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1bbr

THE STRUCTURE OF RESIDUES 7-16 OF THE A ALPHA CHAIN OF HUMAN FIBRINOGEN BOUND TO BOVINE THROMBIN AT 2.3 ANGSTROMS RESOLUTION

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

EPSILON-THROMBIN

Bos taurus

UniProt P00735

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR × 1 （P02671） water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR × 1 （P02671） water × 3 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR × 1 （P02671） water × 3 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 6 FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR × 2 （P02671） water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mkw 1mkx 1mkx 2pf1 2pf2 2spt

6 assemblies

Homodimer
1etr 1ets 1ett 1mkw 1mkx 1mkx 1uvt 1uvu 3pmb 3pmb

10 assemblies

Homotetramer
1mkx

1 assemblies

Other homooligomers
1mkx

1 assemblies

Heteromeric or nucleic-acid complex
1a0h 1avg 1bbr 1bbr 1bbr 1bbr 1hrt 1id5 1nl1 1nl2 1tbq 1tbq

38 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name THRB_BOVIN
Isoform —
PDB entities 1, 2, 3, 5
Chains and sequence ranges Author chain J； PDBConstruct 1–49； UniProt 318–366 Author chain L； PDBConstruct 1–49； UniProt 318–366 Author chain M； PDBConstruct 1–49； UniProt 318–366 Author chain H； PDBConstruct 1–149； UniProt 367–516 Author chain E； PDBConstruct 1–109； UniProt 517–625 Author chain K； PDBConstruct 1–259； UniProt 367–625 Author chain N； PDBConstruct 1–259； UniProt 367–625

FIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR

Homo sapiens

UniProt P02671

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 EPSILON-THROMBIN × 1 （P00735） EPSILON-THROMBIN × 1 （P00735） EPSILON-THROMBIN × 1 （P00735） water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 EPSILON-THROMBIN × 1 （P00735） EPSILON-THROMBIN × 1 （P00735） water × 3 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 EPSILON-THROMBIN × 1 （P00735） EPSILON-THROMBIN × 1 （P00735） water × 3 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 6 EPSILON-THROMBIN × 2 （P00735） EPSILON-THROMBIN × 2 （P00735） water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1bbr 1bbr 1bbr 1bbr 1fza 1fzb 1fzc 1fzd 1fzd 1fze 1fze 1fze

70 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name FIBA_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain F； PDBConstruct 2–11； UniProt 26–35 Author chain G； PDBConstruct 2–11； UniProt 26–35 Author chain I； PDBConstruct 2–11； UniProt 26–35

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1bbr
Deposition date deposition_date1992-04-27
Structure title titleTHE STRUCTURE OF RESIDUES 7-16 OF THE A ALPHA CHAIN OF HUMAN FIBRINOGEN BOUND TO BOVINE THROMBIN AT 2.3 ANGSTROMS RESOLUTION
Keywords keywordsSERINE PROTEASE; SERINE PROTEASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1bbr__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1bbr__assembly_3__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1bbr__assembly_3__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.34 Å
Rg (electron density)18.18 Å
Total Rg19.23 Å
Atom count2459
Residues305
Excluded volume43785 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1bbr__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1bbr__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1bbr__assembly_3__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1bbr__assembly_4__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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6. Fold Classification (SCOP + CATH) 9 domains

SCOP 2.08 (3 domains)

Domain ID domain_idd1bbr.1
Class classb — All beta proteins
Fold Fold foldb.47 — Trypsin-like serine proteases
Superfamily Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
Family Family familyb.47.1.2 — Eukaryotic proteases
Domain ID domain_idd1bbr.2
Class classb — All beta proteins
Fold Fold foldb.47 — Trypsin-like serine proteases
Superfamily Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
Family Family familyb.47.1.2 — Eukaryotic proteases
Domain ID domain_idd1bbr.3
Class classb — All beta proteins
Fold Fold foldb.47 — Trypsin-like serine proteases
Superfamily Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
Family Family familyb.47.1.2 — Eukaryotic proteases

CATH v4.4 (6 domains)

Domain ID domain_id1bbrE00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1bbrH00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1bbrK01
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1bbrK02
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1bbrN01
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1bbrN02
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
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7. Citations (1)