Current Protein Identity:P13498
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1WLP Solution Structure Of The P22Phox-P47Phox Complex Deposited 2004-06-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
148–167(20 aa)
Fragment:Alpha Polypeptide (1-25)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR | mmCIF provides none of the parsed conditions | Resolution not provided |
| 7U8G Cryo-EM structure of the core human NADPH oxidase NOX2 Deposited 2022-03-08 | Assembly 1 Insufficient information Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain B
1–195(195 aa)
|
Not recorded | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8;0.03% DDM, 150 mM NaCl, 20 mM Tris
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 7YXW Structure of the p22phox A200G mutant in complex with p47phox peptide Deposited 2022-02-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
151–168(18 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;277 K;0.1 M HEPES pH 7.5, 1.2 M sodium citrate tribasic dihydrate, 1:1 protein:precipitant ratio
|
Resolution 2.50 Å R-free 0.269 |
| 8GZ3 Structure of human phagocyte NADPH oxidase in the resting state Deposited 2022-09-24 | Assembly 1 Other combination Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–195(195 aa)
|
Not recorded | FAD FLAVIN-ADENINE DINUCLEOTIDE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 LBN 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 8KEI Cryo-EM structure of NADPH oxidase 2 in complex with p22phox and EROS Deposited 2023-08-11 | Assembly 1 Other combination Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
3–135(133 aa)
|
Not recorded | POV (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 LBN 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.56 Å |
| 8WEJ Structure of human phagocyte NADPH oxidase in the activated state Deposited 2023-09-18 | Assembly 1 Other combination Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain A
1–195(195 aa)
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 2 NDP NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 FDA DIHYDROFLAVINE-ADENINE DINUCLEOTIDE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.79 Å |
| 8X2L Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH Deposited 2023-11-09 | Assembly 1 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–195(195 aa)
|
Not recorded | FAD FLAVIN-ADENINE DINUCLEOTIDE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.99 Å |