY MAGI1_2 complexed with a phosphomimetic RSK1 peptide Deposited 2020-01-13 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 2 CIT CITRIC ACID × 1 CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (pH 5.5), 100mM Na-citrate
|
Resolution 2.30 Å R-free 0.250 |
| 6TWY MAGI1_2 complexed with a phosphomimetic RSK1 peptide Deposited 2020-01-13 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
40–357（318 aa）
|
Not recorded | GOL GLYCEROL × 1 CIT CITRIC ACID × 2 CA CALCIUM ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；296 K；22% PEG3000, 100mM Na-citrate (pH 5.5), 100mM Na-citrate
|
Resolution 2.30 Å R-free 0.250 |
| 7DTO Human Annexin A2 with C132-C261 intramolecular disulfide bond Deposited 2021-01-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
31–339（309 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6.5；289 K；13% PEG 550 MME, 0.1 M Bis-Tris pH 6.5, 50 mM NaCl
|
Resolution 2.80 Å R-free 0.223 |
| 7EQ7 Co-Crystal Structure Analysis of Annexin A2 and 5alpha-EAL Deposited 2021-04-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–339（339 aa）
|
Not recorded | CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 7；293 K；100 mM Tris, 20% PEG3350, 0.2 M sodium acetate
|
Resolution 2.11 Å R-free 0.251 |
| 7NMI Transactivation domain of p53 in complex with S100P, using annexin A2 as crystallization chaperone Deposited 2021-02-23 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
29–339（311 aa）
|
Mutation：A238E | GOL GLYCEROL × 1 CA CALCIUM ION × 9 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；Morpheus screen (MD) H6
0.1 M Amino acids, 0.1 M Buffer System 2, pH 7.5, 30 % v/v Precipitant Mix 2
|
Resolution 2.10 Å R-free 0.228 |
| 7P70 The PDZ-domain of SNTB1 complexed with the PDZ-binding motif of HPV35-E6 Deposited 2021-07-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；20% polyethylene glycol 3350, 200 mM sodium malonate buffered at pH 7.0
|
Resolution 2.00 Å R-free 0.209 |
| 7P71 The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6 Deposited 2021-07-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 3 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；20-25% polyethylene glycol 3000, 100 mM sodium citrate buffered at pH 5.5 and 100 mM trisodium-citrate
|
Resolution 2.60 Å R-free 0.281 |
| 7P71 The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6 Deposited 2021-07-19 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；20-25% polyethylene glycol 3000, 100 mM sodium citrate buffered at pH 5.5 and 100 mM trisodium-citrate
|
Resolution 2.60 Å R-free 0.281 |
| 7P72 The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E Deposited 2021-07-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；10% polyethylene glycol 8000, 100 mM imidazole buffered at pH 8.0
|
Resolution 2.15 Å R-free 0.240 |
| 7P73 The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 Deposited 2021-07-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
23–339（317 aa）
|
Not recorded | CA CALCIUM ION × 7 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；120mM Monosaccharides, 100mM Buffer System 3 pH 8.5, 50 % Precipitant Mix 2 (F10 Morpheus)
|
Resolution 1.85 Å R-free 0.192 |
| 7P74 The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1 Deposited 2021-07-19 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；100mM ammonium sulfate, 100mM sodium formate, 25% PEG smear broad
|
Resolution 1.90 Å R-free 0.211 |
| 7PC3 The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1 Deposited 2021-08-03 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 4 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M Lithium sulfate, 0.1 M bis-Tris pH 5.5, 25% w/v PEG 3350
|
Resolution 1.95 Å R-free 0.201 |
| 7PC4 The PDZ domain of SNTB1 complexed with the PDZ-binding motif of HTLV1-TAX1 Deposited 2021-08-03 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M HEPES pH 7.5, 10% w/v PEG 8000, 8% v/v Ethylene glycol
|
Resolution 2.30 Å R-free 0.260 |
| 7PC5 The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4 Deposited 2021-08-03 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2M ammonium sulfate, 15% PEG 4000, 0.1M TRIS pH8.5
|
Resolution 1.70 Å R-free 0.188 |
| 7PC7 The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN Deposited 2021-08-03 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 6 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M Tris 8.5, 22 % v/v PEG Smear Broad
|
Resolution 2.10 Å R-free 0.218 |
| 7PC7 The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN Deposited 2021-08-03 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 6 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M Tris 8.5, 22 % v/v PEG Smear Broad
|
Resolution 2.10 Å R-free 0.218 |
| 7PC8 The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 Deposited 2021-08-03 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.15 M Lithium sulfate, 0.05 M Magnesium chloride hexahydrate ,0.1 M HEPES 7.8, 20 % v/v PEG Smear High
|
Resolution 2.50 Å R-free 0.232 |
| 7PC8 The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 Deposited 2021-08-03 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.15 M Lithium sulfate, 0.05 M Magnesium chloride hexahydrate ,0.1 M HEPES 7.8, 20 % v/v PEG Smear High
|
Resolution 2.50 Å R-free 0.232 |
| 7PC9 The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 Deposited 2021-08-03 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M HEPES pH 7.5, 10% w/v PEG 8000, 8% v/v Ethylene glycol
|
Resolution 2.40 Å R-free 0.243 |
| 7PC9 The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 Deposited 2021-08-03 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M HEPES pH 7.5, 10% w/v PEG 8000, 8% v/v Ethylene glycol
|
Resolution 2.40 Å R-free 0.243 |
| 7PCB The PDZ domain of SNX27 fused with ANXA2 Deposited 2021-08-03 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M Potassium thiocyanate 0.1 M Sodium bromide 0.1 M MES 6.5 12 % v/v PEG Smear High
|
Resolution 2.00 Å R-free 0.205 |
| 7QQL The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1 Deposited 2022-01-10 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.1 M Succinic acid pH 7.0 15% w/v PEG 3350
|
Resolution 2.44 Å R-free 0.230 |
| 7QQL The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1 Deposited 2022-01-10 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.1 M Succinic acid pH 7.0 15% w/v PEG 3350
|
Resolution 2.44 Å R-free 0.230 |
| 7QQL The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1 Deposited 2022-01-10 | Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
29–339（311 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.1 M Succinic acid pH 7.0 15% w/v PEG 3350
|
Resolution 2.44 Å R-free 0.230 |
| 7QQM The PDZ domain of LRRC7 fused with ANXA2 Deposited 2022-01-10 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
23–339（317 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.1 M Potassium thiocyanate 0.1 M Sodium bromide 0.1 M MES 6.5 12 % v/v PEG Smear High
|
Resolution 1.60 Å R-free 0.198 |
| 7QQN The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 Deposited 2022-01-10 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.15 M Lithium sulfate 0.05 M Magnesium chloride hexahydrate 0.1 M HEPES 7.8 20 % v/v PEG Smear High
|
Resolution 2.45 Å R-free 0.263 |
| 7QQN The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 Deposited 2022-01-10 | Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 5 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；0.15 M Lithium sulfate 0.05 M Magnesium chloride hexahydrate 0.1 M HEPES 7.8 20 % v/v PEG Smear High
|
Resolution 2.45 Å R-free 0.263 |
| 7ZVN Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution Deposited 2022-05-16 | Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers |
Chain A
34–339（306 aa）
|
Not recorded | GOL GLYCEROL × 8 CA CALCIUM ION × 7 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.3；290 K；4% w/v PEG 4000, 14% v/v glycerol, 0.03 M MgCl2/CaCl2, 0.1 M bicine/Trizma base pH 8.3
|
Resolution 1.87 Å R-free 0.198 |
| 7ZVX Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution Deposited 2022-05-17 | Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: dimeric（2） Consistent with all polymers |
Chain A
34–339（306 aa）
|
Not recorded | CA CALCIUM ION × 5 EDO 1,2-ETHANEDIOL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.1；290 K；12% w/v PEG 8000, 24% v/v ethylene glycol, 0.02 M sodium formate/ammonium acetate/trisodium citrate/sodium potassium L-tartrate/sodium oxamate, 0.1 M MES/imidazole pH 6.1
|
Resolution 2.40 Å R-free 0.242 |
| 7ZVX Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution Deposited 2022-05-17 | Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: dimeric（2） Consistent with all polymers |
Chain B
34–339（306 aa）
|
Not recorded | CA CALCIUM ION × 6 EDO 1,2-ETHANEDIOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.1；290 K；12% w/v PEG 8000, 24% v/v ethylene glycol, 0.02 M sodium formate/ammonium acetate/trisodium citrate/sodium potassium L-tartrate/sodium oxamate, 0.1 M MES/imidazole pH 6.1
|
Resolution 2.40 Å R-free 0.242 |
| 8AEL SYNJ2BP complex with a synthetic Vangl2 peptide (3mer). Deposited 2022-07-13 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
22–339（318 aa）
|
Not recorded | CA CALCIUM ION × 4 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；0.1 M Ammonium Sulfate, 0.1 M Sodium formate, 0.1 M HEPES 7.0, 25% v/v PEG Smear Broad
|
Resolution 2.20 Å R-free 0.264 |