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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P17948 New Search
11PDB entries
17Biological assembly
29chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1FLT VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR Deposited 1997-11-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 132–226（95 aa） Fragment：SECOND EXTRACELLULAR IGG LIKE DOMAIN, RESIDUES 129 - 229
Chain Y 132–226（95 aa） Fragment：SECOND EXTRACELLULAR IGG LIKE DOMAIN, RESIDUES 129 - 229
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.5
Resolution 1.70 Å R-free 0.261
1FLT VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR Deposited 1997-11-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain X 132–226（95 aa） Fragment：SECOND EXTRACELLULAR IGG LIKE DOMAIN, RESIDUES 129 - 229
Chain Y 132–226（95 aa） Fragment：SECOND EXTRACELLULAR IGG LIKE DOMAIN, RESIDUES 129 - 229
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；pH 8.5
Resolution 1.70 Å R-free 0.261
1QSV THE VEGF-BINDING DOMAIN OF FLT-1, 20 NMR STRUCTURES Deposited 1999-06-23 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–229（101 aa） Fragment：SECOND EXTRACELLULAR IMMUNOGLOBULIN-LIKE DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；300 K；Ionic strength (raw mmCIF value) 150mM；Pressure AMBIENT
NMR sample composition 1MM FLT-1(DOMAIN2) U-15N,13C; PHOSPHATE BUFFERED SALINE, PH 5.7; 50UM EDTA; 100UM NAN3; 50UM DSS
NMR sample composition 1MM FLT-1(DOMAIN2) U-15N; PHOSPHATE BUFFERED SALINE, PH 5.7; 50UM EDTA; 100UM NAN3; 50UM DSS
Resolution not provided
1QSZ THE VEGF-BINDING DOMAIN OF FLT-1 (MINIMIZED MEAN) Deposited 1999-06-24 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 129–229（101 aa） Fragment：SECOND EXTRACELLULAR IMMUNOGLOBULIN-LIKE DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；300 K；Ionic strength (raw mmCIF value) 150mM；Pressure AMBIENT
NMR sample composition 1MM FLT-1(DOMAIN2) U-15N,13C; PHOSPHATE BUFFERED SALINE, PH 5.7; 50UM EDTA; 100UM NAN3; 50UM DSS
NMR sample composition 1MM FLT-1(DOMAIN2) U-15N; PHOSPHATE BUFFERED SALINE, PH 5.7; 50UM EDTA; 100UM NAN3; 50UM DSS
NMR sample composition 1MM FLT-1(DOMAIN2) 15% 13C; PHOSPHATE BUFFERED SALINE, PH 5.7; 50UM EDTA; 100UM NAN3; 50UM DSS
Resolution not provided
1QTY VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR Deposited 1999-06-29 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 129–229（101 aa） Fragment：DOMAIN 2
Chain Y 129–229（101 aa） Fragment：DOMAIN 2
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 4000, AMMONIUMSULFATE, TRIS , pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.70 Å R-free 0.284
1QTY VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR Deposited 1999-06-29 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain T 129–229（101 aa） Fragment：DOMAIN 2
Chain U 129–229（101 aa） Fragment：DOMAIN 2
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 4000, AMMONIUMSULFATE, TRIS , pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.70 Å R-free 0.284
1QTY VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR Deposited 1999-06-29 Assembly 3 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain T 129–229（101 aa） Fragment：DOMAIN 2
Chain U 129–229（101 aa） Fragment：DOMAIN 2
Chain X 129–229（101 aa） Fragment：DOMAIN 2
Chain Y 129–229（101 aa） Fragment：DOMAIN 2
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 4000, AMMONIUMSULFATE, TRIS , pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.70 Å R-free 0.284
1RV6 Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 Deposited 2003-12-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 130–229（100 aa） Fragment：domain-2
Chain Y 130–229（100 aa） Fragment：domain-2
Not recorded B3P 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；pH 6.5
Resolution 2.45 Å R-free 0.260
2XAC Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity Deposited 2010-03-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 129–226（98 aa） Fragment：DOMAIN 2, RESIDUES 129-226
Chain X 129–226（98 aa） Fragment：DOMAIN 2, RESIDUES 129-226
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；14% PEG 4000, 0.1M SODIUM CITRATE, PH 5.6 AND 0.2M LICL
Resolution 2.71 Å R-free 0.364
3HNG Crystal structure of VEGFR1 in complex with N-(4-Chlorophenyl)-2-((pyridin-4-ylmethyl)amino)benzamide Deposited 2009-05-31 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 801–1158（358 aa） Fragment：KINASE DOMAIN, UNP residues 801-1158
Not recorded 8ST N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277 K；0.2M potassium formate, 20% PEG 3350, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.70 Å R-free 0.260
4CKV Crystal structure of VEGFR-1 domain 2 in presence of Zn Deposited 2014-01-09 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain X 132–225（94 aa） Fragment：DOMAIN-2, RESIDUES 132-225
Not recorded ZN ZINC ION × 2 EDO 1,2-ETHANEDIOL × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；291 K；VAPOR DIFFUSION METHOD, MOTHER LIQUOR:1MM VEGFR-1-D2,0.1%(W/V) DDM,4MM LAXAPHYCINE-A,5MM HEPES/NAOH PH 7.5. RESERVOIR:18% (W/V) PEG8000,100MM HEPES/NAOH PH 7.5, 18C
Resolution 2.06 Å R-free 0.205
4CL7 Crystal structure of VEGFR-1 domain 2 in presence of Cobalt Deposited 2014-01-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 132–225（94 aa） Fragment：DOMAIN-2, RESIDUES 132-225
Chain C 132–225（94 aa） Fragment：DOMAIN-2, RESIDUES 132-225
Not recorded CO COBALT (II) ION × 3 EDO 1,2-ETHANEDIOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；CRYSTAL WERE OBTAINED BY HANGING DROP METHOD FROM 1MM VEGFR1-D2, 5MM HEPES/NAOH PH7.0, 10MM COCL2, 100 MM BIS-TRIS/HCL PH6.5 15%(W/V) PEG3350.
Resolution 2.00 Å R-free 0.233
4CL7 Crystal structure of VEGFR-1 domain 2 in presence of Cobalt Deposited 2014-01-13 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 132–225（94 aa） Fragment：DOMAIN-2, RESIDUES 132-225
Chain D 132–225（94 aa） Fragment：DOMAIN-2, RESIDUES 132-225
Not recorded CO COBALT (II) ION × 2 EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；CRYSTAL WERE OBTAINED BY HANGING DROP METHOD FROM 1MM VEGFR1-D2, 5MM HEPES/NAOH PH7.0, 10MM COCL2, 100 MM BIS-TRIS/HCL PH6.5 15%(W/V) PEG3350.
Resolution 2.00 Å R-free 0.233
5ABD CRYSTAL STRUCTURE OF VEGFR-1 DOMAIN 2 IN PRESENCE OF CU Deposited 2015-08-05 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 132–226（95 aa） Fragment：DOMAIN-2, RESIDUES 132-226
Not recorded NA SODIUM ION × 1 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；291 K；VAPOR DIFFUSION METHOD, MOTHER LIQUOR: 1.5MICROM VERGFR1-D2, 15MM TRIS/HCL PH 8.1, 25MM NACL, 5MM CUSO4 RESERVOIR: 19.5% (W/V) PEG8000, 100MM SA,
Resolution 2.00 Å R-free 0.222
5ABD CRYSTAL STRUCTURE OF VEGFR-1 DOMAIN 2 IN PRESENCE OF CU Deposited 2015-08-05 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain I 132–226（95 aa） Fragment：DOMAIN-2, RESIDUES 132-226
Not recorded CU COPPER (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；291 K；VAPOR DIFFUSION METHOD, MOTHER LIQUOR: 1.5MICROM VERGFR1-D2, 15MM TRIS/HCL PH 8.1, 25MM NACL, 5MM CUSO4 RESERVOIR: 19.5% (W/V) PEG8000, 100MM SA,
Resolution 2.00 Å R-free 0.222
5ABD CRYSTAL STRUCTURE OF VEGFR-1 DOMAIN 2 IN PRESENCE OF CU Deposited 2015-08-05 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain X 132–226（95 aa） Fragment：DOMAIN-2, RESIDUES 132-226
Not recorded NA SODIUM ION × 1 SO4 SULFATE ION × 1 CU COPPER (II) ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；291 K；VAPOR DIFFUSION METHOD, MOTHER LIQUOR: 1.5MICROM VERGFR1-D2, 15MM TRIS/HCL PH 8.1, 25MM NACL, 5MM CUSO4 RESERVOIR: 19.5% (W/V) PEG8000, 100MM SA,
Resolution 2.00 Å R-free 0.222
5T89 Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6 Deposited 2016-09-07 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain X 27–656（630 aa）
Chain Y 27–656（630 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 19 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；10-14% PEG3000 200 mM calcium chloride 100 mM MES pH 6.5
Resolution 4.00 Å R-free 0.315

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.