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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q64373 New Search
16PDB entries
21Biological assembly
23chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1PQ0 Crystal structure of mouse Bcl-xl Deposited 2003-06-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：Bcl-xl
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；NH4SO4, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.20 Å R-free 0.243
1PQ1 Crystal structure of Bcl-xl/Bim Deposited 2003-06-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–196（196 aa） Fragment：BIM
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；NH4H2PO4, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.65 Å R-free 0.237
2BZW The crystal structure of BCL-XL in complex with full-length BAD Deposited 2005-08-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–211（211 aa） Fragment：BCL-2 HOMOLOGY DOMAIN, RESIDUES 1-211
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.30 Å R-free 0.248
3IHC Crystal structure of mouse Bcl-xl (wt) at pH 5.0 Deposited 2009-07-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.6M Ammonium sulphate, Tri-Na citrate (pH 5.0), VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 1.85 Å R-free 0.242
3IHD Crystal structure of mouse Bcl-xl mutant (Y101A) at pH 5.0 Deposited 2009-07-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：Y101A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.4M Ammonium Sulphate, Tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 1.88 Å R-free 0.210
3IHE Crystal structure of mouse Bcl-xl mutant (F105A) at pH 6.0 Deposited 2009-07-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：F105A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；1.7M Ammonium sulphate, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 3.00 Å R-free 0.239
3IHF Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0 Deposited 2009-07-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.45M Ammonium sulphate, Tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.28 Å R-free 0.266
3IHF Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0 Deposited 2009-07-30 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.45M Ammonium sulphate, Tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.28 Å R-free 0.266
3IHF Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0 Deposited 2009-07-30 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.45M Ammonium sulphate, Tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.28 Å R-free 0.266
3IHF Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0 Deposited 2009-07-30 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.45M Ammonium sulphate, Tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.28 Å R-free 0.266
3IIG Crystal structure of mouse Bcl-xl mutant (F105A) at pH 5.0 Deposited 2009-08-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：F105A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；295 K；1.6M Ammonium sulphate, 0.1M tri-Na citrate, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.30 Å R-free 0.269
3IIH Crystal structure of mouse Bcl-xl (wt) at pH 6.0 Deposited 2009-08-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；295 K；1.0M Ammonium sulphate, 0.4M Lithium sulphate, MES, pH 6.0, VAPOR DIFFUSION, SITTING DROP, temperature 295K
Resolution 2.75 Å R-free 0.275
3ILB Crystal structure of mouse Bcl-xl mutant (R139A) at pH 6.0 Deposited 2009-08-07 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；1.2M Ammonium sulphate, 0.3M Lithium sulphate, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.38 Å R-free 0.293
3ILB Crystal structure of mouse Bcl-xl mutant (R139A) at pH 6.0 Deposited 2009-08-07 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain N 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：R139A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；1.2M Ammonium sulphate, 0.3M Lithium sulphate, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 2.38 Å R-free 0.293
3ILC Crystal structure of mouse Bcl-xl mutant (Y101A) at pH 6.0 Deposited 2009-08-07 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–196（196 aa） Fragment：UNP residues 1-196
Mutation：Y101A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；295 K；1.6M Ammonium sulphate, MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 295K
Resolution 1.64 Å R-free 0.244
4YJ4 Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations Deposited 2015-03-03 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–196（196 aa）
Mutation：M83E, A84S ACT ACETATE ION × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.8；293 K；0.1 M sodium acetate (pH 4.8), 3.0 M sodium chloride
Resolution 2.10 Å R-free 0.211
4YK9 Complex structure of BCL-XL and mutated BIM BH3 domain Deposited 2015-03-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2–196（195 aa） Fragment：UNP RESIDUES 2-196
Not recorded ACT ACETATE ION × 2 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；287 K；0.1 M sodium acetate (pH 4.6), 0.01 M calcium chloride and 15% v/v 2-methyl-2,4-pentanediol
Resolution 1.70 Å R-free 0.228
4YK9 Complex structure of BCL-XL and mutated BIM BH3 domain Deposited 2015-03-04 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 2–196（195 aa） Fragment：UNP RESIDUES 2-196
Not recorded ACT ACETATE ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；287 K；0.1 M sodium acetate (pH 4.6), 0.01 M calcium chloride and 15% v/v 2-methyl-2,4-pentanediol
Resolution 1.70 Å R-free 0.228
5C3G Crystal structure of Bcl-xl bound to BIM-MM Deposited 2015-06-17 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–26（26 aa） Fragment：UNP residues 1-26,UNP residues 83-209
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；12% Peg 1500, 0.1M Sodium Acetate pH 5.5, 2.5M NaCl, 1.5% MPD
Resolution 2.45 Å R-free 0.274
7WJH Crystal structure of Bcl-xL bound to the BH3 domain of human Pxt1 Deposited 2022-01-06 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–42（42 aa）
Chain A 85–196（112 aa）
Not recorded SO4 SULFATE ION × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；0.2 M ammonium sulfate and 30% (w/v) polyethylene glycol 8,000
Resolution 1.70 Å R-free 0.207
7Y99 Crystal Structure Analysis of cp2 bound BCLxl Deposited 2022-06-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–26（26 aa）
Chain A 82–196（115 aa）
Not recorded IQ8 N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；277 K；Ammonium acetate, BIS-TRIS, MPD
Resolution 1.90 Å R-free 0.192

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.