Current Protein Identity:P42081
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1I85 CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX Deposited 2001-03-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
26–134(109 aa)
Fragment:IG V-TYPE (RECEPTOR BINDING) DOMAIN
Chain B
26–134(109 aa)
Fragment:IG V-TYPE (RECEPTOR BINDING) DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;298 K;PEG20K, HEPES, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 3.20 Å R-free 0.300 |
| 1NCN the receptor-binding domain of human B7-2 Deposited 2002-12-05 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
26–134(109 aa)
Fragment:Ig V-type domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;277 K;PEG4000, NaAC, Tris-HCl, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.70 Å R-free 0.278 |
| 1NCN the receptor-binding domain of human B7-2 Deposited 2002-12-05 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
26–134(109 aa)
Fragment:Ig V-type domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;277 K;PEG4000, NaAC, Tris-HCl, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.70 Å R-free 0.278 |
| 5YXK High resolution crystal structure of Human B7-2 IgV domain in P21 space group Deposited 2017-12-05 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
26–134(109 aa)
Fragment:Ig-like V-type
Chain B
26–134(109 aa)
Fragment:Ig-like V-type
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;298 K;0.1M Tris HCl pH 8.5, 2.4M Ammonium phosphate dibasic
|
Resolution 1.90 Å R-free 0.248 |
| 5YXK High resolution crystal structure of Human B7-2 IgV domain in P21 space group Deposited 2017-12-05 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
26–134(109 aa)
Fragment:Ig-like V-type
Chain D
26–134(109 aa)
Fragment:Ig-like V-type
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;298 K;0.1M Tris HCl pH 8.5, 2.4M Ammonium phosphate dibasic
|
Resolution 1.90 Å R-free 0.248 |
| 8FXX Cryo-EM structure of cowpox virus M2 in complex with human B7.2 (heptameric ring) Deposited 2023-01-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 14 PDB declaration: tetradecameric(14) Consistent with protein count |
Chain C
26–134(109 aa)
Chain E
26–134(109 aa)
Chain G
26–134(109 aa)
Chain H
26–134(109 aa)
Chain J
26–134(109 aa)
Chain L
26–134(109 aa)
Chain N
26–134(109 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 21 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;150 mM Nacl, 25 mM HEPES, pH7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.26 Å |
| 8FXY Cryo-EM structure of cowpox virus M2 in complex with human B7.2 (hexameric ring) Deposited 2023-01-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain C
26–243(218 aa)
Chain E
26–243(218 aa)
Chain G
26–243(218 aa)
Chain H
26–243(218 aa)
Chain J
26–243(218 aa)
Chain L
26–243(218 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 18 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4;150 mM Nacl, 25 mM HEPES, pH7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.34 Å |
| 8HXB Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2 Deposited 2023-01-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain G
26–238(213 aa)
Chain H
26–238(213 aa)
Chain I
26–238(213 aa)
Chain J
26–238(213 aa)
Chain K
26–238(213 aa)
Chain L
26–238(213 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å |
| 8HXC Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2 Deposited 2023-01-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 14 PDB declaration: tetradecameric(14) Consistent with protein count |
Chain H
26–238(213 aa)
Chain I
26–238(213 aa)
Chain J
26–238(213 aa)
Chain K
26–238(213 aa)
Chain L
26–238(213 aa)
Chain M
26–238(213 aa)
Chain N
26–238(213 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.12 Å |