Current Protein Identity：Q9BXH1
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2M04 Solution structure of BCL-xL in complex with PUMA BH3 peptide Deposited 2012-10-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
130–154（25 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298.1 K；Ionic strength (raw mmCIF value) 50；Pressure ambient
NMR sample composition
0.9 mM [U-100% 13C; U-100% 15N; U-95% 2H; Ile,Leu,Val C1H3] BCL-xL, 0.9 mM PUMA BH3, 92% H2O/8% D2O | 92% H2O/8% D2O
NMR sample composition
0.9 mM [U-100% 13C; U-100% 15N] BCL-xL, 0.9 mM PUMA BH3, 92% H2O/8% D2O | 92% H2O/8% D2O
|
Resolution not provided |
| 4HNJ Crystallographic structure of BCL-xL domain-swapped dimer in complex with PUMA BH3 peptide at 2.9A resolution Deposited 2012-10-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
130–154（25 aa）
Fragment：BH3 domain peptide
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；291 K；0.2 M CaCl2, 0.1 M NaOAc, 20% V/V isopropanol, pH 4.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.254 |
| 5UUL Human Bfl-1 in complex with PUMA BH3 Deposited 2017-02-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
132–154（23 aa）
Fragment：UNP residues 132-154
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；1.8 M ammonium sulfate, 0.1 M MES pH 7.0
|
Resolution 1.33 Å R-free 0.155 |
| 6QFM Structure of human Mcl-1 in complex with PUMA BH3 peptide Deposited 2019-01-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
127–149（23 aa）
|
Not recorded | ZN ZINC ION × 3 CL CHLORIDE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；100 mM imidazole buffer pH 7.0, 50 mM zinc acetate and 20-25% polyethylene glycol (PEG) 3350
|
Resolution 2.00 Å R-free 0.261 |
| 6QG8 Structure of human Bcl-2 in complex with PUMA BH3 peptide Deposited 2019-01-10 | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
127–149（23 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；284 K；from 0.2M MgCl2, 25% PegMME 2k, 0.1M Na Acetate buffer pH 5.5
|
Resolution 1.90 Å R-free 0.216 |
| 6TQP Structural insight into tanapoxvirus mediated inhibition of apoptosis Deposited 2019-12-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
130–155（26 aa）
|
Not recorded | NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；0.1 M Potassium thiocyanate, 30% PEG 2000MME
|
Resolution 1.85 Å R-free 0.218 |
| 7DVD The crystal structure of p53 DNA binding domain and PUMA complex Deposited 2021-01-13 | Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain E
136–150（15 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293.15 K；0.1 M Tris (pH 7.0)
20% (w/w) PEG-200 MME
|
Resolution 2.59 Å R-free 0.318 |
| 7P0S ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide Deposited 2021-06-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
130–155（26 aa）
Chain U
130–155（26 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M Magnesium acetate, 25% PEG 3350
|
Resolution 2.50 Å R-free 0.286 |
| 7P9W Epstein-Barr virus encoded apoptosis regulator BHRF1 in complex with Puma BH3 Deposited 2021-07-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
130–155（26 aa）
|
Not recorded | PO4 PHOSPHATE ION × 3 EDO 1,2-ETHANEDIOL × 6 NH4 AMMONIUM ION × 1 PDO 1,3-PROPANDIOL × 2 MG MAGNESIUM ION × 5 CL CHLORIDE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.4 M Ammonium phosphate monobasic
|
Resolution 2.00 Å R-free 0.257 |
| 7QTX Kaposi sarcoma associated herpes virus (KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Puma BH3 Deposited 2022-01-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
130–155（26 aa）
|
Not recorded | BR BROMIDE ION × 3 EDO 1,2-ETHANEDIOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；0.2 M sodium bromide, 0.1 M Bis-tris propane pH 6.5, 20% PEG 3350
|
Resolution 2.12 Å R-free 0.257 |