1cwb
;THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY ;
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1cwb |
| deposition_date | 1995-09-06 |
| title | ;THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY ; |
| keywords | ISOMERASE-IMMUNOSUPPRESSANT COMPLEX, CYCLOPHILIN-CYCLOSPORIN COMPLEX, CYCLOSPORIN A, IMMUNOSUPPRESSANT, CYCLOPHILIN; ISOMERASE/IMMUNOSUPPRESSANT |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 15.75 Å |
| rg_electron | 14.62 Å |
| i0 | 6702050.00 |
| molecular_weight | 19239.0 kDa |
| excluded_volume | 24258 ų |
| envelope_volume | 26164 ų |
| shell_volume | 14720 ų |
| envelope_diameter | 51.6 Å |
| shell_rg | 21.00 Å |
| envelope_rg | 14.91 Å |
| shape_rg | 14.58 Å |
| total_rg | 15.90 Å |
| total_atoms | 1352 |
| n_residues | 167 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 51.0 Å |
| rg_real | 15.61 Å |
| rg_real_error | 0.25 Å |
| i0_real | 6.7020e+06 |
| i0_real_error | 6.1500e+04 |
| rg_reciprocal | 15.63 Å |
| i0_reciprocal | 6702000.0000 |
| total_estimate | 0.7962 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 21.3 Å |
| skewness | 0.065 |
| kurtosis | -0.364 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 2659000.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.784; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.993; Smooth: 0.000 |