Current Protein Identity:Q9BUL8
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3AJM Crystal structure of programmed cell death 10 in complex with inositol 1,3,4,5-tetrakisphosphate Deposited 2010-06-09 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
8–212(205 aa)
Fragment:UNP residues 8-212
Chain B
8–212(205 aa)
Fragment:UNP residues 8-212
|
Not recorded | 4IP INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6;293 K;30% PEG, 0.1M sodium cacodylate, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 2.30 Å R-free 0.264 |
| 3L8I Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Deposited 2009-12-31 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1M potassium fluoride, 13% PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 2.50 Å R-free 0.288 |
| 3L8I Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Deposited 2009-12-31 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1M potassium fluoride, 13% PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 2.50 Å R-free 0.288 |
| 3L8I Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Deposited 2009-12-31 | Assembly 3 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1M potassium fluoride, 13% PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 2.50 Å R-free 0.288 |
| 3L8I Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Deposited 2009-12-31 | Assembly 4 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.1M potassium fluoride, 13% PEG 3350, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 2.50 Å R-free 0.288 |
| 3L8J Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity Deposited 2009-12-31 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
14–212(199 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;298 K;0.16 M calcium acetate, 0.08 M sodium cacodylate pH 6.5, 20% glycerol, 13.5% PEG 8000, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 3.05 Å R-free 0.293 |
| 3RQE Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1 Deposited 2011-04-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350., pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.80 Å R-free 0.295 |
| 3RQE Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1 Deposited 2011-04-28 | Assembly 2 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350., pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.80 Å R-free 0.295 |
| 3RQE Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1 Deposited 2011-04-28 | Assembly 3 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350., pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.80 Å R-free 0.295 |
| 3RQF Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2 Deposited 2011-04-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.70 Å R-free 0.291 |
| 3RQF Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2 Deposited 2011-04-28 | Assembly 2 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.70 Å R-free 0.291 |
| 3RQF Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2 Deposited 2011-04-28 | Assembly 3 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.70 Å R-free 0.291 |
| 3RQF Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2 Deposited 2011-04-28 | Assembly 4 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.70 Å R-free 0.291 |
| 3RQG Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4 Deposited 2011-04-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.50 Å R-free 0.291 |
| 3RQG Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4 Deposited 2011-04-28 | Assembly 2 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.50 Å R-free 0.291 |
| 3RQG Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4 Deposited 2011-04-28 | Assembly 3 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.50 Å R-free 0.291 |
| 3RQG Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4 Deposited 2011-04-28 | Assembly 4 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;298 K;0.1-0.2 M potassium fluoride,
15-20% PEG3350, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.50 Å R-free 0.291 |
| 3W8H Crystal structure of CCM3 in complex with the C-terminal regulatory domain of STK25 Deposited 2013-03-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
8–212(205 aa)
Fragment:UNP RESIDUES 8-212
|
Not recorded | SO4 SULFATE ION × 14 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;293 K;0.1M Bis-Tris, 25% PEG3350, 0.2M ammonium sulfate, pH 5.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.43 Å R-free 0.264 |
| 3W8I Crystal structure of CCM3 in complex with the C-terminal regulatory domain of MST4 Deposited 2013-03-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
8–212(205 aa)
Fragment:UNP RESIDUES 8-212
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6;293 K;0.1M Bis-Tris, 25% PEG3350, 0.3M ammonium acetate, pH 6.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.267 |
| 4GEH Crystal structure of MST4 dimerization domain complex with PDCD10 Deposited 2012-08-02 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
9–212(204 aa)
Fragment:UNP residues 9-212
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;289 K;2% v/v Tacsimate pH 6.0, 0.1M BIS-TRIS pH 6.5, 18% w/v PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.95 Å R-free 0.253 |
| 4GEH Crystal structure of MST4 dimerization domain complex with PDCD10 Deposited 2012-08-02 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
9–212(204 aa)
Fragment:UNP residues 9-212
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;289 K;2% v/v Tacsimate pH 6.0, 0.1M BIS-TRIS pH 6.5, 18% w/v PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.95 Å R-free 0.253 |
| 4TVQ CCM3 in complex with CCM2 LD-like motif Deposited 2014-06-27 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–212(212 aa)
Chain B
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;298 K;15-20% PEG3350, 0.1-0.2M POTASSIUM
FLUORIDE, PH 7.0, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298K
|
Resolution 2.80 Å R-free 0.277 |
| 4TVQ CCM3 in complex with CCM2 LD-like motif Deposited 2014-06-27 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
1–212(212 aa)
Chain D
1–212(212 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;298 K;15-20% PEG3350, 0.1-0.2M POTASSIUM
FLUORIDE, PH 7.0, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298K
|
Resolution 2.80 Å R-free 0.277 |