1hcq

;THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS ;

Method: X-RAY DIFFRACTION Dmax: 122.8 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1hcq

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1hcq
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1hcq
沉积日期 deposition_date1995-01-04
结构标题 title;THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS ;
关键词 keywordsPROTEIN-DNA COMPLEX, COMPLEXED WITH DRUG, TRANSCRIPTION-DNA COMPLEX; TRANSCRIPTION/DNA
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier34.44
回转半径 Rg (电子) rg_electron34.92
零角强度 I(0) i084182600.00
分子量 molecular_weight54933.0 kDa
排除体积 excluded_volume60668 ų
包络体积 envelope_volume88836 ų
水化壳体积 shell_volume23320 ų
包络直径 envelope_diameter118.8
壳层 Rg shell_rg36.88
包络 Rg envelope_rg34.48
形状 Rg shape_rg34.95
总 Rg total_rg34.96
总原子数 total_atoms3706
残基数 n_residues362
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax122.8
Rg (实空间) rg_real34.90
Rg 误差 (实空间) rg_real_error1.53
I(0) (实空间) i0_real8.4180e+07
I(0) 误差 (实空间) i0_real_error1.4910e+06
Rg (倒空间) rg_reciprocal34.62
I(0) (倒空间) i0_reciprocal84160000.0000
解质量估计 total_estimate0.7613
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary24.0
偏度 Skewness skewness0.536
峰度 Kurtosis kurtosis-0.507
角度范围 angular_range— – 0.2300 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha2816000.0000
实空间数据点数 n_real_points47
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.563; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.344; Smooth: 0.860

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (5)

6. 折叠分类 (SCOP + CATH) 8 domains

SCOP 2.08 (4 domains)

结构域编号 domain_idd1hcqa_
类 Class classg — Small proteins
折叠类型 Fold foldg.39 — Glucocorticoid receptor-like (DNA-binding domain)
超家族 Superfamily superfamilyg.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
家族 Family familyg.39.1.2 — Nuclear receptor
结构域编号 domain_idd1hcqb_
类 Class classg — Small proteins
折叠类型 Fold foldg.39 — Glucocorticoid receptor-like (DNA-binding domain)
超家族 Superfamily superfamilyg.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
家族 Family familyg.39.1.2 — Nuclear receptor
结构域编号 domain_idd1hcqe_
类 Class classg — Small proteins
折叠类型 Fold foldg.39 — Glucocorticoid receptor-like (DNA-binding domain)
超家族 Superfamily superfamilyg.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
家族 Family familyg.39.1.2 — Nuclear receptor
结构域编号 domain_idd1hcqf_
类 Class classg — Small proteins
折叠类型 Fold foldg.39 — Glucocorticoid receptor-like (DNA-binding domain)
超家族 Superfamily superfamilyg.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
家族 Family familyg.39.1.2 — Nuclear receptor

CATH v4.4 (4 domains)

结构域编号 domain_id1hcqA00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology50 — Erythroid Transcription Factor GATA-1; Chain A
同源超家族 H-superfamily homologous superfamily10 — Erythroid Transcription Factor GATA-1, subunit A
结构域编号 domain_id1hcqB00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology50 — Erythroid Transcription Factor GATA-1; Chain A
同源超家族 H-superfamily homologous superfamily10 — Erythroid Transcription Factor GATA-1, subunit A
结构域编号 domain_id1hcqE00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology50 — Erythroid Transcription Factor GATA-1; Chain A
同源超家族 H-superfamily homologous superfamily10 — Erythroid Transcription Factor GATA-1, subunit A
结构域编号 domain_id1hcqF00
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology50 — Erythroid Transcription Factor GATA-1; Chain A
同源超家族 H-superfamily homologous superfamily10 — Erythroid Transcription Factor GATA-1, subunit A

7. 引用文献 (2)

8. 文件与曲线 (10)