Current Protein Identity:P32597
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 6K15 RSC substrate-recruitment module Deposited 2019-05-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: tridecameric(13) Consistent with protein count |
Chain J
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1248–1359(112 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
|
Resolution 2.40 Å R-free 0.242 |
| 6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1248–1359(112 aa)
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
|
Resolution 2.40 Å R-free 0.242 |
| 6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
1248–1359(112 aa)
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
|
Resolution 2.40 Å R-free 0.242 |
| 6KMB Crystal structure of Sth1 bromodomain Deposited 2019-07-31 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
1248–1359(112 aa)
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;0.2 M sodium formate, pH 7.0, 20% w/v PEG 3350
|
Resolution 2.40 Å R-free 0.242 |
| 6KMJ Crystal structure of Sth1 bromodomain in complex with H3K14Ac Deposited 2019-07-31 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1248–1359(112 aa)
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;1% w/v tryptone, 1 mM sodium azide, 50 mM HEPES sodium pH 7.0, 20% w/v PEG 3350
|
Resolution 1.40 Å R-free 0.188 |
| 6KW3 The ClassA RSC-Nucleosome Complex Deposited 2019-09-05 | Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers |
Chain J
1–1359(1359 aa)
Chain W
1–1359(1359 aa)
Chain Y
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 7.13 Å |
| 6KW4 The ClassB RSC-Nucleosome Complex Deposited 2019-09-06 | Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers |
Chain J
1–1359(1359 aa)
Chain V
1–1359(1359 aa)
Chain Y
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 7.55 Å |
| 6KW5 The ClassC RSC-Nucleosome Complex Deposited 2019-09-06 | Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers |
Chain J
1–1359(1359 aa)
Chain P
1–1359(1359 aa)
Chain Q
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 10.13 Å |
| 6LQZ Solution structure of Taf14ET-Sth1EBMC Deposited 2020-01-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
1183–1240(58 aa)
Fragment:Sth1EBMC
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;298 K;Ionic strength (raw mmCIF value) 100;Pressure 1
NMR sample composition
1 mM [U-100% 13C; U-100% 15N] Taf14ET, 1.5 mM [U-100% 13C; U-100% 15N] Sth1EBMC, 20 mM Phosphate buffer, 100 mM sodium chloride, 1 % v/v inhabitor cocktail, 0.04 % sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 10 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain E
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain F
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 7 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1250–1359(110 aa)
Chain F
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 8 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6MR4 Crystal structure of the Sth1 bromodomain from S.cerevisiae Deposited 2018-10-11 | Assembly 9 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
1250–1359(110 aa)
Chain E
1250–1359(110 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;293 K;0.2 M magnesium chloride hexahydrate
0.1 M BIS-TRIS pH 6.5
25% (w/v) Polyethylene glycol 3350
3% Trimethylamine N-oxide dihydrate
|
Resolution 2.71 Å R-free 0.270 |
| 6TDA Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome Deposited 2019-11-08 | Assembly 1 Protein–DNA Heteromer;Protein × 21 PDB declaration: 23-meric(23) Consistent with all polymers |
Chain S
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 15.00 Å |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 5 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain E
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 6 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain F
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 7 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain G
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6UY1 Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution Deposited 2019-11-09 | Assembly 8 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain H
1250–1359(110 aa)
Fragment:bromodomain
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1 M BIS-TRIS pH 6.5
0.2 M magnesium chloride hexahydrate
25% (w/v) Polyethylene glycol 3350
|
Resolution 2.21 Å R-free 0.228 |
| 6V8O RSC core Deposited 2019-12-11 | Assembly 1 Protein heterocomplex Heteromer;Protein × 22 PDB declaration: 22-meric(22) Consistent with protein count |
Chain R
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.07 Å |
| 6V92 RSC-NCP Deposited 2019-12-13 | Assembly 1 Protein–DNA Heteromer;Protein × 33 PDB declaration: 35-meric(35) Consistent with all polymers |
Chain R
1–1359(1359 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 20.00 Å |
| 6VZ4 Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102 bound to the nucleosome in ADP Beryllium Fluoride state Deposited 2020-02-27 | Assembly 1 Protein–DNA Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers |
Chain K
301–1097(797 aa)
|
Not recorded | MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE;4 second blot time, blot force 20
|
Resolution 3.90 Å |
| 6VZG Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102 Deposited 2020-02-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain K
301–1097(797 aa)
|
Not recorded | ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE;4 second blot time, blot force 20
|
Resolution 4.20 Å |
| 7F3S Crystal structure of Sth1 Bromodomain in complex with H3K14bz peptide Deposited 2021-06-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1248–1359(112 aa)
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5;289 K;25% (w/v) PEG 1500, 0.1M MIB/Hydrochloric acid
|
Resolution 1.40 Å R-free 0.182 |