Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
关键词 keywords
;protein-DNA complex; UP1; human telomeric repeat; hTR; TR2-11F; RRM; RNA Recognition Motif; 6-MI; 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine; hnRNP A1, DNA BINDING PROTEIN-DNA COMPLEX
;; DNA BINDING PROTEIN/DNA
实验方法 method
X-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles
;Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
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