当前蛋白身份：P15289
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 1AUK HUMAN ARYLSULFATASE A 提交 1997-08-29 | Assembly 1 其他组合 同源多聚体；蛋白 × 8 PDB 声明：octameric（8） 与蛋白数一致 |
链 A
19–507（489 aa）
|
非标准单体：是（mmCIF未提供具体位点） | MG MAGNESIUM ION × 8 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5.4；291 K；PROTEIN WAS CRYSTALLIZED BY VAPOR DIFFUSION IN HANGING DROPS AT 291 K. SOLUTION CONTAINING 10MG/ML PROTEIN, 10 MM TRIS/HCL (PH 7.4) AND 150 MM NACL WAS MIXED WITH SAME VOLUME OF RESERVOIR SOLUTION, CONTAINING 100 MM NA-ACETATE (PH 5.0 - 5.4) AND 10 - 13 % PEG 6000, vapor diffusion - hanging drop
|
分辨率 2.10 Å R-free 0.273 |
| 1E1Z Crystal structure of an Arylsulfatase A mutant C69S 提交 2000-05-12 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
19–507（489 aa）
|
突变：C69S | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5.4；291 K；PROTEIN WAS CRYSTALLIZED BY VAPOR DIFFUSION IN HANGING DROPS AT 291 K. SOLUTION CONTAINING 10MG/ML PROTEIN, 10 MM TRIS/HCL (PH 7.4) AND 150 MM NACL WAS MIXED WITH SAME VOLUME OF RESERVOIR SOLUTION, CONTAINING 100 MM NA-ACETATE (PH 5.0 - 5.4) AND 10 - 13 % PEG 6000
|
分辨率 2.40 Å R-free 0.243 |
| 1E2S Crystal structure of an Arylsulfatase A mutant C69A 提交 2000-05-24 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
19–507（489 aa）
|
突变：C69A | MG MAGNESIUM ION × 2 CSN N,4-DIHYDROXY-N-OXO-3-(SULFOOXY)BENZENAMINIUM × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5.4；291 K；PROTEIN WAS CRYSTALLIZED BY VAPOR DIFFUSION IN HANGING DROPS AT 291 K. SOLUTION CONTAINING 10MG/ML PROTEIN, 10 MM TRIS/HCL (PH 7.4) AND 150 MM NACL WAS MIXED WITH SAME VOLUME OF RESERVOIR SOLUTION, CONTAINING 100 MM NA-ACETATE (PH 5.0 - 5.4) AND 10 - 13 % PEG 6000
|
分辨率 2.35 Å R-free 0.236 |
| 1E33 Crystal structure of an Arylsulfatase A mutant P426L 提交 2000-06-06 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
19–507（489 aa）
|
突变：P426L 非标准单体：是（mmCIF未提供具体位点） | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5.4；291 K；PROTEIN WAS CRYSTALLIZED BY VAPOR DIFFUSION IN HANGING DROPS AT 291 K. SOLUTION CONTAINING 10MG/ML PROTEIN, 10 MM TRIS/HCL (PH 7.4) AND 150 MM NACL WAS MIXED WITH SAME VOLUME OF RESERVOIR SOLUTION, CONTAINING 100 MM NA-ACETATE (PH 5.0 - 5.4) AND 10 - 13 % PEG 6000
|
分辨率 2.50 Å R-free 0.250 |
| 1E3C Crystal structure of an Arylsulfatase A mutant C69S soaked in synthetic substrate 提交 2000-06-13 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
19–507（489 aa）
|
突变：C69S | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5.4；291 K；PROTEIN WAS CRYSTALLIZED BY VAPOR DIFFUSION IN HANGING DROPS AT 291 K. SOLUTION CONTAINING 10MG/ML PROTEIN, 10 MM TRIS/HCL (PH 7.4) AND 150 MM NACL WAS MIXED WITH SAME VOLUME OF RESERVOIR SOLUTION, CONTAINING 100 MM NA-ACETATE (PH 5.0 - 5.4) AND 10 - 13 % PEG 6000
|
分辨率 2.65 Å R-free 0.243 |
| 1N2K Crystal structure of a covalent intermediate of endogenous human arylsulfatase A 提交 2002-10-23 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 A
19–507（489 aa）
|
非标准单体：是（mmCIF未提供具体位点） | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.6；293 K；cacodylate, sodium fluoride, PEG8000, pH 6.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.75 Å R-free 0.239 |
| 1N2L Crystal structure of a covalent intermediate of endogenous human arylsulfatase A 提交 2002-10-23 | Assembly 1 其他组合 同源多聚体；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 A
19–507（489 aa）
|
非标准单体：是（mmCIF未提供具体位点） | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；cacodylate, sodium fluoride, PEG8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 3.20 Å R-free 0.223 |
| 2AIJ Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide CTPSR 提交 2005-07-29 | Assembly 1 其他组合 异源复合物；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
69–73（5 aa）
|
未记录 | CA CALCIUM ION × 2 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；PEG 4000, Calcium chloride, TRIS, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
分辨率 1.55 Å R-free 0.178 |
| 2AIK Formylglycine generating enzyme C336S mutant covalently bound to substrate peptide LCTPSRA 提交 2005-07-29 | Assembly 1 其他组合 异源复合物；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 P
68–74（7 aa）
|
未记录 | CA CALCIUM ION × 2 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；PEG 4000, Calcium chloride, TRIS, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
分辨率 1.73 Å R-free 0.174 |