Current Protein Identity:Q80TS3
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4RMK Crystal structure of the Olfactomedin domain of latrophilin 3 in P65 crystal form Deposited 2014-10-21 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
199–495(297 aa)
Fragment:Olfactomedin Domain (199-495)
|
Not recorded | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Microbach under-oil;pH 9;293 K;15-25 % PEG 8000, 50-300 mM MgCl2, 100 mM TAPS pH 9.0, Microbach under-oil, temperature 293K
|
Resolution 1.61 Å R-free 0.190 |
| 4RML Crystal structure of the Olfactomedin domain of latrophilin 3 in C2221 crystal form Deposited 2014-10-21 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
199–495(297 aa)
Fragment:Olfactomedin Domain (199-495)
|
Not recorded | MG MAGNESIUM ION × 1 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Microbach under-oil;pH 9;293 K;15-25 % PEG 8000, 50-300 mM MgCl2, 100 mM TAPS pH 9.0
, Microbach under-oil, temperature 293K
|
Resolution 1.60 Å R-free 0.196 |
| 4YEB Structural characterization of a synaptic adhesion complex Deposited 2015-02-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
199–495(297 aa)
|
Not recorded | CA CALCIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;6 % PEG 3350, 0.2 M NaNO3
|
Resolution 3.19 Å R-free 0.336 |
| 5AFB Crystal structure of the Latrophilin3 Lectin and Olfactomedin Domains Deposited 2015-01-21 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS, RESIDUES 97-459
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 NA SODIUM ION × 4 CA CALCIUM ION × 4 GOL GLYCEROL × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6;0.1 M MES BUFFER, 4M NACL, 0.6 M NON- DETERGENT SULFO-BETAINE NDSB195, PH 6.0
|
Resolution 2.16 Å R-free 0.245 |
| 5FTT Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR) Deposited 2016-01-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count |
Chain C
92–463(372 aa)
Chain D
92–463(372 aa)
Chain G
92–463(372 aa)
Chain H
92–463(372 aa)
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 NA SODIUM ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6;pH 6.0
|
Resolution 3.40 Å R-free 0.245 |
| 5FTU Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 Deposited 2016-01-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
Chain D
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 NA SODIUM ION × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.5
|
Resolution 6.01 Å R-free 0.278 |
| 5FTU Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 Deposited 2016-01-15 | Assembly 2 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain G
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
Chain H
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 NA SODIUM ION × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.5
|
Resolution 6.01 Å R-free 0.278 |
| 5FTU Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 Deposited 2016-01-15 | Assembly 3 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain K
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
Chain L
92–463(372 aa)
Fragment:LECTIN AND OLFACTOMEDIN DOMAINS
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 NA SODIUM ION × 2 CA CALCIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.5
|
Resolution 6.01 Å R-free 0.278 |
| 6JBU High resolution crystal structure of human FLRT3 LRR domain in complex with mouse CIRL3 Olfactomedin like domain Deposited 2019-01-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
203–461(259 aa)
Fragment:Olfactomedin like domain
|
Not recorded | PO4 PHOSPHATE ION × 2 NA SODIUM ION × 3 EDO 1,2-ETHANEDIOL × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;560 mM sodium monobasic phosphate/potassium dibasic phosphate, 0.1 M Tris pH 8.5, 1.5% MPD
|
Resolution 1.85 Å R-free 0.234 |
| 7WY5 ADGRL3/Gq complex Deposited 2022-02-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain R
1–1543(1543 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å |
| 7WY8 ADGRL3/Gs complex Deposited 2022-02-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain R
1–1543(1543 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å |
| 7WYB ADGRL3/Gi complex Deposited 2022-02-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain R
1–1543(1543 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.97 Å |
| 7X10 ADGRL3/miniG12 complex Deposited 2022-02-22 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain R
1–1543(1543 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.93 Å |