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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9Y294 New Search
18PDB entries
45Biological assembly
61chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1TEY NMR structure of human histone chaperone, ASF1A Deposited 2004-05-26 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–156（156 aa） Fragment：N-TERMINAL DOMAIN (residues 1-156)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.4；298 K；Ionic strength (raw mmCIF value) 20 mM；Pressure ambient
NMR sample composition 1mM Asf1A U-15N,13C; 20mM tris-D11; 1mM EDTA; 0.1mM DSS; 0.1 mM NaN3; 90% H2O, 10% D2O | 90% H2O/10% D2O
Resolution not provided
2I32 Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly Deposited 2006-08-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–157（157 aa） Fragment：Residues 1-157
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；298 K；CRYSTALS OF THE HUMAN ASF1AN-HIRA(425-472) COMPLEX WERE GROWN BY HANGING DROP VAPOR DIFFUSION AT ROOM TEMPERATURE AND WERE OBTAINED BY MIXING 2 UL OF A 0.5 MM PROTEIN COMPLEX SOLUTION (IN 20 MM HEPES PH 7.0, 150 MM NACL AND 5 MM BETA-ME) WITH 2 UL OF RESERVOIR SOLUTION CONTAINING 1.44 M NAH2PO4 AND 0.16 M K2HPO4 AT PH 5.6, AND EQUILIBRATING OVER 1.0 ML OF RESERVOIR SOLUTION. CRYSTALS WERE FULLY GROWN WITHIN TWO WEEKS TO A TYPICAL SIZE OF 0.3MMX0.3MMX0.2MM, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298.0K
Resolution 2.70 Å R-free 0.269
2I32 Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly Deposited 2006-08-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–157（157 aa） Fragment：Residues 1-157
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；298 K；CRYSTALS OF THE HUMAN ASF1AN-HIRA(425-472) COMPLEX WERE GROWN BY HANGING DROP VAPOR DIFFUSION AT ROOM TEMPERATURE AND WERE OBTAINED BY MIXING 2 UL OF A 0.5 MM PROTEIN COMPLEX SOLUTION (IN 20 MM HEPES PH 7.0, 150 MM NACL AND 5 MM BETA-ME) WITH 2 UL OF RESERVOIR SOLUTION CONTAINING 1.44 M NAH2PO4 AND 0.16 M K2HPO4 AT PH 5.6, AND EQUILIBRATING OVER 1.0 ML OF RESERVOIR SOLUTION. CRYSTALS WERE FULLY GROWN WITHIN TWO WEEKS TO A TYPICAL SIZE OF 0.3MMX0.3MMX0.2MM, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298.0K
Resolution 2.70 Å R-free 0.269
3AAD Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction Deposited 2009-11-16 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 1–155（155 aa） Fragment：Residues 1-155
Chain D 1–155（155 aa） Fragment：Residues 1-155
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.65；293 K；0.1M MES, 1.1M AMMONIUM SULFATE, 0.25M LITHIUM SULFATE, pH 5.65, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.30 Å R-free 0.293
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain I 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 3 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 4 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain M 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 5 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain Q 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
5C3I Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Deposited 2015-06-17 Assembly 6 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain U 1–175（175 aa） Fragment：UNP residues 1-175
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；289 K；20% PEG 3350, 2% Tacsimate,0.1 M Tris-HCl pH 8.0
Resolution 3.50 Å R-free 0.253
6F0F Crystal structure ASF1-ip2_s Deposited 2017-11-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.5；298 K；Tris-HCl 0.1M pH7.5, PEG8000 5%
Resolution 2.00 Å R-free 0.227
6F0G Crystal structure ASF1-ip3 Deposited 2017-11-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Citrate 0.1M pH 2.5, LiSO4 0.25M, PEG8000 7%
Resolution 2.30 Å R-free 0.267
6F0G Crystal structure ASF1-ip3 Deposited 2017-11-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–156（156 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Citrate 0.1M pH 2.5, LiSO4 0.25M, PEG8000 7%
Resolution 2.30 Å R-free 0.267
6F0H Crystal structure ASF1-ip4 Deposited 2017-11-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 1–156（156 aa）
Chain C 1–156（156 aa）
Not recorded SO4 SULFATE ION × 12 GOL GLYCEROL × 6 CIT CITRIC ACID × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Citrate 0.1M pH 2.5, LiSO4 0.5M, PEG8000 10%
Resolution 1.98 Å R-free 0.242
6ZUF Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone Deposited 2020-07-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded GOL GLYCEROL × 3 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.2；293 K；100 mM Sodium Citrate pH4.2, 300 mM LiSO4, 26% PEG3350
Resolution 1.80 Å R-free 0.210
6ZUF Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone Deposited 2020-07-22 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–156（156 aa）
Not recorded GOL GLYCEROL × 6 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.2；293 K；100 mM Sodium Citrate pH4.2, 300 mM LiSO4, 26% PEG3350
Resolution 1.80 Å R-free 0.210
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain F 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LNY Apo structure of the Histone chaperone ASF1A residues 1-155 Deposited 2021-02-08 Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain G 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；1 ml reservoir of 22% PEG3350 and 6% of Tascimate pH6.0
Resolution 2.10 Å R-free 0.242
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain D 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 5 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain E 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 6 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain F 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 7 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain G 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7LO0 Structure of human ASF1a in complex with a TLK2 peptide Deposited 2021-02-08 Assembly 8 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain H 1–155（155 aa） Fragment：Residues 1-155
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；18% PEG3350, 0.2 M of trisodium citrate, pH 5.6 and 2% Octyl-D-glucose
Resolution 2.71 Å R-free 0.226
7V6Q Crystal structure of sNASP-ASF1A-H3.1-H4 complex Deposited 2021-08-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded GOL GLYCEROL × 4 1PE PENTAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；18% (v/v) Tacsimate, pH 5.0 11% (v/v) PEG2000MME
Resolution 3.00 Å R-free 0.203
7V6Q Crystal structure of sNASP-ASF1A-H3.1-H4 complex Deposited 2021-08-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 1–156（156 aa）
Not recorded GOL GLYCEROL × 2 1PE PENTAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；18% (v/v) Tacsimate, pH 5.0 11% (v/v) PEG2000MME
Resolution 3.00 Å R-free 0.203
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded GOL GLYCEROL × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–156（156 aa）
Not recorded GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 1–156（156 aa）
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 1–156（156 aa）
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 1–156（156 aa）
Not recorded GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8BV1 Peptide inhibitor P4 in complex with ASF1 histone chaperone Deposited 2022-12-01 Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 1–156（156 aa）
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；290.15 K；0.1 M Tris pH 8.5 30% (w/v) PEG 400
Resolution 2.83 Å R-free 0.221
8CJ1 Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone Deposited 2023-02-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 1–156（156 aa）
Chain B 1–156（156 aa）
Chain C 1–156（156 aa）
Chain D 1–156（156 aa）
Chain E 1–156（156 aa）
Chain F 1–156（156 aa）
Chain G 1–156（156 aa）
Chain H 1–156（156 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；290.15 K；0.1 M MES pH 6.5 40% (w/v) PEG 200
Resolution 2.56 Å R-free 0.280
8CJ2 Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone Deposited 2023-02-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 1–156（156 aa）
Chain B 1–156（156 aa）
Chain C 1–156（156 aa）
Chain D 1–156（156 aa）
Not recorded GOL GLYCEROL × 14 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；290.15 K；0.17 M ammonium sulfate 0.085 M NaOAc pH 4.6 25.5% PEG 2000 MME 15% (v/v) glycerol
Resolution 2.13 Å R-free 0.215
8CJ3 Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone Deposited 2023-02-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–156（156 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；290.15 K；0.2 M potassium fluoride 20% (w/v) PEG 3350
Resolution 3.00 Å R-free 0.217
8Z50 Crystal structure of the ASF1-H3T-H4 complex Deposited 2024-04-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–173（173 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；1.0 M Lithium chloride, 0.1 M MES pH 6.0, 10% PEG 6000
Resolution 2.80 Å R-free 0.255
9CVC CDAN1 dimer with three ASF1A Deposited 2024-07-29 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain C 1–204（204 aa）
Chain D 1–204（204 aa）
Chain E 1–204（204 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
9IMZ CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate histone supply Deposited 2024-07-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain C 1–172（172 aa）
Chain D 1–172（172 aa）
Chain E 1–172（172 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.75 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.