1fc2

;Crystallographic Refinement and Atomic Models of a Human FC Fragment and its Complex with Fragment B of Protein A from Staphylococcus Aureus at 2.9-and 2.8-Angstroms Resolution ;

Method: X-RAY DIFFRACTION Dmax: 76.0 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1fc2

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1fc2
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1fc2
沉积日期 deposition_date1981-05-21
结构标题 title;Crystallographic Refinement and Atomic Models of a Human FC Fragment and its Complex with Fragment B of Protein A from Staphylococcus Aureus at 2.9-and 2.8-Angstroms Resolution ;
关键词 keywordsIMMUNOGLOBULIN; IMMUNOGLOBULIN
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier23.00
回转半径 Rg (电子) rg_electron21.96
零角强度 I(0) i016429300.00
分子量 molecular_weight30202.0 kDa
排除体积 excluded_volume37673 ų
包络体积 envelope_volume47758 ų
水化壳体积 shell_volume19021 ų
包络直径 envelope_diameter78.4
壳层 Rg shell_rg27.80
包络 Rg envelope_rg22.21
形状 Rg shape_rg21.95
总 Rg total_rg22.82
总原子数 total_atoms2125
残基数 n_residues251
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax76.0
Rg (实空间) rg_real23.01
Rg 误差 (实空间) rg_real_error0.43
I(0) (实空间) i0_real1.6430e+07
I(0) 误差 (实空间) i0_real_error2.1180e+05
Rg (倒空间) rg_reciprocal23.01
I(0) (倒空间) i0_reciprocal16430000.0000
解质量估计 total_estimate0.8970
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary23.4
偏度 Skewness skewness0.297
峰度 Kurtosis kurtosis-0.507
角度范围 angular_range— – 0.3450 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha4091000.0000
实空间数据点数 n_real_points66
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.906; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.941; Smooth: 0.998

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

结构域编号 domain_idd1fc2c_
类 Class classa — All alpha proteins
折叠类型 Fold folda.8 — immunoglobulin/albumin-binding domain-like
超家族 Superfamily superfamilya.8.1 — Bacterial immunoglobulin/albumin-binding domains
家族 Family familya.8.1.1 — Immunoglobulin-binding protein A modules
结构域编号 domain_idd1fc2d1
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)
结构域编号 domain_idd1fc2d2
类 Class classb — All beta proteins
折叠类型 Fold foldb.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamilyb.1.1 — Immunoglobulin
家族 Family familyb.1.1.2 — C1 set domains (antibody constant domain-like)

CATH v4.4 (3 domains)

结构域编号 domain_id1fc2C00
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily420 — Immunoglobulin FC, subunit C
结构域编号 domain_id1fc2D01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id1fc2D02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins

7. 引用文献 (2)

8. 文件与曲线 (10)