1kp8

Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

groEL protein

Escherichia coli

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 14	SULFATE ION × 22 MAGNESIUM ION × 14 POTASSIUM ION × 16 PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 14 water × 14	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	CH60_ECOLI
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–547； UniProt 1–547 作者链 B； PDB构建体 1–547； UniProt 1–547 作者链 C； PDB构建体 1–547； UniProt 1–547 作者链 D； PDB构建体 1–547； UniProt 1–547 作者链 E； PDB构建体 1–547； UniProt 1–547 作者链 F； PDB构建体 1–547； UniProt 1–547 作者链 G； PDB构建体 1–547； UniProt 1–547 作者链 H； PDB构建体 1–547； UniProt 1–547 作者链 I； PDB构建体 1–547； UniProt 1–547 作者链 J； PDB构建体 1–547； UniProt 1–547 作者链 K； PDB构建体 1–547； UniProt 1–547 作者链 L； PDB构建体 1–547； UniProt 1–547 作者链 M； PDB构建体 1–547； UniProt 1–547 作者链 N； PDB构建体 1–547； UniProt 1–547

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1kp8
沉积日期 deposition_date	2001-12-30
结构标题 title	Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution
关键词 keywords	chaperonin, GroEL, assisted protein folding, CHAPERONE; CHAPERONE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1kp8__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1kp8__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

1kp8__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	64.75 Å
Rg（电子密度）	63.73 Å
总 Rg	63.75 Å
原子数	54544
残基数	7350
排除体积	976220 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`1kp8__assembly_1__model_1`	tetradecameric （14）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

描述 description	groEL protein
分子量 formula_weight	57130.4 kDa
突变 mutation	R13G, A126V
来源方法 src_method	man
拷贝数 entity_count	14

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N
原子数 atom_count	57085

AAKDVKFGNDAGVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTVAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNADQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM

来源 Source

来源生物 organism	Escherichia coli
NCBI 分类编号 ncbi_taxonomy_id	562
宿主生物 host_organism	Escherichia coli

实体 2 Entity 2 non-polymer

描述 description	SULFATE ION
分子量 formula_weight	96.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	22

实体 3 Entity 3 non-polymer

描述 description	MAGNESIUM ION
分子量 formula_weight	24.3 kDa
来源方法 src_method	syn
拷贝数 entity_count	14

实体 4 Entity 4 non-polymer

描述 description	POTASSIUM ION
分子量 formula_weight	39.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	16

实体 5 Entity 5 non-polymer

描述 description	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
分子量 formula_weight	523.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	14

实体 6 Entity 6 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	2541

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6. 折叠分类 (SCOP + CATH) 84 domains

SCOP 2.08 (42 domains)

结构域编号 domain_id	d1kp8a1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8a2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8a3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8b1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8b2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8b3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8c1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8c2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8c3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8d1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8d2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8d3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8e1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8e2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8e3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8f1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8f2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8f3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8g1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8g2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8g3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8h1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8h2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8h3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8i1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8i2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8i3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8j1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8j2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8j3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8k1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8k2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8k3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8l1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8l2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8l3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8m1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8m2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8m3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

结构域编号 domain_id	d1kp8n1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.129 — GroEL equatorial domain-like
超家族 Superfamily superfamily	a.129.1 — GroEL equatorial domain-like
家族 Family family	a.129.1.1 — GroEL chaperone, ATPase domain

结构域编号 domain_id	d1kp8n2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.8 — The 'swivelling' beta/beta/alpha domain
超家族 Superfamily superfamily	c.8.5 — GroEL apical domain-like
家族 Family family	c.8.5.1 — GroEL-like chaperone, apical domain

结构域编号 domain_id	d1kp8n3
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.56 — GroEL-intermediate domain like
超家族 Superfamily superfamily	d.56.1 — GroEL-intermediate domain like
家族 Family family	d.56.1.1 — GroEL-like chaperone, intermediate domain

CATH v4.4 (42 domains)

结构域编号 domain_id	1kp8A01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8A02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8A03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8B01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8B02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8B03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8C01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8C02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8C03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8D01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8D02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8D03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8E01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8E02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8E03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8F01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8F02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8F03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8G01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8G02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8G03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8H01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8H02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8H03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8I01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8I02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8I03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8J01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8J02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8J03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8K01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8K02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8K03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8L01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8L02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8L03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8M01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8M02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8M03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

结构域编号 domain_id	1kp8N01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	560 — GROEL; domain 1
同源超家族 H-superfamily homologous superfamily	10 — GroEL-like equatorial domain

结构域编号 domain_id	1kp8N02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	260 — GROEL; domain 2
同源超家族 H-superfamily homologous superfamily	10 — TCP-1-like chaperonin intermediate domain

结构域编号 domain_id	1kp8N03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	50 — 3-Layer(bba) Sandwich
拓扑 Topology topology	7 — GroEL
同源超家族 H-superfamily homologous superfamily	10 — GroEL

▶

晶胞边长 a length_a	135.571 Å
晶胞边长 b length_b	260.112 Å
晶胞边长 c length_c	150.200 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	101.14 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	28

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	2.000 Å
最低分辨率 resolution_low	39.890 Å
R 因子 r_factor	—
R_work r_work	0.2430
R_free r_free	0.2580

Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution

1. 蛋白身份与相关结构 Protein Identity & Related Structures

groEL protein

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1kp8__assembly_1__model_1

1kp8__assembly_1__model_1 | I(q)

1kp8__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 non-polymer

实体 6 Entity 6 water

6. 折叠分类 (SCOP + CATH) 84 domains

SCOP 2.08 (42 domains)

CATH v4.4 (42 domains)

7. 引用文献 (5)

Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution

1. 蛋白身份与相关结构 Protein Identity & Related Structures

groEL protein

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1kp8__assembly_1__model_1

1kp8__assembly_1__model_1 | I(q)

1kp8__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (6)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 non-polymer

实体 5 Entity 5 non-polymer

实体 6 Entity 6 water

6. 折叠分类 (SCOP + CATH) 84 domains

SCOP 2.08 (42 domains)

CATH v4.4 (42 domains)

7. 引用文献 (5)