Current Protein Identity:P55957
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1ZY3 Structural model of complex of Bcl-w protein with Bid BH3-peptide Deposited 2005-06-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
82–101(20 aa)
|
Mutation:R203K | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;303 K;Ionic strength (raw mmCIF value) 10 mM NaCl;Pressure 1
NMR sample composition
0.7 mM Bcl-w U-15N,13C, 0.7 mM Bid BH3-peptide, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7 mM Bcl-w U-15N, 0.7 mM Bid BH3-peptide, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7 mM Bid BH3-peptide U-15N, 0.7 mM Bcl-w, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2BID HUMAN PRO-APOPTOTIC PROTEIN BID Deposited 1999-01-27 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–195(195 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5;298 K;Pressure 1
|
Resolution not provided |
| 2KBW Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide Deposited 2008-12-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
76–106(31 aa)
Fragment:BH3 motif, residues 76-106
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5;303 K;Ionic strength (raw mmCIF value) 20;Pressure ambient
NMR sample composition
0.5 mM [U-95% 15N] Mcl-1-1, 0.5 mM Bid_BH3-2, 20 mM HEPES-3, 1 mM DTT-4, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM Mcl-1-5, 0.5 mM [U-95% 15N] Bid_BH3-6, 20 mM HEPES-7, 1 mM DTT-8, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM [U-95% 13C; U-95% 15N] Mcl-1-9, 0.5 mM Bid_BH3-10, 20 mM HEPES-11, 1 mM DTT-12, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM [U-95% 13C; U-95% 15N] Mcl-1-13, 0.5 mM Bid_BH3-14, 20 mM HEPES-15, 1 mM DTT-16, 100 % [U-100% 2H] D2O-17, 100% D2O | 100% D2O
NMR sample composition
0.5 mM Mcl-1-18, 0.5 mM [U-95% 13C; U-95% 15N] Bid_BH3-19, 20 mM HEPES-20, 1 mM DTT-21, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM Mcl-1-22, 0.5 mM [U-95% 13C; U-95% 15N] Bid_BH3-23, 20 mM HEPES-24, 1 mM DTT-25, 100 % [U-100% 2H] D2O-26, 100% D2O | 100% D2O
NMR sample composition
0.4 mM [U-95% 15N] Mcl-1-27, 0.4 mM Bid_BH3-28, 20 mM HEPES-29, 1 mM DTT-30, 6 mg/mL Pf1 phage-31, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.4 mM Mcl-1-32, 0.4 mM [U-95% 15N] Bid_BH3-33, 20 mM HEPES-34, 1 mM DTT-35, 8 mg/mL Pf1 phage-36, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2M5I NMR structures of human apoptotic protein tBid in LPPG micelle Deposited 2013-02-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
61–195(135 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.6;318 K;Ionic strength (raw mmCIF value) 0.1;Pressure ambient
NMR sample composition
0.5 mM [U-15N] tBid in LPPG micelle, 0.8 mM [U-13C; U-15N] tBid in LPPG micelle, 0.8 mM [U-100% 15N; U-80% 2H] tBid in LPPG micelle, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.0 mM [U-100% 13C; U-100% 15N] tBid in LPPG micelle, 100% D2O | 100% D2O
|
Resolution not provided |
| 4BD2 Bax domain swapped dimer in complex with BidBH3 Deposited 2012-10-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
76–109(34 aa)
Fragment:RESIDUES 76-109
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
1.4 M SODIUM CITRATE, 0.1 M SODIUM CACODYLATE PH 5.75
|
Resolution 2.21 Å R-free 0.227 |
| 4QVE Crystal structure of Bcl-xL in complex with BID BH3 domain Deposited 2014-07-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
76–109(34 aa)
Fragment:BID BH3, UNP RESIDUES 76-109
|
Not recorded | IMD IMIDAZOLE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 10.5;291 K;2.0M Ammonium Sulphate, 0.2M Lithium Sulphate, 0.1M CAPS pH 10.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.05 Å R-free 0.224 |
| 4ZEQ Crystal Structure of human BFL-1 in complex with tBid BH3 peptide, Northeast Structural Genomics Consortium Target HX9247 Deposited 2015-04-20 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
125–150(26 aa)
Fragment:UNP Residues 125-150
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.4;295 K;Sodium Malonate
|
Resolution 1.80 Å R-free 0.239 |
| 4ZIG Crystal Structure of core/latch dimer of Bax in complex with BidBH3mini Deposited 2015-04-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain B
125–144(20 aa)
Fragment:BH3 motif
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;277 K;Tri-sodium citrate, Sodium cacodylate
|
Resolution 2.20 Å R-free 0.229 |
| 4ZII Crystal Structure of core/latch dimer of BaxI66A in complex with BidBH3 Deposited 2015-04-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
122–155(34 aa)
Fragment:BH3 motif
|
Not recorded | EDO 1,2-ETHANEDIOL × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;277 K;Tri-sodium citrate, sodium cacodylate
|
Resolution 2.19 Å R-free 0.223 |
| 5AJJ Crystal structure of variola virus virulence factor F1L in complex with human Bid BH3 domain Deposited 2015-02-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain B
79–112(34 aa)
Fragment:UNP RESIDUES 79-112
|
Not recorded | GOL GLYCEROL × 2 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;1.8 M SODIUM ACETATE AND 0.1 M HEPES PH 6.5
|
Resolution 1.75 Å R-free 0.208 |
| 7M5A Crystal Structure of human BAK in complex with W3W5_BID Deposited 2021-03-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
80–100(21 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;293 K;0.2 M Potassium Sodium tartrate, 20% PEG 3350
|
Resolution 1.50 Å R-free 0.219 |
| 7M5B Crystal Structure of human BAK in complex with M3W5_BID Deposited 2021-03-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
80–100(21 aa)
|
Not recorded | CU COPPER (II) ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 6.5;293 K;15% PEG 4000 0.2 M NaCl 0.1 MES 6.5
|
Resolution 1.85 Å R-free 0.205 |
| 7M5B Crystal Structure of human BAK in complex with M3W5_BID Deposited 2021-03-23 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
80–100(21 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 6.5;293 K;15% PEG 4000 0.2 M NaCl 0.1 MES 6.5
|
Resolution 1.85 Å R-free 0.205 |
| 7P33 Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide Deposited 2021-07-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain G
76–109(34 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.4M Ammonium phosphate mono basic
|
Resolution 2.79 Å R-free 0.274 |
| 7P33 Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide Deposited 2021-07-07 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
76–109(34 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.4M Ammonium phosphate mono basic
|
Resolution 2.79 Å R-free 0.274 |
| 7P33 Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide Deposited 2021-07-07 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain H
76–109(34 aa)
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.4M Ammonium phosphate mono basic
|
Resolution 2.79 Å R-free 0.274 |
| 7P33 Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide Deposited 2021-07-07 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain I
76–109(34 aa)
|
Not recorded | PO4 PHOSPHATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.4M Ammonium phosphate mono basic
|
Resolution 2.79 Å R-free 0.274 |
| 7P33 Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide Deposited 2021-07-07 | Assembly 5 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain J
76–109(34 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;0.4M Ammonium phosphate mono basic
|
Resolution 2.79 Å R-free 0.274 |
| 7QTW Kaposi sarcoma associated herpes virus(KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Bid BH3 Deposited 2022-01-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
76–109(34 aa)
|
Not recorded | EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4.6;293 K;0.1 M Sodium acetate pH 4.6
8% PEG 4000
|
Resolution 1.41 Å R-free 0.215 |