Current Protein Identity:P32597 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
6K15 RSC substrate-recruitment module Deposited 2019-05-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: tridecameric(13) Consistent with protein count
Chain J 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1248–1359(112 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
Resolution 2.40 Å R-free 0.242
6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 1248–1359(112 aa)
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
Resolution 2.40 Å R-free 0.242
6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 1248–1359(112 aa)
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
Resolution 2.40 Å R-free 0.242
6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 1248–1359(112 aa)
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
Resolution 2.40 Å R-free 0.242
6KMJ Crystal structure of Sth1 bromodomain in complex with H3K14Ac Deposited 2019-07-31 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1248–1359(112 aa)
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;1% w/v tryptone, 1 mM sodium azide, 50 mM HEPES sodium pH 7.0, 20% w/v PEG 3350
Resolution 1.40 Å R-free 0.188
6KW3 The ClassA RSC-Nucleosome Complex Deposited 2019-09-05 Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers
Chain J 1–1359(1359 aa)
Chain W 1–1359(1359 aa)
Chain Y 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.13 Å
6KW4 The ClassB RSC-Nucleosome Complex Deposited 2019-09-06 Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers
Chain J 1–1359(1359 aa)
Chain V 1–1359(1359 aa)
Chain Y 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.55 Å
6KW5 The ClassC RSC-Nucleosome Complex Deposited 2019-09-06 Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers
Chain J 1–1359(1359 aa)
Chain P 1–1359(1359 aa)
Chain Q 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 10.13 Å
6LQZ Solution structure of Taf14ET-Sth1EBMC Deposited 2020-01-15 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 1183–1240(58 aa) Fragment:Sth1EBMC
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7;298 K;Ionic strength (raw mmCIF value) 100;Pressure 1
NMR sample composition 1 mM [U-100% 13C; U-100% 15N] Taf14ET, 1.5 mM [U-100% 13C; U-100% 15N] Sth1EBMC, 20 mM Phosphate buffer, 100 mM sodium chloride, 1 % v/v inhabitor cocktail, 0.04 % sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 10 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain D 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain E 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain F 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 7 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1250–1359(110 aa)
Chain F 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 8 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 Assembly 9 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain C 1250–1359(110 aa)
Chain E 1250–1359(110 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate 0.1 M BIS-TRIS pH 6.5 25% (w/v) Polyethylene glycol 3350 3% Trimethylamine N-oxide dihydrate
Resolution 2.71 Å R-free 0.270
6TDA Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome Deposited 2019-11-08 Assembly 1 Protein–DNA Heteromer;Protein × 21 PDB declaration: 23-meric(23) Consistent with all polymers
Chain S 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 15.00 Å
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain E 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain F 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain G 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 Assembly 8 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain H 1250–1359(110 aa) Fragment:bromodomain
Non-standard monomer:Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5 0.2 M magnesium chloride hexahydrate 25% (w/v) Polyethylene glycol 3350
Resolution 2.21 Å R-free 0.228
6V8O RSC core Deposited 2019-12-11 Assembly 1 Protein heterocomplex Heteromer;Protein × 22 PDB declaration: 22-meric(22) Consistent with protein count
Chain R 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.07 Å
6V92 RSC-NCP Deposited 2019-12-13 Assembly 1 Protein–DNA Heteromer;Protein × 33 PDB declaration: 35-meric(35) Consistent with all polymers
Chain R 1–1359(1359 aa)
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 20.00 Å
6VZ4 Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102 bound to the nucleosome in ADP Beryllium Fluoride state Deposited 2020-02-27 Assembly 1 Protein–DNA Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers
Chain K 301–1097(797 aa)
Not recorded MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE;4 second blot time, blot force 20
Resolution 3.90 Å
6VZG Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102 Deposited 2020-02-28 Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain K 301–1097(797 aa)
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE;4 second blot time, blot force 20
Resolution 4.20 Å
7F3S Crystal structure of Sth1 Bromodomain in complex with H3K14bz peptide Deposited 2021-06-17 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 1248–1359(112 aa)
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5;289 K;25% (w/v) PEG 1500, 0.1M MIB/Hydrochloric acid
Resolution 1.40 Å R-free 0.182