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1f5q

CRYSTAL STRUCTURE OF MURINE GAMMA HERPESVIRUS CYCLIN COMPLEXED TO HUMAN CYCLIN DEPENDENT KINASE 2

Method: X-RAY DIFFRACTION D_max: 135.3 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1f5q
deposition_date	2000-06-15
title	CRYSTAL STRUCTURE OF MURINE GAMMA HERPESVIRUS CYCLIN COMPLEXED TO HUMAN CYCLIN DEPENDENT KINASE 2
keywords	herpesviral cyclin, cyclin dependent kinase. protein-protein complex, TRANSFERASE; TRANSFERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	39.80 Å
rg_electron	40.08 Å
i0	211727000.00
molecular_weight	121620.0 kDa
excluded_volume	153510 Å³
envelope_volume	202280 Å³
shell_volume	43790 Å³
envelope_diameter	135.9 Å
shell_rg	43.34 Å
envelope_rg	39.71 Å
shape_rg	40.12 Å
total_rg	40.13 Å
total_atoms	8551
n_residues	1079
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	135.3 Å
rg_real	40.10 Å
rg_real_error	1.20 Å
i0_real	2.1170e+08
i0_real_error	3.5180e+06
rg_reciprocal	39.93 Å
i0_reciprocal	211700000.0000
total_estimate	0.8573
solution_quality	GOOD a GOOD solution
n_peaks	1
r_peak_primary	37.2 Å
skewness	0.397
kurtosis	-0.604
angular_range	— – 0.2000 Å⁻¹
current_alpha	0.0000
highest_alpha	44370000.0000
n_real_points	41
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.823; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.786; Smooth: 0.885

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	CYCLIN DEPENDENT KINASE 2
formula_weight	33976.5 kDa
ec_number	2.7.1.-
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,C
atom_count	8723

MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Spodoptera frugiperda

Entity 2 polymer

description	GAMMA HERPESVIRUS CYCLIN
formula_weight	29067.6 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	B,D

MASQEFQGFLDSSLLNEEDCRQMIYRSEREHDARMVGVNVDQHFTSQYRKVLTTWMFCVCKDLRQDNNVFPLAVALLDELFLSTRIDRENYQSTAAVALHIAGKVRAYMPIKATQLAYLCGGATTADKLLTLEVKSLDTLSWVADRCLSTDLICYILHIMHAPREDYLNIYNLCRPKIFCALCDGRSAMKRPVLITLACMHLTMNQKYDYYENRIDGVCKSLYITKEELHQCCDLVDIAIVSFDENYFKINA

Source

organism	Murid herpesvirus 4
common_name	Murine herpesvirus 68
ncbi_taxonomy_id	33708
host_organism	Escherichia coli

Entity 3 non-polymer

description	CHLORIDE ION
formula_weight	35.5 kDa
src_method	syn
entity_count	1

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	166

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6. Citations (1)

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length_a	87.590 Å
length_b	73.450 Å
length_c	107.670 Å
angle_alpha	90.00 °
angle_beta	102.18 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 1 21 1
int_tables_number	4
crystal_system	—

resolution	2.500 Å
resolution_low	30.000 Å
r_factor	0.2340
r_work	0.2340
r_free	0.2780

fit	/app/data/saxs_computation/f5/1f5q/1f5q.fit
pddf	/app/data/pr_computation/f5/1f5q/1f5q.pr.out
profile	/app/data/saxs_computation/f5/1f5q/1f5q.dat

CRYSTAL STRUCTURE OF MURINE GAMMA HERPESVIRUS CYCLIN COMPLEXED TO HUMAN CYCLIN DEPENDENT KINASE 2

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (4)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)