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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9UKK3 New Search
12PDB entries
26Biological assembly
36chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
11JF RNA Vault bound to PARP4 MINT, focused refinement (MVP/PARP4/TEP1 NADP sample) Deposited 2026-02-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain P 1–1724（1724 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8；50 Tris 8.0, 75 mM NaCl, 1.5 mM MgCl2, 1 mM DTT, 1 mM NADP, 0.025% DDM
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.85 Å
8SWY PARP4 ART domain bound to NADH Deposited 2023-05-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 242–282（41 aa）
Chain A 365–573（209 aa）
Not recorded NAI 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；21% PEG3350, 0.2M sodium citrate tribasic dihydrate, 1% ethylene glycol, 800uM NADH
Resolution 2.55 Å R-free 0.254
8SWY PARP4 ART domain bound to NADH Deposited 2023-05-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 242–282（41 aa）
Chain B 365–573（209 aa）
Not recorded NAI 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；21% PEG3350, 0.2M sodium citrate tribasic dihydrate, 1% ethylene glycol, 800uM NADH
Resolution 2.55 Å R-free 0.254
8SWY PARP4 ART domain bound to NADH Deposited 2023-05-19 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 242–282（41 aa）
Chain C 365–573（209 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；21% PEG3350, 0.2M sodium citrate tribasic dihydrate, 1% ethylene glycol, 800uM NADH
Resolution 2.55 Å R-free 0.254
8SWZ PARP4 ART domain bound to EB47 Deposited 2023-05-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 242–282（41 aa）
Chain A 365–573（209 aa）
Not recorded GOL GLYCEROL × 1 UHB 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；20% PEG3350, 0.2M sodium citrate tribasic dihydrate, 800uM EB47
Resolution 3.00 Å R-free 0.248
8SWZ PARP4 ART domain bound to EB47 Deposited 2023-05-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 242–282（41 aa）
Chain B 365–573（209 aa）
Not recorded GOL GLYCEROL × 1 UHB 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；20% PEG3350, 0.2M sodium citrate tribasic dihydrate, 800uM EB47
Resolution 3.00 Å R-free 0.248
8SWZ PARP4 ART domain bound to EB47 Deposited 2023-05-19 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 242–282（41 aa）
Chain C 365–573（209 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；20% PEG3350, 0.2M sodium citrate tribasic dihydrate, 800uM EB47
Resolution 3.00 Å R-free 0.248
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain F 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain G 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX1 PARP4 catalytic domain Deposited 2023-05-19 Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain H 242–573（332 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350 and 0.1 M Bis-Tris pH 6.5
Resolution 4.20 Å R-free 0.331
8SX2 PARP4 catalytic domain bound to EB47 Deposited 2023-05-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 242–573（332 aa）
Not recorded UHB 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350, 0.1 M Bis-Tris pH 6.5, 0.2 M MgCl2, and 600 uM EB47
Resolution 2.95 Å R-free 0.262
8SX2 PARP4 catalytic domain bound to EB47 Deposited 2023-05-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 242–573（332 aa）
Not recorded UHB 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；23% PEG3350, 0.1 M Bis-Tris pH 6.5, 0.2 M MgCl2, and 600 uM EB47
Resolution 2.95 Å R-free 0.262
9BW6 Human Vault Cage in complex with PARP4 Deposited 2024-05-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 156 PDB declaration: 156-meric（156） Consistent with protein count
Chain B 1–1724（1724 aa）
Chain D 1–1724（1724 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8；50 mM HEPES, 5 mM MgCl2, 5 mM CaCl2, 0.25 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out under standard conditions
Resolution 2.90 Å
9BW6 Human Vault Cage in complex with PARP4 Deposited 2024-05-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–1724（1724 aa）
Chain D 1–1724（1724 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8；50 mM HEPES, 5 mM MgCl2, 5 mM CaCl2, 0.25 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out under standard conditions
Resolution 2.90 Å
9BW7 Human Vault Cage in complex with PARP4 and NAD+ Deposited 2024-05-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 156 PDB declaration: 156-meric（156） Consistent with protein count
Chain B 1–1724（1724 aa）
Chain D 1–1724（1724 aa）
Not recorded NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 78 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；50 mM HEPES, 5 mM MgCl2, 5 mM CaCl2, 0.25 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out under standard conditions
Resolution 2.90 Å
9BW7 Human Vault Cage in complex with PARP4 and NAD+ Deposited 2024-05-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–1724（1724 aa）
Chain D 1–1724（1724 aa）
Not recorded NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；50 mM HEPES, 5 mM MgCl2, 5 mM CaCl2, 0.25 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out under standard conditions
Resolution 2.90 Å
9DEV PARP4 BRCT domain Deposited 2024-08-29 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–100（100 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；2M ammonium sulfate, 0.15M Citric Acid pH3.5
Resolution 1.75 Å R-free 0.188
9DFO PARP4 BRCT domain K31Q mutant Deposited 2024-08-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–100（100 aa）
Mutation：K31Q SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；31% PEG3350, 0.2M ammonium sulfate and 0.1M sodium acetate pH 4.6
Resolution 1.90 Å R-free 0.208
9DFP PARP4 BRCT domain K23/24Q mutant Deposited 2024-08-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–100（100 aa）
Mutation：K23Q,K24Q SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；27% PEG3350, 0.2M ammonium sulfate and 0.1M sodium acetate pH 4.6
Resolution 1.92 Å R-free 0.219
9DFQ PARP4 BRCT domain F39Q mutant Deposited 2024-08-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–100（100 aa）
Mutation：F39Q SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；2 M ammonium sulfate and 0.1 M sodium acetate pH 4.6
Resolution 2.10 Å R-free 0.230
9DFR PARP4 BRCT domain F39A mutant Deposited 2024-08-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–100（100 aa）
Mutation：F39A SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；27% PEG3350, 0.2M ammonium sulfate and 0.1M sodium acetate pH 4.6
Resolution 1.90 Å R-free 0.218

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.