1cwk
HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1cwk |
| deposition_date | 1998-05-26 |
| title | HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN |
| keywords | ISOMERASE-IMMUNOSUPPRESSANT COMPLEX, CYCLOPHILIN-CYCLOSPORIN COMPLEX, CYCLOSPORIN D, IMMUNOSUPPRESSANT, CYCLOPHILIN; ISOMERASE/IMMUNOSUPPRESSANT |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 15.72 Å |
| rg_electron | 14.58 Å |
| i0 | 6747760.00 |
| molecular_weight | 19286.0 kDa |
| excluded_volume | 24310 ų |
| envelope_volume | 26021 ų |
| shell_volume | 14680 ų |
| envelope_diameter | 51.2 Å |
| shell_rg | 20.94 Å |
| envelope_rg | 14.85 Å |
| shape_rg | 14.54 Å |
| total_rg | 15.83 Å |
| total_atoms | 1354 |
| n_residues | 168 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 50.2 Å |
| rg_real | 15.59 Å |
| rg_real_error | 0.21 Å |
| i0_real | 6.7480e+06 |
| i0_real_error | 6.8480e+04 |
| rg_reciprocal | 15.60 Å |
| i0_reciprocal | 6748000.0000 |
| total_estimate | 0.8785 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 1 |
| r_peak_primary | 49.0 Å |
| skewness | 0.050 |
| kurtosis | -0.391 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 2701000.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.810; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.989; Smooth: 0.995 |