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1c1o

RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES

Method: X-RAY DIFFRACTION Dmax: 56.7 Å Quality: GOOD

SAXS Profile

SAXS profile for 1c1o

P(r) Distribution

P(r) distribution for 1c1o

1. Structure Basics

entry_id1c1o
deposition_date1999-07-21
titleRECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
keywords;ZN(II)-MEDIATED SERINE PROTEASE INHIBITORS, PH DEPENDENCE, ZN(II) AFFINITY STUCTURE-BASED DRUG DESIGN, SERINE PROTEASE SERINE PROTEASE/INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX ;; HYDROLASE/HYDROLASE INHIBITOR
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier17.23
rg_electron16.10
i010964500.00
molecular_weight23568.0 kDa
excluded_volume29026 ų
envelope_volume31964 ų
shell_volume16428 ų
envelope_diameter54.0
shell_rg22.44
envelope_rg16.31
shape_rg16.08
total_rg17.11
total_atoms3234
n_residues223
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax56.7
rg_real17.11
rg_real_error0.39
i0_real1.0960e+07
i0_real_error1.3270e+05
rg_reciprocal17.12
i0_reciprocal10960000.0000
total_estimate0.8015
solution_quality GOOD a GOOD solution
n_peaks3
r_peak_primary22.4
skewness0.125
kurtosis-0.446
angular_range— – 0.4600 −1
current_alpha0.0000
highest_alpha3006000.0000
n_real_points77
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.806; Stabil: 0.999; Sysdev: 1.000; Positv: 1.000; Valcen: 0.999; Smooth: 0.000

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)