SAXSdb — 1blx

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1. Structure Basics

entry_id	1blx
deposition_date	1998-07-21
title	P19INK4D/CDK6 COMPLEX
keywords	;INHIBITOR PROTEIN, CYCLIN-DEPENDENT KINASE, CELL CYCLE CONTROL, ALPHA/BETA, COMPLEX (INHIBITOR PROTEIN-KINASE), COMPLEX (INHIBITOR PROTEIN-KINASE) complex ;; COMPLEX (INHIBITOR PROTEIN/KINASE)
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	24.86 Å
rg_electron	23.79 Å
i0	43270500.00
molecular_weight	50650.0 kDa
excluded_volume	63420 Å³
envelope_volume	78745 Å³
shell_volume	27750 Å³
envelope_diameter	87.9 Å
shell_rg	30.82 Å
envelope_rg	23.84 Å
shape_rg	23.78 Å
total_rg	24.62 Å
total_atoms	3564
n_residues	465
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	84.3 Å
rg_real	24.77 Å
rg_real_error	0.75 Å
i0_real	4.3270e+07
i0_real_error	7.2060e+05
rg_reciprocal	24.79 Å
i0_reciprocal	43270000.0000
total_estimate	0.7988
solution_quality	GOOD a GOOD solution
n_peaks	3
r_peak_primary	32.1 Å
skewness	0.261
kurtosis	-0.312
angular_range	— – 0.3200 Å⁻¹
current_alpha	0.0000
highest_alpha	12210000.0000
n_real_points	64
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.804; Stabil: 0.994; Sysdev: 1.000; Positv: 1.000; Valcen: 0.986; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	CYCLIN-DEPENDENT KINASE 6
formula_weight	36987.3 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	3858

MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Spodoptera frugiperda

Entity 2 polymer

description	P19INK4D
formula_weight	17832.4 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

MLLEEVCVGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDILQGHMMIPM

Source

organism	Mus musculus
common_name	house mouse
ncbi_taxonomy_id	10090
host_organism	Escherichia coli BL21(DE3)

Entity 3 non-polymer

description	CALCIUM ION
formula_weight	40.1 kDa
src_method	syn
entity_count	1

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	294

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6. Citations (2)

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length_a	74.210 Å
length_b	76.410 Å
length_c	93.800 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	1.900 Å
resolution_low	18.540 Å
r_factor	—
r_work	0.2000
r_free	0.2530

fit	/app/data/saxs_computation/bl/1blx/1blx.fit
pddf	/app/data/pr_computation/bl/1blx/1blx.pr.out
profile	/app/data/saxs_computation/bl/1blx/1blx.dat

P19INK4D/CDK6 COMPLEX

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (4)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 water

6. Citations (2)

7. Files & Curves (10)

Files (7)

Curves (3)