← Back to search
11tk

Structure of human CCR4 in complex with AZD2098

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

C-C chemokine receptor type 4,Soluble cytochrome b562

Homo sapiens

UniProt P0ABE7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 3 Anti-BRIL Fab heavy chain × 1 Anti-BRIL Fab light chain × 1 2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1apc 1m6t 1qpu 1qq3 256b 256b 2bc5 2bc5 2bc5 2bc5 3fop 3fop

78 assemblies; showing the first 12

Homodimer
1lm3 2bc5 2bc5 3de8 3de8 3hnk 3hnl 3l1m 3tol 3tol 3tom 3tom

35 assemblies; showing the first 12

Homotetramer
2bc5 2bc5 2bc5 2bc5 2qla 3c62 3c63 3de8 3hni 3hni 3hnj 3hnl

36 assemblies; showing the first 12

Other homooligomers
3de9 3foo 3foo 3foo 3foo 3fop 3m15 3m4b 6dhz 6ot4 6ot7 6ot8

39 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
10kt 11td 11tf 11th 11tk 11tl 22em 24xy 24xz 25ik 25il 28vj

635 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name C562_ECOLX
Isoform —
PDB entities 1
Chains and sequence ranges Author chain R； PDBConstruct 237–341； UniProt 23–127

C-C chemokine receptor type 4,Soluble cytochrome b562

Homo sapiens

UniProt P51679

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 3 Anti-BRIL Fab heavy chain × 1 Anti-BRIL Fab light chain × 1 2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzene-1-sulfonamide × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
11td 11tf 11th 11tk 11tl 9ull 9ull 9ulm 9ulm

9 assemblies

View Construct and Data Evidence
UniProt name CCR4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain R； PDBConstruct 1–231； UniProt 1–231 Author chain R； PDBConstruct 352–475； UniProt 237–360

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id11tk
Deposition date deposition_date2026-03-12
Structure title titleStructure of human CCR4 in complex with AZD2098
Keywords keywordsG protein coupled receptor, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

11tk__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

11tk__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

11tk__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）37.16 Å
Rg (electron density)37.61 Å
Total Rg37.78 Å
Atom count4933
Residues620
Excluded volume88864 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 11tk__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▶

7. Citations (1)