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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P40394 New Search
3PDB entries
12Biological assembly
32chain/assembly records
Main Difference Dimensions in This Set
Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1AGN X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE Deposited 1996-06-04 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Not recorded ZN ZINC ION × 8 ACT ACETATE ION × 7 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å R-free 0.305
1AGN X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE Deposited 1996-06-04 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 8 ACT ACETATE ION × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å R-free 0.305
1AGN X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE Deposited 1996-06-04 Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 16 ACT ACETATE ION × 10 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å R-free 0.305
1AGN X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE Deposited 1996-06-04 Assembly 4 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 16 ACT ACETATE ION × 10 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å R-free 0.305
1D1S WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE Deposited 1999-09-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 19 ACT ACETATE ION × 13 CAC CACODYLATE ION × 5 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 MM CACODYLATE, 100 MM ZINC ACETATE, 7.5 MM NAD+, 18% POLYETHYLENE GLYCOL 6000, 8 MG/ML ENZYME, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.50 Å R-free 0.268
1D1S WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE Deposited 1999-09-21 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 10 ACT ACETATE ION × 7 CAC CACODYLATE ION × 4 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 MM CACODYLATE, 100 MM ZINC ACETATE, 7.5 MM NAD+, 18% POLYETHYLENE GLYCOL 6000, 8 MG/ML ENZYME, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.50 Å R-free 0.268
1D1S WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE Deposited 1999-09-21 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Not recorded ZN ZINC ION × 11 ACT ACETATE ION × 6 CAC CACODYLATE ION × 5 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 MM CACODYLATE, 100 MM ZINC ACETATE, 7.5 MM NAD+, 18% POLYETHYLENE GLYCOL 6000, 8 MG/ML ENZYME, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.50 Å R-free 0.268
1D1S WILD-TYPE HUMAN SIGMA (CLASS IV) ALCOHOL DEHYDROGENASE Deposited 1999-09-21 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Not recorded ZN ZINC ION × 8 ACT ACETATE ION × 7 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 MM CACODYLATE, 100 MM ZINC ACETATE, 7.5 MM NAD+, 18% POLYETHYLENE GLYCOL 6000, 8 MG/ML ENZYME, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.50 Å R-free 0.268
1D1T MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141 Deposited 1999-09-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Mutation：M141L Mutation：M141L Mutation：M141L Mutation：M141L ZN ZINC ION × 19 ACT ACETATE ION × 13 CAC CACODYLATE ION × 5 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM Cacodylate, pH 6.5, 100 mM Zinc Acetate, 7.5 mM NAD+, 18% PEG 6000, 8 mg/ml enzyme, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.274
1D1T MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141 Deposited 1999-09-21 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 2–374（373 aa）
Chain D 2–374（373 aa）
Mutation：M141L Mutation：M141L ZN ZINC ION × 10 ACT ACETATE ION × 7 CAC CACODYLATE ION × 4 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM Cacodylate, pH 6.5, 100 mM Zinc Acetate, 7.5 mM NAD+, 18% PEG 6000, 8 mg/ml enzyme, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.274
1D1T MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141 Deposited 1999-09-21 Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2–374（373 aa）
Chain B 2–374（373 aa）
Mutation：M141L Mutation：M141L ZN ZINC ION × 11 ACT ACETATE ION × 6 CAC CACODYLATE ION × 5 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM Cacodylate, pH 6.5, 100 mM Zinc Acetate, 7.5 mM NAD+, 18% PEG 6000, 8 mg/ml enzyme, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.274
1D1T MUTANT OF HUMAN SIGMA ALCOHOL DEHYDROGENASE WITH LEUCINE AT POSITION 141 Deposited 1999-09-21 Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 2–374（373 aa）
Chain D 2–374（373 aa）
Mutation：M141L Mutation：M141L ZN ZINC ION × 8 ACT ACETATE ION × 7 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM Cacodylate, pH 6.5, 100 mM Zinc Acetate, 7.5 mM NAD+, 18% PEG 6000, 8 mg/ml enzyme, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.274

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.