Current Protein Identity：P07358
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3OJY Crystal Structure of Human Complement Component C8 Deposited 2010-08-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain B
55–591（537 aa）
Fragment：unp residues 55-591
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 2 BMA beta-D-mannopyranose × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；281 K；14-16% PEG 4K, 100mM TAPS pH 9.0, 400mM NaCl, 10mM SrCl2, VAPOR DIFFUSION, HANGING DROP, temperature 281K
|
Resolution 2.51 Å R-free 0.337 |
| 6H03 OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX Deposited 2018-07-06 | Assembly 1 Other combination Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count |
Chain C
55–591（537 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 37 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.60 Å |
| 6H04 Closed conformation of the Membrane Attack Complex Deposited 2018-07-06 | Assembly 1 Other combination Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count |
Chain C
55–591（537 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 38 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.60 Å |
| 7NYC cryoEM structure of 3C9-sMAC Deposited 2021-03-22 | Assembly 1 Other combination Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count |
Chain D
55–591（537 aa）
|
Not recorded | MAN alpha-D-mannopyranose × 7 CA CALCIUM ION × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 FUC alpha-L-fucopyranose × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.54 Å |
| 7NYD cryoEM structure of 2C9-sMAC Deposited 2021-03-22 | Assembly 1 Other combination Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain D
55–591（537 aa）
|
Not recorded | MAN alpha-D-mannopyranose × 6 CA CALCIUM ION × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 FUC alpha-L-fucopyranose × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.27 Å |
| 8B0F CryoEM structure of C5b8-CD59 Deposited 2022-09-07 | Assembly 1 Other combination Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain D
1–591（591 aa）
|
Not recorded | CA CALCIUM ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å |
| 8B0G 2C9, C5b9-CD59 structure Deposited 2022-09-07 | Assembly 1 Other combination Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count |
Chain D
1–591（591 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4；20 mM HEPES pH 7.4, 120 mM NaCl
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 8B0H 2C9, C5b9-CD59 cryoEM structure Deposited 2022-09-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count |
Chain D
1–591（591 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4；20 mM HEPES pH 7.4, 120 mM NaCl
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |