Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | water × 1 | Consistent with protein count |
| UniProt name | GBP1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–592； UniProt 1–592 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1dg3 |
| Deposition date deposition_date | 1999-11-23 |
| Structure title title | STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM |
| Keywords keywords | GBP, GTP HYDROLYSIS, GDP, GMP, INTERFERON INDUCED, DYNAMIN RELATED, LARGE GTPASE FAMILY, SIGNALING PROTEIN; SIGNALING PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 37.77 Å |
| Rg (electron density) | 38.95 Å |
| Total Rg | 38.79 Å |
| Atom count | 4357 |
| Residues | 540 |
| Excluded volume | 77957 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1dg3a1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.114 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
| Superfamily Superfamily superfamily | a.114.1 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
| Family Family family | a.114.1.1 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
| Domain ID domain_id | d1dg3a2 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| Superfamily Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| Family Family family | c.37.1.8 — G proteins |
| Domain ID domain_id | 1dg3A01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1000 — Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 |
| Homologous superfamily homologous superfamily | 10 — Guanylate-binding protein, C-terminal domain |
| Domain ID domain_id | 1dg3A02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |